1999
Chromosomal latency and expression at map unit 96 of a wild-type plus adeno-associated virus (AAV)/Neo vector and identification of p81, a new AAV transcriptional promoter.
Hermonat PL, Santin AD, De Greve J, De Rijcke M, Bishop BM, Han L, Mane M, Kokorina N. Chromosomal latency and expression at map unit 96 of a wild-type plus adeno-associated virus (AAV)/Neo vector and identification of p81, a new AAV transcriptional promoter. Human Virology 1999, 2: 359-68. PMID: 10774553.Peer-Reviewed Original Research
1998
Inhibition/Stimulation of Bovine Papillomavirus by Adeno-Associated Virus Is Time as Well as Multiplicity Dependent
Hermonat P, Meyers C, Parham G, Santin A. Inhibition/Stimulation of Bovine Papillomavirus by Adeno-Associated Virus Is Time as Well as Multiplicity Dependent. Virology 1998, 247: 240-250. PMID: 9705917, DOI: 10.1006/viro.1998.9256.Peer-Reviewed Original ResearchThe Adeno-Associated Virus Rep78 Major Regulatory Protein Binds the Cellular TATA-Binding Proteinin Vitroandin Vivo
Hermonat P, Santin A, Batchu R, Zhan D. The Adeno-Associated Virus Rep78 Major Regulatory Protein Binds the Cellular TATA-Binding Proteinin Vitroandin Vivo. Virology 1998, 245: 120-127. PMID: 9614873, DOI: 10.1006/viro.1998.9144.Peer-Reviewed Original ResearchConceptsPossible protein-protein interactionsBasal transcription factorsMajor regulatory proteinTranscription factorsRegulatory proteinsTwo-hybrid systemTranscription initiation complexProtein-protein interactionsNumerous interactionsYeast GAL4Human TATAInitiation complexHeterologous promoterAmino halfRep78Biological roleGene expressionWestern analysisVivo interactionAAV promotersPromoterTATAProteinElectrophoretic mobilityRegulatory abilityInvolvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1.
Kokorina NA, Santin AD, Li C, Hermonat PL. Involvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1. Human Virology 1998, 1: 441-50. PMID: 10195265.Peer-Reviewed Original ResearchConceptsProtein-DNA interactionsDNA binding abilityGene expressionHIV-1 long terminal repeat (LTR) sequencesTATA box regionLong terminal repeat sequencesHIV-LTR DNATerminal repeat sequencesRep78 proteinTranscription initiationTranscription factorsTATA boxRepeat sequencesVirus Rep78Rep78Box regionAmino acidsDNAInhibition of TatLikely targetMechanism of inhibitionMutantsHIV LTRElectrophoretic mobilityBinding
1996
Role of the terminal repeat GAGC trimer, the major Rep78 binding site, in adeno‐associated virus DNA replication
Bishop BM, Santin AD, Quirk JG, Hermonat PL. Role of the terminal repeat GAGC trimer, the major Rep78 binding site, in adeno‐associated virus DNA replication. FEBS Letters 1996, 397: 97-100. PMID: 8941722, DOI: 10.1016/s0014-5793(96)01149-0.Peer-Reviewed Original Research