2021
CIDEA expression in SAT from adolescent girls with obesity and unfavorable patterns of abdominal fat distribution
Tarabra E, Nouws J, Vash‐Margita A, Hellerstein M, Shabanova V, McCollum S, Pierpont B, Zhao D, Shulman GI, Caprio S. CIDEA expression in SAT from adolescent girls with obesity and unfavorable patterns of abdominal fat distribution. Obesity 2021, 29: 2068-2080. PMID: 34672413, PMCID: PMC8612981, DOI: 10.1002/oby.23295.Peer-Reviewed Original ResearchConceptsAbdominal fat distributionVisceral adipose tissueCIDEA expressionFat distributionProtein levelsAbdominal SATAdolescent girlsHigher visceral adipose tissueSubcutaneous adipose tissue biopsiesAdipose tissue biopsiesReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionMagnetic resonance imagingWeight gain effectsExpression of CIDEAAdipocyte dysfunctionSAT biopsiesAdipose lipidsInsulin resistanceAdipocyte hypertrophySmall adipocytesAdipose tissueTissue biopsiesUnfavorable patternsStrong inverse correlationSupporting Patient-centered Communication on Adolescent Sexual and Reproductive Health—Perspectives to Build an Appointment Planning Tool
Brault MA, Curry LA, Kershaw T, Singh K, Vash-Margita A, Camenga D. Supporting Patient-centered Communication on Adolescent Sexual and Reproductive Health—Perspectives to Build an Appointment Planning Tool. Journal Of Pediatric And Adolescent Gynecology 2021, 34: 725-731. PMID: 33989800, PMCID: PMC10712738, DOI: 10.1016/j.jpag.2021.04.009.Peer-Reviewed Original ResearchConceptsSRH communicationAdolescent primary care clinicPatient/provider communicationAdolescent gynecology clinicPrimary care clinicsAdolescent girlsReproductive health perspectiveMobile health toolsPatient-centered carePatient-centered communicationFacilitators/barriersClinic visitsGynecology clinicCare clinicsSRH careProvider communicationClinic settingHolistic careContraceptive choicesHealthcare providersHealth toolsReproductive careCareAdolescent SexualHealth perspective
2019
The complex relationship between urinary and defecatory disorders in young and adolescent girls.
Vash-Margita A, Guess MK. The complex relationship between urinary and defecatory disorders in young and adolescent girls. Current Opinion In Obstetrics & Gynecology 2019, 31: 317-324. PMID: 31361608, DOI: 10.1097/gco.0000000000000561.Peer-Reviewed Original ResearchConceptsBladder-bowel dysfunctionDefecatory disordersTreatment strategiesAdolescent girlsComplex pelvic floor disordersLower urinary tract dysfunctionAbnormal bowel habitsFunctional bowel disturbancesUrinary tract dysfunctionOptimal treatment strategyPelvic floor disordersUrinary tract pathologyComprehensive treatment strategyBowel disturbancesBowel habitsPerineal painBowel dysfunctionTract dysfunctionUrinary symptomsUrinary incontinenceTract pathologyPhysical examHealth burdenDisordersPathophysiologyAltered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls
Nouws J, Fitch M, Mata M, Santoro N, Galuppo B, Kursawe R, Narayan D, Vash-Margita A, Pierpont B, Shulman GI, Hellerstein M, Caprio S. Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls. Diabetes 2019, 68: 1168-1177. PMID: 30936147, PMCID: PMC6610014, DOI: 10.2337/db18-1162.Peer-Reviewed Original ResearchConceptsObese adolescent girlsFat distributionFatty liverMetabolic impairmentMature adipocytesAdipose tissueAbdominal fat distributionEctopic fat distributionFemoral adipose tissueType 2 diabetesAdolescent girlsDe novo lipogenesisSubcutaneous adipose tissueVascular cell proliferationUnfavorable phenotypeSubcutaneous abdominalAdipose lipidsInsulin resistanceObese adolescentsUnderlying metabolic alterationsObese girlsHigh riskNovo lipogenesisGluteal depotMetabolic alterations