2019
Management of Unruptured Intracranial Aneurysms in Older Adults: A Cost-effectiveness Analysis.
Malhotra A, Wu X, Forman HP, Matouk CC, Hughes DR, Gandhi D, Sanelli P. Management of Unruptured Intracranial Aneurysms in Older Adults: A Cost-effectiveness Analysis. Radiology 2019, 291: 411-417. PMID: 30888931, DOI: 10.1148/radiol.2019182353.Peer-Reviewed Original ResearchComparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm.
Malhotra A, Wu X, Miller T, Matouk CC, Sanelli P, Gandhi D. Comparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm. Journal Of Neurosurgery 2019, 132: 42-50. PMID: 30641830, DOI: 10.3171/2018.8.jns181080.Peer-Reviewed Original ResearchConceptsPipeline Embolization DeviceStent-assisted coilingRetreatment rateSmall unruptured aneurysmsComparative effectiveness analysisProbabilistic sensitivity analysesUnruptured aneurysmsEndovascular coilingHealth benefitsUse of PEDHigher health benefitsRate of recurrenceFavorable treatment strategyDecision-analytical studyStent-assisted techniquePED placementTreatment modalitiesEffectiveness analysisTreatment strategiesSmall aneurysmsEmbolization DeviceSimple coilingOutcome riskAneurysmsRetreatment
2018
Management of Tiny Unruptured Intracranial Aneurysms: A Comparative Effectiveness Analysis
Malhotra A, Wu X, Forman HP, Matouk CC, Gandhi D, Sanelli P. Management of Tiny Unruptured Intracranial Aneurysms: A Comparative Effectiveness Analysis. JAMA Neurology 2018, 75: 27-34. PMID: 29159405, PMCID: PMC5833486, DOI: 10.1001/jamaneurol.2017.3232.Peer-Reviewed Original ResearchConceptsUnruptured intracranial aneurysmsComparative effectiveness analysisPreventive treatmentAdult patientsAnnual riskIntracranial aneurysmsHealth benefitsFollow-up imagingCurrent clinical practiceBetter health outcomesRisk of ruptureImaging surveillanceTiny aneurysmsMean ageSubarachnoid hemorrhageRoutine treatmentIncidental detectionEffectiveness analysisClinical studiesMAIN OUTCOMEHigh riskGeneral populationPatientsPubMed searchClinical practice
2017
Cost-effectiveness of Magnetic Resonance Imaging in Cervical Spine Clearance of Neurologically Intact Patients With Blunt Trauma
Wu X, Malhotra A, Geng B, Liu R, Abbed K, Forman HP, Sanelli P. Cost-effectiveness of Magnetic Resonance Imaging in Cervical Spine Clearance of Neurologically Intact Patients With Blunt Trauma. Annals Of Emergency Medicine 2017, 71: 64-73. PMID: 28826754, DOI: 10.1016/j.annemergmed.2017.07.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAftercareCervical VertebraeCost-Benefit AnalysisDecision Support TechniquesHealth Care CostsHumansMagnetic Resonance ImagingMarkov ChainsModels, EconomicQuality-Adjusted Life YearsSensitivity and SpecificitySpinal InjuriesTomography, X-Ray ComputedUnited StatesWounds, NonpenetratingConceptsMagnetic resonance imagingCervical computed tomographyBlunt traumaIntact patientsUnstable injuriesCT resultsResonance imagingCost of MRICervical spine clearanceIncidence of patientsPermanent neurologic deficitsHealth benefitsNegative predictive valueProbabilistic sensitivity analysesInitial CT resultsCervical clearanceSpine clearanceNeurologic deficitsHard collarCord injuryPatient populationAlert patientsComputed tomographyPredictive valuePatients