Cancer Immunology Recent Publications

Phenotypic and genotypic evaluation of bleeding diagnostic dilemmas: Two case studies.Gu SX, Butt A, Schulz VP, Rinder HM, Lee AI, Gallagher PG, Hwa J, Bona RD. Blood Cells Mol Dis. 2025 Feb; 2024 Sep 10. PMID: 39260211.
Tertiary Lymphoid Structures and Immunotherapy: Challenges and Opportunities.Ruddle NH. Methods Mol Biol. 2025. PMID: 39527229.
Mouse Models Enable the Functional Investigation of Tertiary Lymphoid Structures in Cancer.Jeevanandam A, Yin Z, Connolly KA, Joshi NS. Methods Mol Biol. 2025. PMID: 39527217.
Vγ6/Vδ1 + γδ T cells protect from angiotensin II effects on blood pressure and endothelial function in mice.Mahmoud AUM, Caillon A, Shokoples B, Ferreira NS, Comeau K, Hatano S, Yoshikai Y, Lewis JM, Tigelaar RE, Paradis P, Schiffrin EL. J Hypertens. 2025 Jan 1; 2024 Sep 7. PMID: 39248136.
Efficacy and Safety of Denileukin Diftitox-Cxdl, an Improved Purity Formulation of Denileukin Diftitox, in Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma.Foss FM, Kim YH, Prince HM, Akilov OE, Querfeld C, Seminario-Vidal L, Fisher DC, Kuzel TM, Yannakou CK, Geskin LJ, Feldman T, Sokol L, Allen PB, Dang NH, Cabanillas F, Wong HK, Ooi CE, Xing D, Sauter N, Singh P, Czuczman M, Duvic M. J Clin Oncol. 2024 Dec 19; 2024 Dec 19. PMID: 39700456.
The art of dermatopathology.Ko CJ, McNiff JM. Clin Dermatol. 2024 Dec 17; 2024 Dec 17. PMID: 39701436.
Inducible cell lines producing replication-defective human immunodeficiency virus particles containing envelope glycoproteins stabilized in a pretriggered conformation.Ding H, Nguyen HT, Li W, Deshpande A, Zhang S, Jiang F, Zhang Z, Anang S, Mothes W, Sodroski J, Kappes JC. J Virol. 2024 Dec 17; 2024 Nov 7. PMID: 39508605.
A Yale Dermatology Perspective on Cutaneous T-Cell Lymphoma: Historical Reflection to Emerging Therapies.Swallow MA, Edelson R, Girardi M. Clin Dermatol. 2024 Dec 16; 2024 Dec 16. PMID: 39694197.
Medical Education in Dermatology.Imaeda S, Tomayko MM. Clin Dermatol. 2024 Dec 14; 2024 Dec 14. PMID: 39681292.
Vascular Endothelial Cells Derived from Transgene-Free Pig Induced Pluripotent Stem Cells for Vascular Tissue Engineering.Batty L, Park J, Qin L, Riaz M, Lin Y, Xu Z, Gao X, Li X, Lopez C, Zhang W, Hoareau M, Fallon ME, Huang Y, Luo H, Luo J, Ménoret S, Li P, Jiang Z, Smith P, Sachs DH, Tellides G, Ignacio Anegon, Pober JS, Liu P, Qyang Y. Acta Biomater. 2024 Dec 14; 2024 Dec 14. PMID: 39681154.
Author Correction: Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.Marsh SE, Walker AJ, Kamath T, Dissing-Olesen L, Hammond TR, de Soysa TY, Young AMH, Murphy S, Abdulraouf A, Nadaf N, Dufort C, Walker AC, Lucca LE, Kozareva V, Vanderburg C, Hong S, Bulstrode H, Hutchinson PJ, Gaffney DJ, Hafler DA, Franklin RJM, Macosko EZ, Stevens B. Nat Neurosci. 2024 Dec 13; 2024 Dec 13. PMID: 39672966.
Demographic diversity in platelet function and response to antiplatelet therapy.Jain K, Tyagi T, Gu SX, Faustino EVS, Hwa J. Trends Pharmacol Sci. 2024 Dec 12; 2024 Dec 12. PMID: 39672782.
Platelet-Monocyte Aggregate Instigates Inflammation and Vasculopathy in Kawasaki Disease.Zhang Y, Jia C, Guo M, Chen Q, Wen Y, Wang T, Xie Y, Fan X, Gao J, Yarovinsky TO, Liu R, Jiang Z, Wang M, Zhou J, Che D, Fu L, Edelson R, Gu X, Hwa J, Tang WH. Adv Sci (Weinh). 2024 Dec 12; 2024 Dec 12. PMID: 39665236.
Eating Disorders, Co-Morbid Disorders and Early Risk Factors Amongst Post-9/11 Veteran Men and Women.Cooper Z, Smith BN, Kehle-Forbes S, Dorset J, Mitchell KS. J Clin Psychol. 2024 Dec 8; 2024 Dec 8. PMID: 39648640.
Fully biologic endothelialized-tissue-engineered vascular conduits provide antithrombotic function and graft patency.Park J, Riaz M, Qin L, Zhang W, Batty L, Fooladi S, Kural MH, Li X, Luo H, Xu Z, Wang J, Banno K, Gu SX, Yuan Y, Anderson CW, Ellis MW, Zhou J, Luo J, Shi X, Shin JH, Liu Y, Lee S, Yoder MC, Elder RW, Mak M, Thorn S, Sinusas A, Gruber PJ, Hwa J, Tellides G, Niklason LE, Qyang Y. Cell Stem Cell. 2024 Dec 3; 2024 Dec 3. PMID: 39644899.
Mapping the gene space at single-cell resolution with gene signal pattern analysis.Venkat A, Leone S, Youlten SE, Fagerberg E, Attanasio J, Joshi NS, Perlmutter M, Krishnaswamy S. Nat Comput Sci. 2024 Dec; 2024 Dec 20. PMID: 39706866.
Postacute Sequelae of COVID-19 in Pediatric Patients Within the United States: A Scoping Review.Miller CM, Borre C, Green A, Funaro M, Oliveira CR, Iwasaki A. Am J Med Open. 2024 Dec; 2024 Sep 26. PMID: 39639960.
SARS-CoV-2 reprograms murine alveolar macrophages to dampen flu.Tabachnikova A, Iwasaki A. Trends Immunol. 2024 Dec; 2024 Nov 22. PMID: 39580310.
Lactate fermentation intoxicates TILs.Hunt BG, Kessler E, Joshi NS. Nat Immunol. 2024 Dec. PMID: 39516647.
The SV40 virus enhancer functions as a somatic hypermutation-targeting element with potential tumorigenic activity.Šenigl F, Soikkeli AI, Prost S, Schatz DG, Slavková M, Hejnar J, Alinikula J. Tumour Virus Res. 2024 Dec; 2024 Oct 28. PMID: 39490533.
Valemetostat monotherapy in patients with relapsed or refractory non-Hodgkin lymphoma: a first-in-human, multicentre, open-label, single-arm, phase 1 study.Maruyama D, Jacobsen E, Porcu P, Allen P, Ishitsuka K, Kusumoto S, Narita T, Tobinai K, Foss F, Tsukasaki K, Feldman T, Imaizumi Y, Izutsu K, Morishima S, Yamauchi N, Yuda J, Brammer JE, Kawamata T, Ruan J, Nosaka K, Utsunomiya A, Wang J, Zain J, Kakurai Y, Yamauchi H, Hizukuri Y, Biserna N, Tachibana M, Inoue A, Horwitz SM. Lancet Oncol. 2024 Dec; 2024 Oct 29. PMID: 39486432.
Cholesterol promotes IFNG mRNA expression in CD4(+) effector/memory cells by SGK1 activation.Hanin A, Comi M, Sumida TS, Hafler DA. Life Sci Alliance. 2024 Dec; 2024 Oct 4. PMID: 39366761.
National Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer.Kim LS, Moore MS, Schneider E, Canner J, Ayyala H, Chen J, Anant P, Graetz E, Lynch MA, Zanieski G, Gillego A, Valero MG, Proussaloglou EM, Berger ER, Golshan M, Greenup RA, Park TS. Ann Surg Oncol. 2024 Dec; 2024 Sep 25. PMID: 39322830.
Contemporary Approach to the Diagnosis and Classification of Myelodysplastic Neoplasms/Syndromes-Recommendations From the International Consortium for Myelodysplastic Neoplasms/Syndromes (MDS [icMDS]).Aakash F, Gisriel SD, Zeidan AM, Bennett JM, Bejar R, Bewersdorf JP, Borate UM, Boultwood J, Brunner AM, Buckstein R, Carraway HE, Churpek JE, Daver NG, DeZern AE, Efficace F, Fenaux P, Figueroa ME, Garcia-Manero G, Gore SD, Greenberg PL, Griffiths EA, Halene S, Hourigan CS, Kim TK, Kim N, Komrokji RS, Kutchroo VK, List AF, Little RF, Majeti R, Nazha A, Nimer SD, Odenike O, Padron E, Patnaik MM, Platzbecker U, Della Porta MG, Roboz GJ, Sallman DA, Santini V, Sanz G, Savona MR, Sekeres MA, Stahl M, Starczynowski DT, Steensma DP, Taylor J, Abdel-Wahab O, Wei AH, Xie Z, Xu ML, Hasserjian RP, Loghavi S. Mod Pathol. 2024 Dec; 2024 Sep 23. PMID: 39322118.
Incidence of Pathologic Nodal Disease in Clinically Node-Negative, Microinvasive or T1a Breast Cancers.Dey P, Kc M, Proussaloglou EM, Khubchandani JA, Kim L, Zanieski G, Park T, Lynch M, Gillego A, Valero M, Schneider E, Golshan M, Greenup RA, Berger ER. Ann Surg Oncol. 2024 Dec; 2024 Sep 6. PMID: 39240394.
Early thrombus formation is required for eccentric and heterogeneous neointimal hyperplasia under disturbed flow.Bai H, Li Z, Zhang W, Thaxton C, Ohashi Y, Gonzalez L, Kano M, Yatsula B, Hwa J, Dardik A. J Thromb Haemost. 2024 Dec; 2024 Aug 21. PMID: 39173878.
High-Dimensional Single-Cell Mass Cytometry Demonstrates Differential Platelet Functional Phenotypes in Infants With Congenital Heart Disease.Gu SX, Marcus BS, Gu VW, Varghese AP, Hwa J, Faustino EVS. Arterioscler Thromb Vasc Biol. 2024 Dec; 2024 Aug 22. PMID: 39171400.
The single-cell opioid responses in the context of HIV (SCORCH) consortium.Ament SA, Campbell RR, Lobo MK, Receveur JP, Agrawal K, Borjabad A, Byrareddy SN, Chang L, Clarke D, Emani P, Gabuzda D, Gaulton KJ, Giglio M, Giorgi FM, Gok B, Guda C, Hadas E, Herb BR, Hu W, Huttner A, Ishmam MR, Jacobs MM, Kelschenbach J, Kim DW, Lee C, Liu S, Liu X, Madras BK, Mahurkar AA, Mash DC, Mukamel EA, Niu M, O'Connor RM, Pagan CM, Pang APS, Pillai P, Repunte-Canonigo V, Ruzicka WB, Stanley J, Tickle T, Tsai SA, Wang A, Wills L, Wilson AM, Wright SN, Xu S, Yang J, Zand M, Zhang L, Zhang J, Akbarian S, Buch S, Cheng CS, Corley MJ, Fox HS, Gerstein M, Gummuluru S, Heiman M, Ho YC, Kellis M, Kenny PJ, Kluger Y, Milner TA, Moore DJ, Morgello S, Ndhlovu LC, Rana TM, Sanna PP, Satterlee JS, Sestan N, Spector SA, Spudich S, Tilgner HU, Volsky DJ, White OR, Williams DW, Zeng H. Mol Psychiatry. 2024 Dec; 2024 Jun 15. PMID: 38879719.
Chart review study of real-world clinical outcomes in patients with cutaneous T-cell lymphoma treated with extracorporeal photopheresis in the US in 2017-2019.Girardi M, Carlson K, Huang X, Corman SL, Edmundson P, Schmier J, Kale HP, Raina R, Foss F. J Dermatolog Treat. 2024 Dec; 2024 Jun 9. PMID: 38852942.
Sex-based differences in CEACAM5 expression in lung cancer.Woodard GA, Kane ER, Todorovic N, Prince S, Dacic S, Chen L. Transl Cancer Res. 2024 Nov 30; 2024 Nov 27. PMID: 39697744.
Safety and activity of CTX130, a CD70-targeted allogeneic CRISPR-Cas9-engineered CAR T-cell therapy, in patients with relapsed or refractory T-cell malignancies (COBALT-LYM): a single-arm, open-label, phase 1, dose-escalation study.Iyer SP, Sica RA, Ho PJ, Prica A, Zain J, Foss FM, Hu B, Beitinjaneh A, Weng WK, Kim YH, Khodadoust MS, Huen AO, Williams LM, Ma A, Huang E, Ganpule A, Nagar SD, Sripakdeevong P, Cullingford EL, Karnik S, Dequeant ML, Patel JN, He XS, Li Z, He QA, Mendonez JH, Keegan A, Horwitz SM. Lancet Oncol. 2024 Nov 28; 2024 Nov 28. PMID: 39617017.
VEXAS Syndrome: Histiocytoid Cells With Feathery Cytoplasm as a Clue to the Diagnosis.Ko CJ, Odell I, Gehlhausen JR, Leventhal J, McNiff JM, Zubek A. J Cutan Pathol. 2024 Nov 28; 2024 Nov 28. PMID: 39610062.
Circulating tumor-reactive KIR(+)CD8(+) T cells suppress anti-tumor immunity in patients with melanoma.Lu BY, Lucca LE, Lewis W, Wang J, Nogueira CV, Heer S, Rayon-Estrada V, Axisa PP, Reeves SM, Buitrago-Pocasangre NC, Pham GH, Kojima ML, Wei W, Aizenbud L, Bacchiocchi A, Zhang L, Walewski JJ, Chiang V, Olino K, Clune J, Halaban R, Kluger Y, Coyle AJ, Kisielow J, Obermair FJ, Kluger HM, Hafler DA. Nat Immunol. 2024 Nov 28; 2024 Nov 28. PMID: 39609626.
Setdb1-loss induces type-I interferons and immune clearance of melanoma.McGeary MK, Damsky W, Daniels AJ, Lang SM, Xu Q, Song E, Huet-Calderwood C, Lou HJ, Paradkar S, Micevic G, Kaech SM, Calderwood DA, Turk BE, Yan Q, Iwasaki A, Bosenberg MW. Cancer Immunol Res. 2024 Nov 26; 2024 Nov 26. PMID: 39589394.
Clonal hematopoiesis of indeterminate potential is associated with increased risk of immune checkpoint inhibitor myocarditis in a prospective study of a cardio-oncology cohort.Jaber Chehayeb R, Singh J, Matute-Martinez C, Chen NW, Guajardo AF, Lin D, Jayakrishnan R, Christofides A, Leveille E, Im Y, Biancon G, VanOudenhove J, Ibrahim E, Ardasheva A, Jha A, Hwa J, Halene S, Kwan JM. Cardiooncology. 2024 Nov 26; 2024 Nov 26. PMID: 39587635.
Differentiating Separate Primary Lung Adenocarcinomas From Intrapulmonary Metastases With Emphasis on Pathological and Molecular Considerations: Recommendations From the International Association for the Study of Lung Cancer Pathology Committee.Chou TY, Dacic S, Wistuba I, Beasley MB, Berezowska S, Chang YC, Chung JH, Connolly C, Han Y, Hirsch FR, Hwang DM, Janowczyk A, Joubert P, Kerr KM, Lin D, Minami Y, Mino-Kenudson M, Nicholson AG, Papotti M, Rekhtman N, Roden AC, von der Thüsen JH, Travis W, Tsao MS, Yatabe Y, Yeh YC, Bubendorf L, Chang WC, Denninghoff V, Fernandes Tavora FR, Hayashi T, Hofman P, Jain D, Kim TJ, Lantuejoul S, Le Quesne J, Lopez-Rios F, Matsubara D, Noguchi M, Radonic T, Saqi A, Schalper K, Shim HS, Sholl L, Weissferdt A, Cooper WA. J Thorac Oncol. 2024 Nov 22; 2024 Nov 22. PMID: 39579981.
CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells.Pellegrino B, David K, Rabani S, Lampert B, Tran T, Doherty E, Piecychna M, Meza-Romero R, Leng L, Hershkovitz D, Vandenbark AA, Bucala R, Becker-Herman S, Shachar I. PLoS Biol. 2024 Nov; 2024 Nov 22. PMID: 39576827.
Recurrent hyper-motif circuits in developmental programs.Adler M, Medzhitov R. bioRxiv. 2024 Nov 20; 2024 Nov 20. PMID: 39605580.
Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma.Schoenfeld DA, Djureinovic D, Su DG, Zhang L, Lu BY, Kamga L, Mann JE, Huck JD, Hurwitz M, Braun DA, Jilaveanu L, Ring AM, Kluger HM. JCI Insight. 2024 Nov 19; 2024 Nov 19. PMID: 39561007.
Electron tomography visualization of HIV-1 virions trapped by fusion inhibitors to host cells in infected tissues.Ladinsky MS, Zhu L, Ullah I, Uchil PD, Kumar P, Kay MS, Bjorkman PJ. J Virol. 2024 Nov 19; 2024 Oct 30. PMID: 39475277.
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19.Maguire C, Chen J, Rouphael N, Pickering H, Phan HV, Glascock A, Chu V, Dandekar R, Corry D, Kheradmand F, Baden LR, Selaky R, McComsey GA, Haddad EK, Cairns CB, Pulendran B, Fernandez-Sesma A, Simon V, Metcalf JP, Higuita NIA, Messer WB, David MM, Nadeau KC, Kraft M, Bime C, Schaenman J, Erle D, Calfee CS, Atkinson MA, Brackenridge SC, Ehrlich LIR, Montgomery RR, Shaw AC, Hough CL, Geng LN, Hafler DA, Augustine AD, Becker PM, Peters B, Ozonoff A, Kim-Schulze SH, Krammer F, Bosinger S, Eckalbar W, Altman MC, Wilson M, Guan L, Kleinstein SH, Smolen KK, Reed EF, Levy O, Maecker H, Hunt P, Steen H, Diray-Arce J, Langelier CR, Melamed E. bioRxiv. 2024 Nov 16; 2024 Nov 16. PMID: 39605478.
Sorafenib or anthracycline-based chemotherapy for progressive desmoid tumors.Costa PA, Arora A, Fernandez Y, Yi I, Bakkila B, Tan H, Barreto Coelho P, Campoverde L, Hardy N, Bialick S, Espejo Freire A, D'Amato GZ, Chang YC, Mesenger JP, Subhawong T, Haims A, Hurwitz M, Olino K, Turaga K, Deshpande H, Trent J. Cancer. 2024 Nov 14; 2024 Nov 14. PMID: 39543805.
Sex differences in postacute infection syndromes.Silva J, Iwasaki A. Sci Transl Med. 2024 Nov 13; 2024 Nov 13. PMID: 39536120.
Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties.Shin JH, Park J, Lim J, Jeong J, Dinesh RK, Maher SE, Kim J, Park S, Hong JY, Wysolmerski J, Choi J, Bothwell ALM. Elife. 2024 Nov 13; 2024 Nov 13. PMID: 39535280.
CD4 downregulation precedes Env expression and protects HIV-1-infected cells from ADCC mediated by non-neutralizing antibodies.Richard J, Sannier G, Zhu L, Prévost J, Marchitto L, Benlarbi M, Beaudoin-Bussières G, Kim H, Sun Y, Chatterjee D, Medjahed H, Bourassa C, Delgado G-G, Dubé M, Kirchhoff F, Hahn BH, Kumar P, Kaufmann DE, Finzi A. mBio. 2024 Nov 13; 2024 Oct 7. PMID: 39373535.
Deep Multimodal Representations and Classification of First-Episode Psychosis via Live Face Processing.Singh R, Zhang Y, Bhaskar D, Srihari V, Tek C, Zhang X, Adam Noah J, Krishnaswamy S, Hirsch J. bioRxiv. 2024 Nov 8; 2024 Nov 8. PMID: 39574662.
A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses.Yang Y, Treger RS, Hernandez-Bird J, Lu P, Mao T, Iwasaki A. Sci Immunol. 2024 Nov 8; 2024 Nov 8. PMID: 39514636.
The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation.Stacey JCV, Hrebík D, Nand E, Shetty SD, Qu K, Boicu M, Anders-Össwein M, Dick RA, Mothes W, Kräusslich HG, Müller B, Briggs JAG. bioRxiv. 2024 Nov 6; 2024 Nov 6. PMID: 39574591.
Pooled Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone in Patients With Advanced Melanoma.Long GV, Larkin J, Schadendorf D, Grob JJ, Lao CD, Márquez-Rodas I, Wagstaff J, Lebbé C, Pigozzo J, Robert C, Ascierto PA, Atkinson V, Postow MA, Atkins MB, Sznol M, Callahan MK, Topalian SL, Sosman JA, Kotapati S, Thakkar PK, Ritchings C, Pe Benito M, Re S, Soleymani S, Hodi FS. J Clin Oncol. 2024 Nov 6; 2024 Nov 6. PMID: 39504507.
Achieving Adherence With NCCN Guidelines for Nonmelanoma Skin Cancer Regarding Peripheral and Deep En Face Margin Assessment (PDEMA).Xu YG, Lim Y, Bordeaux JS, Aasi SZ, Alam M, Chen PL, Contreras CM, DiMaio D, Donigan JM, Farma JM, Grekin RC, Mark L, Nehal KS, Nghiem P, Olino K, Patel T, Scott J, Shaha AR, Srivastava D, Schmults CD. J Natl Compr Canc Netw. 2024 Nov. PMID: 39536442.
Data-driven, harmonised classification system for myelodysplastic syndromes: a consensus paper from the International Consortium for Myelodysplastic Syndromes.Komrokji RS, Lanino L, Ball S, Bewersdorf JP, Marchetti M, Maggioni G, Travaglino E, Al Ali NH, Fenaux P, Platzbecker U, Santini V, Diez-Campelo M, Singh A, Jain AG, Aguirre LE, Tinsley-Vance SM, Schwabkey ZI, Chan O, Xie Z, Brunner AM, Kuykendall AT, Bennett JM, Buckstein R, Bejar R, Carraway HE, DeZern AE, Griffiths EA, Halene S, Hasserjian RP, Lancet J, List AF, Loghavi S, Odenike O, Padron E, Patnaik MM, Roboz GJ, Stahl M, Sekeres MA, Steensma DP, Savona MR, Taylor J, Xu ML, Sweet K, Sallman DA, Nimer SD, Hourigan CS, Wei AH, Sauta E, D'Amico S, Asti G, Castellani G, Delleani M, Campagna A, Borate UM, Sanz G, Efficace F, Gore SD, Kim TK, Daver N, Garcia-Manero G, Rozman M, Orfao A, Wang SA, Foucar MK, Germing U, Haferlach T, Scheinberg P, Miyazaki Y, Iastrebner M, Kulasekararaj A, Cluzeau T, Kordasti S, van de Loosdrecht AA, Ades L, Zeidan AM, Della Porta MG. Lancet Haematol. 2024 Nov; 2024 Oct 9. PMID: 39393368.
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors.Skoulidis F, Araujo HA, Do MT, Qian Y, Sun X, Cobo AG, Le JT, Montesion M, Palmer R, Jahchan N, Juan JM, Min C, Yu Y, Pan X, Arbour KC, Vokes N, Schmidt ST, Molkentine D, Owen DH, Memmott R, Patil PD, Marmarelis ME, Awad MM, Murray JC, Hellyer JA, Gainor JF, Dimou A, Bestvina CM, Shu CA, Riess JW, Blakely CM, Pecot CV, Mezquita L, Tabbó F, Scheffler M, Digumarthy S, Mooradian MJ, Sacher AG, Lau SCM, Saltos AN, Rotow J, Johnson RP, Liu C, Stewart T, Goldberg SB, Killam J, Walther Z, Schalper K, Davies KD, Woodcock MG, Anagnostou V, Marrone KA, Forde PM, Ricciuti B, Venkatraman D, Van Allen EM, Cummings AL, Goldman JW, Shaish H, Kier M, Katz S, Aggarwal C, Ni Y, Azok JT, Segal J, Ritterhouse L, Neal JW, Lacroix L, Elamin YY, Negrao MV, Le X, Lam VK, Lewis WE, Kemp HN, Carter B, Roth JA, Swisher S, Lee R, Zhou T, Poteete A, Kong Y, Takehara T, Paula AG, Parra Cuentas ER, Behrens C, Wistuba II, Zhang J, Blumenschein GR, Gay C, Byers LA, Gibbons DL, Tsao A, Lee JJ, Bivona TG, Camidge DR, Gray JE, Lieghl N, Levy B, Brahmer JR, Garassino MC, Gandara DR, Garon EB, Rizvi NA, Scagliotti GV, Wolf J, Planchard D, Besse B, Herbst RS, Wakelee HA, Pennell NA, Shaw AT, Jänne PA, Carbone DP, Hellmann MD, Rudin CM, Albacker L, Mann H, Zhu Z, Lai Z, Stewart R, Peters S, Johnson ML, Wong KK, Huang A, Winslow MM, Rosen MJ, Winters IP, Papadimitrakopoulou VA, Cascone T, Jewsbury P, Heymach JV. Nature. 2024 Nov; 2024 Oct 9. PMID: 39385035.
IL-1β Induces Human Endothelial Surface Expression of IL-15 by Relieving let-7c-3p Suppression of Protein Translation.Mullan CW, Summer L, Lopez-Giraldez F, Tobiasova Z, Manes TD, Yasothan S, Song G, Jane-Wit D, Saltzman WM, Pober JS. J Immunol. 2024 Nov 1. PMID: 39302113.
ASTCT and USCLC Clinical Practice Recommendations for Allogeneic Stem Cell Transplant in Mycosis Fungoides and Sézary Syndrome.Goyal A, O'Leary D, Dabaja B, Weng WK, Zain J, Cutler C, Guitart J, Kim YH, Geskin LJ, Hoppe RT, Wilson LD, Beaven AW, Horwitz S, Allen PB, Barta SK, Bohjanen K, Brammer JE, Carter JB, Comfere N, DeSimone JA, Dusenbery K, Duvic M, Huen A, Jagadeesh D, Kelsey CR, Khodadoust MS, Lechowicz MJ, Mehta-Shah N, Moskowitz AJ, Olsen EA, Poh C, Pro B, Querfeld C, Sauter C, Sokol L, Sokumbi O, Wilcox RA, Zic JA, Hamadani M, Foss F. Transplant Cell Ther. 2024 Nov; 2024 Sep 1. PMID: 39222792.
Causes of death and patterns of metastatic disease at the end of life for patients with advanced melanoma in the immunotherapy era.Lee DY, McNamara M, Yang A, Yaskolko M, Kluger H, Tran T, Olino K, Clune J, Sznol M, Ishizuka JJ. Pigment Cell Melanoma Res. 2024 Nov; 2024 Jul 28. PMID: 39073002.
Global outcomes and prognosis for relapsed/refractory mature T-cell and NK-cell lymphomas: Results from PETAL consortium.Han JX, Koh MJ, Boussi L, Sorial M, McCabe SM, Peng L, Singh S, Eche-Ugwu IJ, Gabler J, Fernandez Turizo MJ, MacVicar CT, Garg AR, Disciullo A, Chopra K, Lenart AW, Nwodo E, Barnes JA, Koh MJ, Miranda ECM, Chiattone CS, Stuver RN, Horwitz SM, Merrill MH, Jacobsen ED, Manni M, Civallero M, Skrypets T, Lymboussaki A, Federico M, Kim YR, Kim JS, Cho JY, Eipe T, Shet T Dr, Epari S, Shetty A, Saha S, Jain H Dr, Sengar M MD, DM, Van Der Weyden C, Prince HM, Hamouche R, Muradashvili T, Foss FM, Gentilini M, Casadei B, Zinzani PL, Okatani T, Yoshida N, Yoon SE, Kim WS, Panchoo G, Mohamed Z, Verburgh E, Alturas JC, Al-Mansour M, Ford J, Cabrera ME, Ku A, Bhagat G, Ma H, Sawas A, Kariya KM, Iwasaki M, Bhanushali F, O'Connor OA, Marchi E, Shen C, Shah D, Jain S. Blood Adv. 2024 Oct 31; 2024 Oct 31. PMID: 39481087.
Single-cell transcriptomic and proteomic analysis of Parkinson's disease brains.Zhu B, Park JM, Coffey SR, Russo A, Hsu IU, Wang J, Su C, Chang R, Lam TT, Gopal PP, Ginsberg SD, Zhao H, Hafler DA, Chandra SS, Zhang L. Sci Transl Med. 2024 Oct 30; 2024 Oct 30. PMID: 39475571.
NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks.Koonce NL, Emerson SE, Bhaskar D, Kuchroo M, Moyle MW, Arroyo-Morales P, Martínez NV, Krishnaswamy S, Mohler W, Colón-Ramos D. bioRxiv. 2024 Oct 24; 2024 Oct 24. PMID: 39484462.
The KT Jeang retrovirology prize 2024: Walther Mothes.Mothes W. Retrovirology. 2024 Oct 24; 2024 Oct 24. PMID: 39449025.
Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.Ihedioha OC, Marcarian HQ, Sivakoses A, Beverley SM, McMahon-Pratt D, Bothwell ALM. Front Immunol. 2024; 2024 Oct 22. PMID: 39502693.
ASO Author Reflections: Home Recovery After Mastectomy: Embracing a New Era of Postmastectomy Care.Kim LS, Park TS. Ann Surg Oncol. 2024 Oct 18; 2024 Oct 18. PMID: 39422846.
Mucosal sugars delineate pyrazine vs pyrazinone autoinducer signaling in Klebsiella oxytoca.Hamchand R, Wang K, Song D, Palm NW, Crawford JM. Nat Commun. 2024 Oct 16; 2024 Oct 16. PMID: 39406708.
Characterization and implementation of the MarathonRT template-switching reaction to expand the capabilities of RNA-seq.Guo LT, Grinko A, Olson S, Leipold AM, Graveley B, Saliba AE, Pyle AM. RNA. 2024 Oct 16; 2024 Oct 16. PMID: 39174298.
New potential ligand-receptor axis involved in tissue repair as therapeutic targets in progressive multiple sclerosis.Carrera Silva EA, Correale J, Rothlin C, Ortiz Wilczyñski JM. J Pharmacol Exp Ther. 2024 Oct 8; 2024 Oct 8. PMID: 39379148.
Sensing DNA as danger: The discovery of cGAS.Flavell RA, Sefik E. Immunity. 2024 Oct 8; 2024 Sep 19. PMID: 39303723.
Evaluation of Benzene Presence and Formation in Benzoyl Peroxide Drug Products.Kucera K, Zenzola N, Hudspeth A, Dubnicka M, Hinz W, Bunick CG, Girardi M, Dabestani A, Light DY. J Invest Dermatol. 2024 Oct 7; 2024 Oct 7. PMID: 39384016.
Feeding the wrath with myelin.Ghosh S, Rothlin CV. Trends Immunol. 2024 Oct; 2024 Sep 27. PMID: 39341708.
Immune Cell Dynamics in EGFR-Mutated NSCLC Treated With Afatinib and Pembrolizumab: Results From a Phase IB Study.Riess JW, Lara MS, Lopez de Rodas M, Luxardi G, Herbert S, Shimoda M, Kelly K, Meerlev A, Moore E, Beckett L, Monjazeb A, Schalper K, Maverakis E, Gandara DR. JTO Clin Res Rep. 2024 Oct; 2024 Jul 14. PMID: 39318388.
Addressing platelet insecurity - A national call to action.Gehrie EA, Young PP, Basavaraju SV, Bracey AW, Cap AP, Culler L, Dunbar NM, Homer M, Isufi I, Macedo R, Petraszko T, Ramsey G, Tormey CA, Kaufman RM, Snyder EL. Transfusion. 2024 Oct; 2024 Aug 12. PMID: 39133194.
Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway.Hung CT, Ma C, Panda SK, Trsan T, Hodel M, Frein J, Foster A, Sun S, Wu HT, Kern J, Mishra R, Jain U, Ho YC, Colonna M, Stappenbeck TS, Liu TC. Mucosal Immunol. 2024 Oct; 2024 Jul 9. PMID: 38992433.
Percent Final Height Is a Novel Method That Identifies Differences Between the Rate of Development in American Children of Different Races.Taylor TN, Yang AA, Lee TM, Diejomaoh RM, Bridges CS, Kan JH, Smith BG, Cooperman DR. J Pediatr Orthop. 2024 Oct 1; 2024 Jun 28. PMID: 38938106.
Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination.Wu L, Yadavalli AD, Matos-Rodrigues G, Xu D, Pintado-Urbanc AP, Simon MD, Wu W, Nussenzweig A, Schatz DG. bioRxiv. 2024 Sep 26; 2024 Sep 26. PMID: 39386505.
Interpersonal emotion regulation and depressive symptoms in parent-adolescent dyads: A daily-diary investigation.Gadassi-Polack R, Questel M, Sened H, Marshall HE, Chen GJ, Geiger EJ, Bar Yosef T, Joormann J. Emotion. 2024 Sep 26; 2024 Sep 26. PMID: 39325395.
Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties.Shin JH, Park J, Lim J, Jeong J, Dinesh RK, Maher SE, Kim J, Park S, Hong JY, Wysolmerski J, Choi J, Bothwell ALM. bioRxiv. 2024 Sep 25; 2024 Sep 25. PMID: 38659853.
Randomized Phase III SIERRA Trial of (131)I-Apamistamab Before Allogeneic Hematopoietic Cell Transplantation Versus Conventional Care for Relapsed/Refractory AML.Gyurkocza B, Nath R, Seropian S, Choe H, Litzow MR, Abboud C, Koshy N, Stiff P, Tomlinson B, Abhyankar S, Foran J, Hari P, Chen G, Al-Kadhimi Z, Kebriaei P, Sabloff M, Orozco JJ, Jamieson K, Silverman M, Van Besien K, Schuster M, Law AD, Larkin K, Pandit-Taskar N, Rowley SD, Munshi P, Cook R, Levy MY, Lazarus HM, Sandmaier BM, Pagel JM, Reddy V, MacDougall J, McNamara K, Spross J, Haeuber E, Vusirikala M, Nahar A, Desai A, Giralt S. J Clin Oncol. 2024 Sep 19; 2024 Sep 19. PMID: 39298738.
Hyperedge Representations with Hypergraph Wavelets: Applications to Spatial Transcriptomics.Sun X, Xu C, Rocha JF, Liu C, Hollander-Bodie B, Goldman L, DiStasio M, Perlmutter M, Krishnaswamy S. ArXiv. 2024 Sep 14; 2024 Sep 14. PMID: 39314512.
The myokine FGF21 associates with enhanced survival in ALS and mitigates stress-induced cytotoxicity.Guha A, Si Y, Smith R, Kazamel M, Jiang N, Smith KA, Thalacker-Mercer A, Singh BK, Ho R, Andrabi SA, Pereira JDTDS, Salgado JS, Agrawal M, Velic EH, King PH. bioRxiv. 2024 Sep 14; 2024 Sep 14. PMID: 39314333.
Phase 2 trial of the farnesyltransferase inhibitor tipifarnib for relapsed/refractory peripheral T-cell lymphoma.Witzig T, Sokol L, Kim WS, de la Cruz Vicente F, Martín García-Sancho A, Advani R, Roncero Vidal JM, de Oña Navarrete R, Marín-Niebla A, Rodriguez Izquierdo A, Terol MJ, Domingo-Domenech E, Saunders A, Bendris N, Mackey J, Leoni M, Foss F. Blood Adv. 2024 Sep 10. PMID: 38991123.
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Immunity. 2024 Sep 10; 2024 Jun 20. PMID: 38906145.
Real World Data on Efficacy and Safety of EPOCH in T-Cell Lymphoma.Straining R, Foss F, Schiffer M, Amin K, Agarwal S, Isufi I, Huntington S, Kothari S, Seropian S, Girardi M, Sethi T. Clin Lymphoma Myeloma Leuk. 2024 Sep 8; 2024 Sep 8. PMID: 39368885.
Putting computational models of immunity to the test - an invited challenge to predict B. pertussis vaccination outcomes.Shinde P, Willemsen L, Anderson M, Aoki M, Basu S, Burel JG, Cheng P, Dastidar SG, Dunleavy A, Einav T, Forschmiedt J, Fourati S, Garcia J, Gibson W, Greenbaum JA, Guan L, Guan W, Gygi JP, Ha B, Hou J, Hsiao J, Huang Y, Jansen R, Kakoty B, Kang Z, Kobie JJ, Kojima M, Konstorum A, Lee J, Lewis SA, Li A, Lock EF, Mahita J, Mendes M, Meng H, Neher A, Nili S, Olsen LR, Orfield S, Overton JA, Pai N, Parker C, Qian B, Rasmussen M, Reyna J, Richardson E, Safo S, Sorenson J, Srinivasan A, Thrupp N, Tippalagama R, Trevizani R, Ventz S, Wang J, Wu CC, Ay F, Grant B, Kleinstein SH, Peters B. bioRxiv. 2024 Sep 8; 2024 Sep 8. PMID: 39282381.
Clinical and Histologic Variants of CD8+ Cutaneous T-Cell Lymphomas.Swallow MA, Micevic G, Zhou A, Carlson KR, Foss FM, Girardi M. Cancers (Basel). 2024 Sep 5; 2024 Sep 5. PMID: 39272944.
Beta Spike-Presenting SARS-CoV-2 Virus-like Particle Vaccine Confers Broad Protection against Other VOCs in Mice.Ullah I, Symmes K, Keita K, Zhu L, Grunst MW, Li W, Mothes W, Kumar P, Uchil PD. Vaccines (Basel). 2024 Sep 2; 2024 Sep 2. PMID: 39340037.
Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis.Joshi D, Coon BG, Chakraborty R, Deng H, Yang Z, Babar MU, Fernandez-Tussy P, Meredith E, Attanasio J, Joshi N, Traylor JG Jr, Orr AW, Fernandez-Hernando C, Libreros S, Schwartz MA. Nat Cardiovasc Res. 2024 Sep; 2024 Sep 4. PMID: 39232138.
Understanding emerging and re-emerging viruses to facilitate pandemic preparedness.Zapatero-Belinchón FJ, Kumar P, Ott M, Schwartz O, Sigal A. Nat Microbiol. 2024 Sep. PMID: 39198691.
Stem cells tightly regulate dead cell clearance to maintain tissue fitness.Stewart KS, Abdusselamoglu MD, Tierney MT, Gola A, Hur YH, Gonzales KAU, Yuan S, Bonny AR, Yang Y, Infarinato NR, Cowley CJ, Levorse JM, Pasolli HA, Ghosh S, Rothlin CV, Fuchs E. Nature. 2024 Sep; 2024 Aug 21. PMID: 39169186.
Ultra-sensitive molecular residual disease detection through whole genome sequencing with single-read error correction.Li X, Liu T, Bacchiocchi A, Li M, Cheng W, Wittkop T, Mendez FL, Wang Y, Tang P, Yao Q, Bosenberg MW, Sznol M, Yan Q, Faham M, Weng L, Halaban R, Jin H, Hu Z. EMBO Mol Med. 2024 Sep; 2024 Aug 20. PMID: 39164471.
Quantitative Measurement of HER2 Expression in Non-Small Cell Lung Cancer With a High-Sensitivity Assay.Liu M, Vathiotis I, Robbins CJ, Chan NNN, Moutafi M, Burela S, Xirou V, Schalper KA, Herbst RS, Syrigos K, Rimm DL. Mod Pathol. 2024 Sep; 2024 Jul 2. PMID: 38964502.
A unified metric of human immune health.Sparks R, Rachmaninoff N, Lau WW, Hirsch DC, Bansal N, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat JD, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Nat Med. 2024 Sep; 2024 Jul 3. PMID: 38961223.
Factors Associated with Long COVID Recovery among US Adults.Shah KM, Shah RM, Sawano M, Wu Y, Bishop P, Iwasaki A, Krumholz HM. Am J Med. 2024 Sep; 2024 Apr 21. PMID: 38649004.
Prominent role of gut dysbiosis in the pathogenesis of cystic fibrosis-related liver disease in mice.Bertolini A, Nguyen M, Zehra SA, Taleb SA, Bauer-Pisani T, Palm N, Strazzabosco M, Fiorotto R. J Hepatol. 2024 Sep; 2024 Mar 28. PMID: 38554847.
BCAM (basal cell adhesion molecule) protein expression in different tumor populations.Burela S, He M, Trontzas IP, Gavrielatou N, Schalper KA, Langermann S, Flies DB, Rimm DL, Aung TN. Discov Oncol. 2024 Aug 29; 2024 Aug 29. PMID: 39207605.
An autoimmune transcriptional circuit drives FOXP3(+) regulatory T cell dysfunction.Sumida TS, Lincoln MR, He L, Park Y, Ota M, Oguchi A, Son R, Yi A, Stillwell HA, Leissa GA, Fujio K, Murakawa Y, Kulminski AM, Epstein CB, Bernstein BE, Kellis M, Hafler DA. Sci Transl Med. 2024 Aug 28; 2024 Aug 28. PMID: 39196959.
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC.Richard J, Grunst MW, Niu L, Díaz-Salinas MA, Tolbert WD, Marchitto L, Zhou F, Bourassa C, Yang D, Chiu TJ, Chen HC, Benlarbi M, Gottumukkala S, Li W, Dionne K, Bélanger É, Chatterjee D, Medjahed H, Hendrickson WA, Sodroski J, Lang ZC, Morton AJ, Huang RK, Matthies D, Smith AB 3rd, Mothes W, Munro JB, Pazgier M, Finzi A. bioRxiv. 2024 Aug 27; 2024 Aug 27. PMID: 39253431.
Design of soluble HIV-1 envelope trimers free of covalent gp120-gp41 bonds with prevalent native-like conformation.Zhang P, Gorman J, Tsybovsky Y, Lu M, Liu Q, Gopan V, Singh M, Lin Y, Miao H, Seo Y, Kwon A, Olia AS, Chuang GY, Geng H, Lai YT, Zhou T, Mascola JR, Mothes W, Kwong PD, Lusso P. Cell Rep. 2024 Aug 27; 2024 Jul 18. PMID: 39028623.
Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance.Yu J, Yan Y, Li S, Xu Y, Parolia A, Rizvi S, Wang W, Zhai Y, Xiao R, Li X, Liao P, Zhou J, Okla K, Lin H, Lin X, Grove S, Wei S, Vatan L, Hu J, Szumilo J, Kotarski J, Freeman ZT, Skala S, Wicha M, Cho KR, Chinnaiyan AM, Schon S, Wen F, Kryczek I, Wang S, Chen L, Zou W. Cell. 2024 Aug 22; 2024 Jul 4. PMID: 38968937.
Electron tomography visualization of HIV-1 virions trapped by fusion inhibitors to host cells in infected tissues.Ladinsky MS, Zhu L, Ullah I, Uchil PD, Kumar P, Kay MS, Bjorkman PJ. bioRxiv. 2024 Aug 19; 2024 Aug 19. PMID: 39229189.
Structure and inhibition of SARS-CoV-2 spike refolding in membranes.Grunst MW, Qin Z, Dodero-Rojas E, Ding S, Prévost J, Chen Y, Hu Y, Pazgier M, Wu S, Xie X, Finzi A, Onuchic JN, Whitford PC, Mothes W, Li W. Science. 2024 Aug 16; 2024 Aug 15. PMID: 39146425.
SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodeling.Xu Y, Zhang H, Chen Y, Pober JS, Zhou M, Zhou JH, Min W. Nat Commun. 2024 Aug 13; 2024 Aug 13. PMID: 39134547.
The amalgam of naive CD4(+) T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response.Even Z, Meli AP, Tyagi A, Vidyarthi A, Briggs N, de Kouchkovsky DA, Kong Y, Wang Y, Waizman DA, Rice TA, De Kumar B, Wang X, Palm NW, Craft J, Basu MK, Ghosh S, Rothlin CV. Immunity. 2024 Aug 13; 2024 Aug 2. PMID: 39096910.