2006
Immunogenic gangliosides in human ovarian carcinoma
Ravindranath MH, Muthugounder S, Presser N, Selvan SR, Santin AD, Bellone S, Saravanan TS, Morton DL. Immunogenic gangliosides in human ovarian carcinoma. Biochemical And Biophysical Research Communications 2006, 353: 251-258. PMID: 17188646, DOI: 10.1016/j.bbrc.2006.12.001.Peer-Reviewed Original ResearchConceptsOEC patientsAscitic fluidGD1a IgMTotal ganglioside levelsPlasma of patientsOvarian epithelial cancer cell linesExpression of GM3Human ovarian carcinomaEpithelial cancer cell linesCancer cell linesPresence of GM3IgM responseIgM titersOvarian carcinomaPresence of GD1aHealthy volunteersSame patientPatientsSignificant expressionCell linesIgMGD1aTitersPositive correlationGM1b
2004
Increased levels of gangliosides in the plasma and ascitic fluid of patients with advanced ovarian cancer
Santin AD, Ravindranath MH, Bellone S, Muthugounder S, Palmieri M, O'Brien TJ, Roman J, Cannon MJ, Pecorelli S. Increased levels of gangliosides in the plasma and ascitic fluid of patients with advanced ovarian cancer. BJOG An International Journal Of Obstetrics & Gynaecology 2004, 111: 613-618. PMID: 15198791, DOI: 10.1111/j.1471-0528.2004.00142.x.Peer-Reviewed Original ResearchConceptsOvarian cancer patientsAdvanced ovarian cancerAdvanced ovarian cancer patientsNormal female controlsPrimary ovarian cancer cell linesOvarian cancer cell linesCancer patientsCancer cell linesOvarian cancerTotal gangliosidesFemale controlsAscitic fluidUterine carcinoma cell linesCell linesJohn Wayne Cancer InstituteAnti-tumor immune functionGanglioside levelsUterine cancer cell linesLipid-associated sialic acidTotal ganglioside levelsTime of surgeryDepartment of ObstetricsPrimary cervical cancerPrimary ovarian tumorsOvarian tumor cells