2012
Prognostic Significance of Vascular Endothelial Growth Factor Serum Determination in Women with Ovarian Cancer
Bandiera E, Franceschini R, Specchia C, Bignotti E, Trevisiol C, Gion M, Pecorelli S, Santin AD, Ravaggi A. Prognostic Significance of Vascular Endothelial Growth Factor Serum Determination in Women with Ovarian Cancer. International Scholarly Research Notices 2012, 2012: 245756. PMID: 22792477, PMCID: PMC3390037, DOI: 10.5402/2012/245756.Peer-Reviewed Original ResearchIndependent prognostic factorPrognostic factorsPrognostic significanceOvarian cancerSerum vascular endothelial growth factor (VEGF) levelsVascular endothelial growth factor levelsPresence of ascitesLymph node involvementResidual tumor sizeSubgroup of patientsGood prognostic markerGrowth factor levelsPotential prognostic significanceMEDLINE/PubMedSVEGF levelsFIGO stageNode involvementOverall survivalTumor sizeTumor gradeEligible studiesPatient outcomesPrognostic markerInclusion criteriaPrognostic variables
2010
Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients
Bignotti E, Todeschini P, Calza S, Falchetti M, Ravanini M, Tassi RA, Ravaggi A, Bandiera E, Romani C, Zanotti L, Tognon G, Odicino FE, Facchetti F, Pecorelli S, Santin AD. Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients. European Journal Of Cancer 2010, 46: 944-953. PMID: 20060709, DOI: 10.1016/j.ejca.2009.12.019.Peer-Reviewed Original ResearchConceptsEpithelial ovarian cancerTrop-2 overexpressionTrop-2 expressionOverall survivalPrognostic factorsProtein overexpressionTrop-2 protein expressionMultivariate Cox regression analysisConventional clinicopathological featuresPresence of ascitesCox regression analysisLymph node metastasisOvarian carcinoma patientsPoor overall survivalIndependent prognostic markerNovel prognostic factorUnivariate survival analysisAggressive malignant phenotypeImmunotherapeutic strategiesShort-term cultureCarcinoma patientsClinical courseNode metastasisClinicopathological featuresPrognostic significance