2024
Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohort
2022
Brain injury patterns in hypoxic ischemic encephalopathy of term neonates
Bobba PS, Malhotra A, Sheth KN, Taylor SN, Ment LR, Payabvash S. Brain injury patterns in hypoxic ischemic encephalopathy of term neonates. Journal Of Neuroimaging 2022, 33: 79-84. PMID: 36164277, DOI: 10.1111/jon.13052.Peer-Reviewed Original ResearchConceptsSevere hypoxic-ischemic encephalopathyHypoxic-ischemic encephalopathyHypoxic-ischemic lesionsSeverity of HIEModerate hypoxic-ischemic encephalopathyTerm neonatesIschemic lesionsDiffusion-weighted imagingBasal gangliaDiagnosis of HIESeverity categoriesBrain injury patternsDeep white matterMRI diffusion-weighted imagingT2-weighted imagesPresence of lesionsVoxel-wise analysisRespiration (APGAR) scoreInfarct volumeStandard brain spaceIschemic encephalopathyInjury patternsBrain injuryLentiform nucleusLesion volume
2019
Differentiation of lymphomatous, metastatic, and non-malignant lymphadenopathy in the neck with quantitative diffusion-weighted imaging: systematic review and meta-analysis
Payabvash S, Brackett A, Forghani R, Malhotra A. Differentiation of lymphomatous, metastatic, and non-malignant lymphadenopathy in the neck with quantitative diffusion-weighted imaging: systematic review and meta-analysis. Neuroradiology 2019, 61: 897-910. PMID: 31175398, DOI: 10.1007/s00234-019-02236-7.Peer-Reviewed Original ResearchConceptsCervical lymph nodesAverage apparent diffusion coefficientStandardized mean differenceLymph nodesNon-malignant nodesDiagnostic odds ratioCervical lymphadenopathySubgroup analysisADC thresholdSystematic reviewSuspicious cervical lymph nodesUnknown primary cancer siteMean differenceNon-malignant lymphadenopathyCochrane Central RegisterNeck lymph nodesPrimary cancer siteConfidence intervalsSROC AUCRandom-effects modelComprehensive literature searchAverage ADC valueDiffusion-weighted imagingQuantitative diffusion-weighted imagingCentral RegisterQuantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis
Payabvash S, Chan A, Maralani P, Malhotra A. Quantitative diffusion magnetic resonance imaging for prediction of human papillomavirus status in head and neck squamous-cell carcinoma: A systematic review and meta-analysis. The Neuroradiology Journal 2019, 32: 232-240. PMID: 31084347, PMCID: PMC6639646, DOI: 10.1177/1971400919849808.Peer-Reviewed Original ResearchConceptsNeck squamous cell carcinomaDiffusion-weighted imagingHPV-positive HNSCCSquamous cell carcinomaHPV-negative HNSCCPrimary tumor lesionsStandardized mean differenceQuantitative diffusion magnetic resonancePrimary lesionHPV statusTumor lesionsAverage ADCDiffusion magnetic resonanceMean differenceHiggins' inconsistency indexHuman papillomavirus (HPV) statusHuman papillomavirus infectionApparent diffusion coefficient (ADC) valuesRandom-effects modelNoninvasive imaging biomarkerComprehensive literature searchAverage ADC valueEcho-planar diffusion-weighted imagingFixed-effects modelPapillomavirus infection