2019
Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomes
2018
Risk of Radiation-Induced Cancer From Computed Tomography Angiography Use in Imaging Surveillance for Unruptured Cerebral Aneurysms
Malhotra A, Wu X, Chugh A, Mustafa A, Matouk CC, Gandhi D, Sanelli P. Risk of Radiation-Induced Cancer From Computed Tomography Angiography Use in Imaging Surveillance for Unruptured Cerebral Aneurysms. Stroke 2018, 50: 76-82. PMID: 30580703, DOI: 10.1161/strokeaha.118.022454.Peer-Reviewed Original ResearchSurveillance imagingExcess lifetime riskCancer riskAneurysmal ruptureLifetime riskCancer incidenceRadiation Risk Assessment ToolIntracranial aneurysmsLonger surveillance periodsRadiation-induced cancer riskBrain cancer incidenceHigh-risk groupUnruptured cerebral aneurysmsCost-effectiveness/utility analysesBEIR VII reportRisk of radiationNoninvasive imaging modalityRisk assessment toolExcess cancer riskAngiography useImaging surveillanceTomography angiographySurveillance periodRisk groupsCerebral aneurysmsLetter to the Editor. Computed tomography angiography for the diagnosis of blunt cerebrovascular injury.
Malhotra A, Wu X, Tu L, Seifert K. Letter to the Editor. Computed tomography angiography for the diagnosis of blunt cerebrovascular injury. Journal Of Neurosurgery 2018, 129: 265-267. PMID: 29749913, DOI: 10.3171/2017.11.jns172884.Peer-Reviewed Original ResearchLetter to the Editor Regarding “Yield of Computed Tomography (CT) Angiography in Patients with Acute Headache, Normal Neurological Examination, and Normal Non Contrast CT: A Meta-Analysis”
Malhotra A, Wu X, Seifert K, Tu L. Letter to the Editor Regarding “Yield of Computed Tomography (CT) Angiography in Patients with Acute Headache, Normal Neurological Examination, and Normal Non Contrast CT: A Meta-Analysis”. Journal Of Stroke And Cerebrovascular Diseases 2018, 27: 2043. PMID: 29571755, DOI: 10.1016/j.jstrokecerebrovasdis.2018.02.049.Peer-Reviewed Original Research
2016
Should Patients Be Counseled About Possible Recurrence of Perimesencephalic Subarachnoid Hemorrhage?
Malhotra A, Wu X, Borse R, Matouk CC, Bulsara K. Should Patients Be Counseled About Possible Recurrence of Perimesencephalic Subarachnoid Hemorrhage? World Neurosurgery 2016, 94: 580.e17-580.e22. PMID: 27521726, DOI: 10.1016/j.wneu.2016.07.112.Peer-Reviewed Original ResearchConceptsPerimesencephalic subarachnoid hemorrhageAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageTomography angiographyBetter outcomesBenign natural courseNew neurologic signsComputed tomography angiographyHistory of traumaPossibility of recurrenceDigital subtraction angiographyRecurrent hemorrhageSevere headacheVascular anomaliesNeurologic signsCase reportNatural courseInitial episodeSixth decadeSubarachnoid bleedSudden onsetPossible recurrenceLower riskPatientsPrevious episodes
2015
Predictors of Vertebral Artery Injury in Isolated C2 Fractures Based on Fracture Morphology Using CT Angiography
Durand D, Wu X, Kalra VB, Abbed KM, Malhotra A. Predictors of Vertebral Artery Injury in Isolated C2 Fractures Based on Fracture Morphology Using CT Angiography. Spine 2015, 40: e713-e718. PMID: 25803220, DOI: 10.1097/brs.0000000000000893.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCervical VertebraeDatabases, FactualFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSpinal FracturesTomography, X-Ray ComputedTrauma CentersVascular System InjuriesVertebral ArteryYoung AdultConceptsVertebral artery injuryC2 fracturesComputed tomography angiographyTransverse foramenTomography angiographyArtery injuryLevel I trauma centerInstitutional board review approvalTransverse foramen fracturesType III densI trauma centerVertebral body fracturesRetrospective database analysisC2 transverse foramenFracture patternsFisher's exact testMultiplanar CT scansFracture classification schemeStudent's t-testAntithrombotic treatmentNeurological sequelaeFracture hospitalizationsOccipital fractureDens fracturesTrauma centerScreening for Pediatric Blunt Cerebrovascular Injury: Review of Literature and a Cost-Effectiveness Analysis
Malhotra A, Wu X, Kalra VB, Goodman TR, Schindler J, Forman HP. Screening for Pediatric Blunt Cerebrovascular Injury: Review of Literature and a Cost-Effectiveness Analysis. Journal Of Pediatric Surgery 2015, 50: 1751-1757. PMID: 26546389, DOI: 10.1016/j.jpedsurg.2015.05.005.Peer-Reviewed Original ResearchConceptsBlunt cerebrovascular injuryPediatric blunt cerebrovascular injurySelective computed tomography angiographyComputed tomography angiographyOptimal imaging strategyCost-effectiveness analysisAnticoagulation therapyCerebrovascular injuryManagement of BCVIAppropriate anticoagulation therapyHigh-risk patientsHigh-risk factorsImaging strategiesPossible screening strategiesReview of literatureSelective anticoagulationPediatric patientsAnticoagulation complicationsTomography angiographySystematic reviewPatientsSocietal perspectiveCost-effective strategyData extractionScreening strategy