1999
Expression of Surface Antigens During the Differentiation of Human Dendritic Cells vs Macrophages from Blood Monocytes in vitro
Santin A, Hermonat P, Ravaggi M, Chiriva-Internat M, Cannon M, Hiserodt J, Pecorell S, Parham G. Expression of Surface Antigens During the Differentiation of Human Dendritic Cells vs Macrophages from Blood Monocytes in vitro. Immunobiology 1999, 200: 187-204. PMID: 10416127, DOI: 10.1016/s0171-2985(99)80069-2.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, CDAntigens, CD1Antigens, SurfaceB7-1 AntigenB7-2 AntigenCD40 AntigensCD58 AntigensCell AdhesionCell DifferentiationCell DivisionCells, CulturedDendritic CellsGranulocyte-Macrophage Colony-Stimulating FactorHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansImmunoglobulinsImmunophenotypingIntercellular Adhesion Molecule-1Interleukin-4Leukocytes, MononuclearLipopolysaccharide ReceptorsMacrophagesMembrane GlycoproteinsMonocytesT-LymphocytesConceptsDendritic cellsICAM-1 expressionMHC class IIBlood monocytesCostimulation moleculesDay 3Day 10MHC antigensCD14 expressionICAM-1Day 5Majority of DCNaive T cell primingClass IIDifferentiation of DCsProfessional antigen presenting cellsT cell primingHuman dendritic cellsMHC class II moleculesAntigen presenting cellsGM-CSF/ILClass II moleculesMHC class IImportant surface moleculesEarly time points
1998
Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer.
Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer. European Journal Of Gynaecological Oncology 1998, 19: 229-33. PMID: 9641219.Peer-Reviewed Original ResearchConceptsHeat shock protein gp96Shock protein gp96Tumor rejection antigensHuman cervical cancerCervical cancerRetinoic acidRejection antigensTumor cellsMajor histocompatibility complex class IPresentation of tumorHistocompatibility complex class IBiologic response modifiersCervical cancer cell linesCo-stimulation moleculesComplex class ICell linesCervical carcinoma cell linesHuman cervical carcinoma cell lineCancer cell linesCarcinoma cell linesHumoral immunityTherapeutic dosesViral antigensResponse modifiersICAM-1
1996
Effects of Irradiation on the Expression of Surface Antigens in Human Ovarian Cancer
Santin A, Hiserodt J, Fruehauf J, DiSaia P, Pecorelli S, Granger G. Effects of Irradiation on the Expression of Surface Antigens in Human Ovarian Cancer. Gynecologic Oncology 1996, 60: 468-474. PMID: 8774659, DOI: 10.1006/gyno.1996.0075.Peer-Reviewed Original ResearchConceptsMHC class ISurface antigenHER2-neuHigh dosesClass IITumor cellsCell linesClass IICAM-1 antigenHuman ovarian cancerHuman ovarian carcinoma cell linesOvarian carcinoma cell linesCA 125Carcinoma cell linesOvarian cancerICAM-1Radiation therapyIrradiation-induced upregulationImmune recognitionTumor tissueAntigenDosesCellsExposureExpression
1995
Development and Characterization of an IL-4-Secreting Human Ovarian Carcinoma Cell Line
Santin A, Ioli G, Hiserodt J, Rose G, Graf M, Tocco L, Lander J, Eck L, Burger R, DiSaia P, Pecorelli S, Granger G. Development and Characterization of an IL-4-Secreting Human Ovarian Carcinoma Cell Line. Gynecologic Oncology 1995, 58: 230-239. PMID: 7622110, DOI: 10.1006/gyno.1995.1216.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, NeoplasmAntigens, SurfaceCell DivisionCell SurvivalClone CellsCystadenocarcinoma, PapillaryDNA, NeoplasmDNA, ViralFemaleGenetic VectorsHistocompatibility Antigens Class IHumansIntercellular Adhesion Molecule-1Interleukin-4KineticsOvarian NeoplasmsPlasmidsRetroviridaeTransduction, GeneticTumor Cells, CulturedVaccinesConceptsHuman ovarian carcinoma cell linesOvarian carcinoma cell linesCarcinoma cell linesInterleukin-4UCI-107Detectable MHC class IICell linesAdvanced ovarian cancerIL-4 secretionMHC class IICytokine interleukin-4IL-4 receptorMHC class ILXSN retroviral vectorOvarian carcinoma cellsIL-4 geneMonths of studyCA 125Ovarian cancerICAM-1Parental cell lineDay 8Vector control cellsClass IIUCI 101