2016
Clinical efficacy of 2-phase versus 4-phase computed tomography for localization in primary hyperparathyroidism
Ramirez A, Shada A, Martin A, Raghavan P, Durst C, Mukherjee S, Gaughen J, Ornan D, Hanks J, Smith P. Clinical efficacy of 2-phase versus 4-phase computed tomography for localization in primary hyperparathyroidism. Surgery 2016, 160: 731-737. PMID: 27302106, PMCID: PMC4975639, DOI: 10.1016/j.surg.2016.04.016.Peer-Reviewed Original ResearchConceptsPositive predictive valueFour-dimensional computed tomographyComputed tomography protocolComputed tomographyMultiglandular diseaseParathyroid localizationOperative findingsPredictive valueFour-phase computed tomographyLocalization of abnormal glandsRadiation doseTechnical surgical successEffective radiation doseFisher's exact testTomography protocolAbnormal glandsPrimary hyperparathyroidismSurgical successReoperative casesParathyroid weightSurgical outcomesTechnical successClinical efficacyOperative treatmentClinical outcomes
2015
Defining the effects of age and gender on immune response and outcomes to melanoma vaccination: a retrospective analysis of a single-institution clinical trials’ experience
Ramirez A, Wages N, Hu Y, Smolkin M, Slingluff C. Defining the effects of age and gender on immune response and outcomes to melanoma vaccination: a retrospective analysis of a single-institution clinical trials’ experience. Cancer Immunology, Immunotherapy 2015, 64: 1531-1539. PMID: 26392296, PMCID: PMC4644444, DOI: 10.1007/s00262-015-1758-5.Peer-Reviewed Original ResearchConceptsDisease-free survivalT cell responsesOverall survivalImmune responseOlder patientsCancer vaccinesClinical outcomesResected stage IIB-IV melanomaCD8+ T cell responsesStage IIB-IV melanomaLonger disease-free survivalImpact of patient ageMelanoma-associated peptidesCancer vaccine trialsClinical trial experienceIncidence of IRCumulative incidence rateKaplan-Meier estimatesClass I MHCMelanoma vaccineMenopausal statusPatient ageSurvival outcomesStratify patientsFemale patients