2001
The CA 125 Gene: An Extracellular Superstructure Dominated by Repeat Sequences
O’Brien T, Beard J, Underwood L, Dennis R, Santin A, York L. The CA 125 Gene: An Extracellular Superstructure Dominated by Repeat Sequences. Tumor Biology 2001, 22: 348-366. PMID: 11786729, DOI: 10.1159/000050638.Peer-Reviewed Original ResearchConceptsThreonine-rich sequenceAmino acid repeat unitsShort cytoplasmic tailAmino-terminal domainRepeat unitsTransmembrane domainCytoplasmic tailRepeat domainTerminal domainO-glycosylationBiological functionsRepeat sequencesCytoplasmic phosphorylationEpitope binding sitesExtracellular domainExtracellular structuresCysteine loopProtein coreTransmembrane glycoproteinLarge transmembrane glycoproteinProteolytic cleavageGenesBinding sitesPhysiologic roleSequence
1998
Involvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1.
Kokorina NA, Santin AD, Li C, Hermonat PL. Involvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1. Human Virology 1998, 1: 441-50. PMID: 10195265.Peer-Reviewed Original ResearchConceptsProtein-DNA interactionsDNA binding abilityGene expressionHIV-1 long terminal repeat (LTR) sequencesTATA box regionLong terminal repeat sequencesHIV-LTR DNATerminal repeat sequencesRep78 proteinTranscription initiationTranscription factorsTATA boxRepeat sequencesVirus Rep78Rep78Box regionAmino acidsDNAInhibition of TatLikely targetMechanism of inhibitionMutantsHIV LTRElectrophoretic mobilityBinding