1999
Expression of Surface Antigens During the Differentiation of Human Dendritic Cells vs Macrophages from Blood Monocytes in vitro
Santin A, Hermonat P, Ravaggi M, Chiriva-Internat M, Cannon M, Hiserodt J, Pecorell S, Parham G. Expression of Surface Antigens During the Differentiation of Human Dendritic Cells vs Macrophages from Blood Monocytes in vitro. Immunobiology 1999, 200: 187-204. PMID: 10416127, DOI: 10.1016/s0171-2985(99)80069-2.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, CDAntigens, CD1Antigens, SurfaceB7-1 AntigenB7-2 AntigenCD40 AntigensCD58 AntigensCell AdhesionCell DifferentiationCell DivisionCells, CulturedDendritic CellsGranulocyte-Macrophage Colony-Stimulating FactorHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansImmunoglobulinsImmunophenotypingIntercellular Adhesion Molecule-1Interleukin-4Leukocytes, MononuclearLipopolysaccharide ReceptorsMacrophagesMembrane GlycoproteinsMonocytesT-LymphocytesConceptsDendritic cellsICAM-1 expressionMHC class IIBlood monocytesCostimulation moleculesDay 3Day 10MHC antigensCD14 expressionICAM-1Day 5Majority of DCNaive T cell primingClass IIDifferentiation of DCsProfessional antigen presenting cellsT cell primingHuman dendritic cellsMHC class II moleculesAntigen presenting cellsGM-CSF/ILClass II moleculesMHC class IImportant surface moleculesEarly time points
1998
Radiation‐enhanced expression of E6/E7 transforming oncogenes of human papillomavirus‐16 in human cervical carcinoma
Santin A, Hermonat P, Ravaggi A, Chiriva‐Internati M, Pecorelli S, Parham G. Radiation‐enhanced expression of E6/E7 transforming oncogenes of human papillomavirus‐16 in human cervical carcinoma. Cancer 1998, 83: 2346-2352. PMID: 9840534, DOI: 10.1002/(sici)1097-0142(19981201)83:11<2346::aid-cncr14>3.0.co;2-g.Peer-Reviewed Original ResearchConceptsE6/E7 oncoproteinsMHC class ICervical carcinoma cell linesCarcinoma cell linesCervical carcinomaDose-dependent mannerE6/E7High dosesE7 oncoproteinsSiHa cell lineClass IRadiation therapyMajor histocompatibility complex restriction elementCell linesRadiation-induced drug resistanceHigh-risk HPV genotypesHPV-positive cervical carcinoma cell linesTumor cellsE6/E7 oncogenesE7 oncoprotein expressionE7 viral proteinsHuman papillomavirus infectionImportant risk factorTumor rejection antigensHuman papillomavirus 16Effects of Retinoic Acid Combined with Irradiation on the Expression of Major Histocompatibility Complex Molecules and Adhesion/Costimulation Molecules ICAM-1 in Human Cervical Cancer
Santin A, Hermonat P, Ravaggi A, Chiriva-Internati M, Hiserodt J, Pecorelli S, Parham G. Effects of Retinoic Acid Combined with Irradiation on the Expression of Major Histocompatibility Complex Molecules and Adhesion/Costimulation Molecules ICAM-1 in Human Cervical Cancer. Gynecologic Oncology 1998, 70: 195-201. PMID: 9740690, DOI: 10.1006/gyno.1998.5060.Peer-Reviewed Original ResearchConceptsIntercellular adhesion molecule-1Class II surface antigensICAM-1 antigenSurface antigenMHC class ICervical cancer cellsClass IRetinoic acidCervical cancerHigh dosesUpregulated HLA class ITumor cellsSiHa cervical cancer cellsMajor histocompatibility complex class ICancer cellsHistocompatibility complex class IMajor histocompatibility complex moleculesMolecules ICAM-1Adhesion molecule-1HLA class IICAM-1 moleculesUntreated tumor cellsHuman cervical cancerCervical cancer therapyComplex class I
1997
Effects of irradiation on the expression of major histocompatibility complex class I antigen and adhesion costimulation molecules ICAM-1 in human cervical cancer
Santin A, Hermonat P, Hiserodt J, Chiriva-Internati M, Woodliff J, Theus J, Barclay D, Pecorelli S, Parham G. Effects of irradiation on the expression of major histocompatibility complex class I antigen and adhesion costimulation molecules ICAM-1 in human cervical cancer. International Journal Of Radiation Oncology • Biology • Physics 1997, 39: 737-742. PMID: 9336157, DOI: 10.1016/s0360-3016(97)00372-6.Peer-Reviewed Original ResearchConceptsMHC class ISurface antigenClass IAntigen expressionICAM-1High dosesClass II surface antigensCell linesSiHa cervical cancer cellsMajor histocompatibility complex class IHistocompatibility complex class IICAM-1 antigenMolecules ICAM-1Cell replicationSurface antigen expressionHuman cervical cancerComplex class ICervical cancer cellsCervical carcinoma cell linesCervical cell linesHuman cervical carcinoma cell lineDifferent time pointsCervical cancerCarcinoma cell linesHigh radiation doses
1996
Effects of Irradiation on the Expression of Surface Antigens in Human Ovarian Cancer
Santin A, Hiserodt J, Fruehauf J, DiSaia P, Pecorelli S, Granger G. Effects of Irradiation on the Expression of Surface Antigens in Human Ovarian Cancer. Gynecologic Oncology 1996, 60: 468-474. PMID: 8774659, DOI: 10.1006/gyno.1996.0075.Peer-Reviewed Original ResearchConceptsMHC class ISurface antigenHER2-neuHigh dosesClass IITumor cellsCell linesClass IICAM-1 antigenHuman ovarian cancerHuman ovarian carcinoma cell linesOvarian carcinoma cell linesCA 125Carcinoma cell linesOvarian cancerICAM-1Radiation therapyIrradiation-induced upregulationImmune recognitionTumor tissueAntigenDosesCellsExposureExpression
1995
Development and Characterization of an IL-4-Secreting Human Ovarian Carcinoma Cell Line
Santin A, Ioli G, Hiserodt J, Rose G, Graf M, Tocco L, Lander J, Eck L, Burger R, DiSaia P, Pecorelli S, Granger G. Development and Characterization of an IL-4-Secreting Human Ovarian Carcinoma Cell Line. Gynecologic Oncology 1995, 58: 230-239. PMID: 7622110, DOI: 10.1006/gyno.1995.1216.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, NeoplasmAntigens, SurfaceCell DivisionCell SurvivalClone CellsCystadenocarcinoma, PapillaryDNA, NeoplasmDNA, ViralFemaleGenetic VectorsHistocompatibility Antigens Class IHumansIntercellular Adhesion Molecule-1Interleukin-4KineticsOvarian NeoplasmsPlasmidsRetroviridaeTransduction, GeneticTumor Cells, CulturedVaccinesConceptsHuman ovarian carcinoma cell linesOvarian carcinoma cell linesCarcinoma cell linesInterleukin-4UCI-107Detectable MHC class IICell linesAdvanced ovarian cancerIL-4 secretionMHC class IICytokine interleukin-4IL-4 receptorMHC class ILXSN retroviral vectorOvarian carcinoma cellsIL-4 geneMonths of studyCA 125Ovarian cancerICAM-1Parental cell lineDay 8Vector control cellsClass IIUCI 101