2019
Antigen presentation by CD301b+ dermal dendritic cells dictates CD4+ T cell fate
Tatsumi N, Iwasaki A, Kumamoto Y. Antigen presentation by CD301b+ dermal dendritic cells dictates CD4+ T cell fate. The Journal Of Immunology 2019, 202: 56.9-56.9. DOI: 10.4049/jimmunol.202.supp.56.9.Peer-Reviewed Original ResearchCD4 T cellsOT-II cellsAntigen-specific CD4 T cellsDermal dendritic cellsDendritic cellsMHC class IIT cellsTh2 differentiationAntigen presentationCognate interactionPolyclonal CD4T cellsT cells 7 daysEffector CD4 T cellsT helper type 2 cellsMajor DC subsetsIL-4 productionEpidermal Langerhans cellsCells 7 daysType 2 cellsDC subsetsT cell fateLymph nodesOverall cell cycle progressionLangerhans cellsTh2 cells
1999
Freshly Isolated Peyer's Patch, but Not Spleen, Dendritic Cells Produce Interleukin 10 and Induce the Differentiation of T Helper Type 2 Cells
Iwasaki A, Kelsall B. Freshly Isolated Peyer's Patch, but Not Spleen, Dendritic Cells Produce Interleukin 10 and Induce the Differentiation of T Helper Type 2 Cells. Journal Of Experimental Medicine 1999, 190: 229-240. PMID: 10432286, PMCID: PMC2195574, DOI: 10.1084/jem.190.2.229.Peer-Reviewed Original ResearchConceptsPP dendritic cellsDendritic cellsNaive T cellsPeyer's patchesT cellsIL-10DC populationsImmune responseT cell receptor transgenic miceAllogeneic T cell proliferationT helper type 2 cellsT helper cell responsesMajor histocompatibility complex (MHC) class II moleculesIsolated Peyer's patchesSurface phenotypic analysisVivo dendritic cellsHelper cell responsesIL-10 secretionPrime T cellsDistinct immune responsesReceptor transgenic miceAntigen-presenting cellsIFN-gamma productionProduction of interleukinT cell proliferation