2023
Why we need a deeper understanding of the pathophysiology of long COVID
Iwasaki A, Putrino D. Why we need a deeper understanding of the pathophysiology of long COVID. The Lancet Infectious Diseases 2023, 23: 393-395. PMID: 36967698, PMCID: PMC9928485, DOI: 10.1016/s1473-3099(23)00053-1.Peer-Reviewed Original Research
2022
The immunology and immunopathology of COVID-19
Merad M, Blish CA, Sallusto F, Iwasaki A. The immunology and immunopathology of COVID-19. Science 2022, 375: 1122-1127. PMID: 35271343, DOI: 10.1126/science.abm8108.Peer-Reviewed Original ResearchConceptsImmune responseAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionFatal COVID-19Coronavirus 2 infectionPost-acute sequelaeCOVID-19 pathophysiologyProlongation of symptomsLong COVID syndromeMajor unmet needCOVID-19SARS-CoV-2COVID syndromeDisease resolutionInflammatory processChronic illnessUnmet needDefinitive findingsImmunology researchCOVID-19 researchImmunopathologySequelaePathophysiologySyndrome
2011
Genome–virome interactions: examining the role of common viral infections in complex disease
Foxman EF, Iwasaki A. Genome–virome interactions: examining the role of common viral infections in complex disease. Nature Reviews Microbiology 2011, 9: 254-264. PMID: 21407242, PMCID: PMC3678363, DOI: 10.1038/nrmicro2541.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesAssociation studiesHuman genetic variationLarge regulatory networkHost-virus interactionsCrohn's diseaseRegulatory networksHost genesGenetic variationModel hostGenomic technologiesAutophagy pathwayAntiviral defenseViral infectionAdditional host factorsEnvironmental conditionsComplex diseasesCommon viral infectionsCases of asthmaSubsequent disease developmentGenesHostHost factorsDisease developmentParticular virus