2007
Overexpression of mammaglobin B in epithelial ovarian carcinomas
Tassi RA, Bignotti E, Rossi E, Falchetti M, Donzelli C, Calza S, Ravaggi A, Bandiera E, Pecorelli S, Santin AD. Overexpression of mammaglobin B in epithelial ovarian carcinomas. Gynecologic Oncology 2007, 105: 578-585. PMID: 17343903, DOI: 10.1016/j.ygyno.2007.01.043.Peer-Reviewed Original ResearchConceptsEpithelial ovarian carcinomaHuman ovarian surface epitheliumMammaglobin BOvarian cancerReal-time PCRBenign cystadenomasOvarian carcinomaNormal ovariesNovel ovarian cancer biomarkersB expressionNormal human ovarian surface epitheliumPrimary epithelial ovarian carcinomaSerous papillary ovarian cancerMammaglobin B mRNAMultiple histological typesOvarian cancer biopsiesSerous papillary tumorsClear cell tumorsOvarian surface epitheliumFresh frozen biopsiesOvarian cancer biomarkersParaffin-embedded tissuesMixed histologyBorderline tumorsHistologic type
2006
Overexpression of kallikrein 10 (hK10) in uterine serous papillary carcinomas
Santin AD, Diamandis EP, Bellone S, Marizzoni M, Bandiera E, Palmieri M, Papasakelariou C, Katsaros D, Burnett A, Pecorelli S. Overexpression of kallikrein 10 (hK10) in uterine serous papillary carcinomas. American Journal Of Obstetrics And Gynecology 2006, 194: 1296-1302. PMID: 16647913, DOI: 10.1016/j.ajog.2005.10.794.Peer-Reviewed Original ResearchConceptsUterine serous papillary carcinomaSerous papillary carcinomaPapillary carcinoma patientsCarcinoma patientsEndometrioid carcinomaPapillary carcinomaKallikrein 10Benign diseaseSecretion levelsEndometrioid carcinoma patientsNormal healthy femalesTumor culturesSerous papillary tumorsCell biopsyPrimary endometrioid carcinomaNon-cancer groupExpression levelsReal-time polymerase chain reactionGene expression levelsPrimary tumor culturesAggressive variantHealthy womenCarcinoma cell linesPapillary tumorsEndometrial tumors
2004
Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
Santin AD, Zhan F, Bellone S, Palmieri M, Cane S, Gokden M, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J, Pecorelli S. Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling. British Journal Of Cancer 2004, 90: 1814-1824. PMID: 15208622, PMCID: PMC2409747, DOI: 10.1038/sj.bjc.6601791.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCarcinoma, PapillaryCells, CulturedCystadenocarcinoma, SerousDiagnosis, DifferentialFemaleFlow CytometryGene Expression ProfilingGene Expression Regulation, NeoplasticHumansImmunohistochemistryMiddle AgedOligonucleotide Array Sequence AnalysisOvarian NeoplasmsReceptor, ErbB-2Reverse Transcriptase Polymerase Chain ReactionUterine NeoplasmsConceptsUterine serous papillary carcinomaGene expressionOverexpressed genesSerous papillary carcinomaGene expression fingerprintGene expression profilingHuman genesC-erbB2 geneExpression fingerprintsMolecular basisExpression profilingPapillary carcinomaOligonucleotide microarraysExpression productsQuantitative RT-PCRGenesClinical tissue samplesProbe setsTwo-fold differenceMore effective treatment modalitiesEffective treatment modalitySerous papillary tumorsPlasminogen activator inhibitorDifferent biological behaviorDevelopment of novel