2017
R634W KIT Mutation in an Adult With Systemic Mastocytosis
Astle JM, Rose MG, Racke FK, Tormey CA, Siddon AJ. R634W KIT Mutation in an Adult With Systemic Mastocytosis. Lab Medicine 2017, 48: 253-257. PMID: 28520972, DOI: 10.1093/labmed/lmx026.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiopsyDNA Mutational AnalysisHumansMaleMastocytosis, SystemicMutationProto-Oncogene Proteins c-kitSkinUrticaria Pigmentosa
2015
Pathology Consultation on Gene Mutations in Acute Myeloid Leukemia
Ziai JM, Siddon AJ. Pathology Consultation on Gene Mutations in Acute Myeloid Leukemia. American Journal Of Clinical Pathology 2015, 144: 539-554. PMID: 26386075, DOI: 10.1309/ajcp77zfpuqgygwy.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorDNA Mutational AnalysisGene Expression ProfilingHumansLeukemia, Myeloid, AcuteNucleophosminPathology, ClinicalReferral and ConsultationConceptsAcute myeloid leukemiaMyeloid leukemiaGene mutationsTypes of AMLNormal acute myeloid leukemiaAggressive chemotherapy regimensMinimal residual diseaseChemotherapy regimensDisease courseImmunophenotypic featuresResidual diseaseTherapeutic regimensPatient prognosisPrognostic informationTherapeutic implicationsAML classificationIndividualized approachPathology consultationFatal diseasePrognosisHeterogeneous groupRelevant gene mutationsDiseaseLaboratory evaluationRegimens