2018
Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA
Montemayor E, Didychuk A, Yake A, Sidhu G, Brow D, Butcher S. Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA. Nature Communications 2018, 9: 1749. PMID: 29717126, PMCID: PMC5931518, DOI: 10.1038/s41467-018-04145-4.Peer-Reviewed Original ResearchConceptsU6 small nuclear RNASmall nuclear RNAPre-mRNAU6 snRNPPre-mRNA substratePrecursor messenger RNAProtein-protein contactsC-terminal regionSaccharomyces cerevisiaeHeteroheptameric ringMature mRNAActive siteU6 snRNPsMRNA decayNuclear RNAPost-transcriptionallySpliceosomeLsm2Prp24SnRNPMessenger RNARNAMRNAIntronLSm8
2012
Structure of Pisum sativum Rubisco with bound ribulose 1,5‐bisphosphate
Loewen P, Didychuk A, Switala J, Perez-Luque R, Fita I, Loewen M. Structure of Pisum sativum Rubisco with bound ribulose 1,5‐bisphosphate. Acta Crystallographica Section F: Structural Biology Communications 2012, 69: 10-14. PMID: 23295478, PMCID: PMC3539695, DOI: 10.1107/s1744309112047549.Peer-Reviewed Original ResearchConceptsRibulose 1,5-bisphosphateRibulose-1,5-bisphosphate carboxylase/oxygenaseSubstrate ribulose 1,5-bisphosphateHanging-drop vapor diffusionSmall subunit sequenceRibulose-1,5-bisphosphateDiffraction-quality crystalsActive-site conformationActive siteRubisco structureRubiscoClosed conformationHexadecameric complexPisum sativumA-resolutionQuaternary structureGarden peaVapor diffusionX-ray diffraction dataPulse cropsCarboxylase/oxygenaseLys201ConformationSitesDiffraction data