2021
PRO-THROMBOTIC SIGNATURE FROM NEUTROPHIL ACTIVATION AND DECREASED ADAMTS13 TO VWF RATIO IS A KEY DRIVER OF CARDIAC INJURY IN HOSPITALIZED PATIENTS WITH COVID-19
Wang S, Pine A, Mankbadi M, Chang C, Madeeva D, Zhang H, Dajani A, Crandall I, Sugeng L, Lee A, Chun H. PRO-THROMBOTIC SIGNATURE FROM NEUTROPHIL ACTIVATION AND DECREASED ADAMTS13 TO VWF RATIO IS A KEY DRIVER OF CARDIAC INJURY IN HOSPITALIZED PATIENTS WITH COVID-19. Journal Of The American College Of Cardiology 2021, 77: 3193. PMID: 34167644, PMCID: PMC8091195, DOI: 10.1016/s0735-1097(21)04548-4.Peer-Reviewed Original Research
2020
VWF/ADAMTS13 Ratios Are Potential Markers of Immunothrombotic Complications in Patients with COVID-19: A Cross-Sectional Study
Madeeva D, Christian J, Goshua G, Chun H, Lee A, Pine A. VWF/ADAMTS13 Ratios Are Potential Markers of Immunothrombotic Complications in Patients with COVID-19: A Cross-Sectional Study. Blood 2020, 136: 34-35. PMCID: PMC8330245, DOI: 10.1182/blood-2020-142917.Peer-Reviewed Original ResearchVWF/ADAMTS13 ratioVon Willebrand factorADAMTS13 ratioVenous thrombosisNeutrophil activationCOVID-19Severe COVID-19 diseaseVWF activityNon-ICU unitsPathogenesis of coagulopathySeverity of coagulopathyAbsolute neutrophil countInstitutional review board approvalMarkers of inflammationIntensive care unitCross-sectional studyPotential therapeutic targetSodium citrate tubesReview board approvalSignificant correlationCOVID-19 diseasePossible mechanistic linkImmune system effectorsNeutrophil indexPertinent patient information