2022
Optimizing Small, Low-Risk, Unruptured Intracranial Aneurysm Treatment Using Game Theory
Boltyenkov A, Wang J, Malhotra A, Katz J, Dehdashti A, White T, Martinez G, Pandya A, Sanelli P. Optimizing Small, Low-Risk, Unruptured Intracranial Aneurysm Treatment Using Game Theory. American Journal Of Neuroradiology 2022, 43: 176-180. PMID: 35027349, PMCID: PMC8985687, DOI: 10.3174/ajnr.a7392.Peer-Reviewed Original Research
2019
Screening for Intracranial Aneurysms in Patients with Thoracic Aortic Aneurysms
Malhotra A, Seifert K, Wu X, Matouk C, Elefteriades JA. Screening for Intracranial Aneurysms in Patients with Thoracic Aortic Aneurysms. Cerebrovascular Diseases 2019, 47: 253-259. PMID: 31412341, DOI: 10.1159/000501194.Peer-Reviewed Original ResearchConceptsPrevalence of IAsThoracic aortic aneurysmIntracranial aneurysmsRetrospective studyAortic aneurysmRisk factorsPrevious retrospective studySignificant risk factorsPotential risk factorsMagnetic resonance angiogramStudent's t-testPatient demographicsUnivariate analysisHigh prevalenceLarge cohortGeneral populationPatientsAneurysmsPrevalenceCategorical variablesΧ2 testHypertensionT-testContinuous variablesIA locationCost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomesComparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm.
Malhotra A, Wu X, Miller T, Matouk CC, Sanelli P, Gandhi D. Comparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm. Journal Of Neurosurgery 2019, 132: 42-50. PMID: 30641830, DOI: 10.3171/2018.8.jns181080.Peer-Reviewed Original ResearchConceptsPipeline Embolization DeviceStent-assisted coilingRetreatment rateSmall unruptured aneurysmsComparative effectiveness analysisProbabilistic sensitivity analysesUnruptured aneurysmsEndovascular coilingHealth benefitsUse of PEDHigher health benefitsRate of recurrenceFavorable treatment strategyDecision-analytical studyStent-assisted techniquePED placementTreatment modalitiesEffectiveness analysisTreatment strategiesSmall aneurysmsEmbolization DeviceSimple coilingOutcome riskAneurysmsRetreatment
2017
Letter to the Editor Regarding “Growth of Untreated Unruptured Small-sized Aneurysms (<7 mm): Incidence and Related Factors”
Malhotra A, Wu X, Tu L, Seifert K. Letter to the Editor Regarding “Growth of Untreated Unruptured Small-sized Aneurysms (<7 mm): Incidence and Related Factors”. Clinical Neuroradiology 2017, 28: 307-308. PMID: 29052743, DOI: 10.1007/s00062-017-0638-0.Peer-Reviewed Original Research
2016
High-resolution Vessel Wall Magnetic Resonance Imaging in Intracranial Aneurysms and Brain Arteriovenous Malformations
Matouk CC, Cord BJ, Yeung J, Malhotra A, Johnson MH, Minja FJ. High-resolution Vessel Wall Magnetic Resonance Imaging in Intracranial Aneurysms and Brain Arteriovenous Malformations. Topics In Magnetic Resonance Imaging 2016, 25: 49-55. PMID: 27049241, DOI: 10.1097/rmr.0000000000000084.Peer-Reviewed Original ResearchConceptsHigh-resolution vessel wall magnetic resonance imagingVessel wall magnetic resonance imagingMagnetic resonance imagingArteriovenous malformationsResonance imagingIntracranial aneurysmsSteno-occlusive diseaseBrain arteriovenous malformationsCerebrovascular diseaseClinical evaluationAcademic centersClinical practiceVW-MRIConventional imagingAneurysmsMalformationsDiseaseRegarding “Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years”
Malhotra A, Wu X, Kalra V, Matouk C, Forman H. Regarding “Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years”. American Journal Of Neuroradiology 2016, 37: e39-e39. PMID: 26822726, PMCID: PMC7960187, DOI: 10.3174/ajnr.a4708.Commentaries, Editorials and Letters
2014
Use of Follow-Up Imaging in Isolated Perimesencephalic Subarachnoid Hemorrhage
Kalra VB, Wu X, Matouk CC, Malhotra A. Use of Follow-Up Imaging in Isolated Perimesencephalic Subarachnoid Hemorrhage. Stroke 2014, 46: 401-406. PMID: 25523050, DOI: 10.1161/strokeaha.114.007370.Peer-Reviewed Original ResearchConceptsPerimesencephalic subarachnoid hemorrhageInitial digital subtraction angiographyDigital subtraction angiographySubtraction angiographySubarachnoid hemorrhageNegative CTARetrospective institutional analysisFollow-up imagingInitial diagnosisTomographic angiogramInitial CTANoncontrast CTPatientsInstitutional reviewAneurysmsAngiographyImaging studiesExperienced neuroradiologistsIntracranial aneurysmsMultiple followMultiple studiesCTAHemorrhageCareful reviewAdditional use
2013
Vessel Wall Magnetic Resonance Imaging Identifies the Site of Rupture in Patients With Multiple Intracranial AneurysmsProof of Principle
Matouk CC, Mandell DM, Günel M, Bulsara KR, Malhotra A, Hebert R, Johnson MH, Mikulis DJ, Minja FJ. Vessel Wall Magnetic Resonance Imaging Identifies the Site of Rupture in Patients With Multiple Intracranial AneurysmsProof of Principle. Neurosurgery 2013, 72: 492-496. PMID: 23151622, DOI: 10.1227/neu.0b013e31827d1012.Peer-Reviewed Original ResearchConceptsAneurysmal subarachnoid hemorrhageSite of ruptureSubarachnoid hemorrhageMultiple intracranial aneurysmsMR-VWIHigh-resolution magnetic resonance vessel wall imagingIntracranial aneurysmsSteno-occlusive cerebrovascular diseaseVessel wall magnetic resonance imagingMR imaging findingsVessel wall enhancementMagnetic resonance vessel wall imagingMagnetic resonance imagingVessel wall imagingDefinitive treatmentCerebrovascular diseaseImaging findingsMedical recordsRuptured aneurysmsUnruptured aneurysmsPatientsAneurysmsWall enhancementResonance imagingRupture
2011
Loeys-Dietz syndrome: cardiovascular, neuroradiological and musculoskeletal imaging findings
Kalra VB, Gilbert JW, Malhotra A. Loeys-Dietz syndrome: cardiovascular, neuroradiological and musculoskeletal imaging findings. Pediatric Radiology 2011, 41: 1495-1504. PMID: 21785848, DOI: 10.1007/s00247-011-2195-z.Peer-Reviewed Original ResearchConceptsLoeys-Dietz syndromeAutosomal dominant connective tissue disorderProphylactic surgical interventionShort-interval followFollow-up imagingConnective tissue disordersEhlers-Danlos syndromeCardiovascular complicationsAggressive courseArterial dissectionRadiological manifestationsImaging findingsSurgical interventionVascular subtypeTissue disordersEarly diagnosisSimilar disordersSkeletal abnormalitiesComplicationsDisordersCraniofacial malformationsSyndromeImagingMorbidityAneurysms