2021
Mortality Among Persons Entering HIV Care Compared With the General U.S. Population : An Observational Study.
Edwards JK, Cole SR, Breger TL, Rudolph JE, Filiatreau LM, Buchacz K, Humes E, Rebeiro PF, D'Souza G, Gill MJ, Silverberg MJ, Mathews WC, Horberg MA, Thorne J, Hall HI, Justice A, Marconi VC, Lima VD, Bosch RJ, Sterling TR, Althoff KN, Moore RD, Saag M, Eron JJ. Mortality Among Persons Entering HIV Care Compared With the General U.S. Population : An Observational Study. Annals Of Internal Medicine 2021, 174: 1197-1206. PMID: 34224262, PMCID: PMC8453103, DOI: 10.7326/m21-0065.Peer-Reviewed Original ResearchConceptsGeneral U.S. populationHIV careU.S. populationNorth American AIDS Cohort CollaborationHIV clinical careObservational cohort studyTreatment of adultsRace/ethnicityCohort CollaborationCause mortalityCohort studyHIV infectionModifiable factorsComparable personsObservational studyClinical careHigh riskGeneral populationSociodemographic factorsHealth StatisticsMortalityHIVKaplan-Meier estimatorCareFive yearsFactors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta‐analysis
Hahn JA, Murnane PM, Vittinghoff E, Muyindike WR, Emenyonu NI, Fatch R, Chamie G, Haberer JE, Francis JM, Kapiga S, Jacobson K, Myers B, Couture MC, DiClemente RJ, Brown JL, So-Armah K, Sulkowski M, Marcus GM, Woolf-King S, Cook RL, Richards VL, Molina P, Ferguson T, Welsh D, Piano MR, Phillips SA, Stewart S, Afshar M, Page K, McGinnis K, Fiellin DA, Justice AC, Bryant K, Saitz R. Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta‐analysis. Alcohol Clinical And Experimental Research 2021, 45: 1166-1187. PMID: 33837975, PMCID: PMC8254773, DOI: 10.1111/acer.14611.Peer-Reviewed Original ResearchConceptsIndividual participant dataUnhealthy alcohol useRace/ethnicitySelf-reported alcohol useAlcohol useBiologic variablesHigher oddsAlcohol consumptionBlood collectionAdvanced liver fibrosisUnhealthy alcohol consumptionIndividual patient dataAUDIT-C scoresAssociation of sexAfrican AmericansHigher BMILiver fibrosisEligible studiesHigher hemoglobinClinical careLower oddsAlcohol metabolitesParticipant dataPatient dataMixed effects models
2018
Brief Report
Yanik EL, Hernández-Ramírez RU, Qin L, Lin H, Leyden W, Neugebauer RS, Horberg MA, Moore RD, Mathews WC, Justice AC, Hessol NA, Mayor AM, Gill MJ, Brooks JT, Sun J, Althoff KN, Engels EA, Silverberg MJ, Dubrow R. Brief Report. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2018, 78: 499-504. PMID: 29771785, PMCID: PMC6037538, DOI: 10.1097/qai.0000000000001719.Peer-Reviewed Original ResearchConceptsMelanoma incidenceAntiretroviral therapyGeneral populationMelanoma riskNorth American AIDS Cohort CollaborationRelationship of immunosuppressionWhite general populationHIV RNA levelsStandardized incidence ratiosCutaneous melanoma incidenceUltraviolet B exposureHigher melanoma incidenceHigh UVB exposureCohort CollaborationSkin surveillanceCD4 countHIV RNAImmune dysfunctionIncidence ratiosCox regressionHIV replicationRisk factorsCalendar periodWhite raceClinical care
2017
Multimorbidity Among Persons Living with Human Immunodeficiency Virus in the United States
Wong C, Gange SJ, Moore RD, Justice AC, Buchacz K, Abraham AG, Rebeiro PF, Koethe JR, Martin JN, Horberg MA, Boyd CM, Kitahata MM, Crane HM, Gebo KA, Gill MJ, Silverberg MJ, Palella FJ, Patel P, Samji H, Thorne J, Rabkin CS, Mayor A, Althoff KN, Freeman A, Cescon A, Rachlis A, Rogers B, Rodriguez B, Grasso C, Benson C, Drozd D, Fiellin D, Haas D, Kirk G, Willig J, Globerman J, Brooks J, Eron J, Montaner J, Gabler K, Anastos K, Mayer K, Jacobson L, Kopansky-Giles M, Klein M, Turner M, Mugavero M, Saag M, Harrigan P, Dubrow R, Hunter-Mellado R, Hogg R, Bosch R, McKaig R, Bebawy S, Rourke S, Napravnik S, Boswell S, Sterling T. Multimorbidity Among Persons Living with Human Immunodeficiency Virus in the United States. Clinical Infectious Diseases 2017, 66: 1230-1238. PMID: 29149237, PMCID: PMC5889007, DOI: 10.1093/cid/cix998.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsBlack PeopleCohort StudiesDiabetes Mellitus, Type 2FemaleHeterosexualityHIVHIV InfectionsHomosexuality, MaleHumansHypercholesterolemiaHypertensionLongitudinal StudiesMaleMiddle AgedMultimorbidityRenal Insufficiency, ChronicSexual and Gender MinoritiesUnited StatesWhite PeopleConceptsHuman immunodeficiency virusAdjusted prevalence ratiosAge-associated conditionsImmunodeficiency virusMultimorbidity prevalenceClinical careNorth American AIDS Cohort CollaborationEnd-stage liver diseaseMedian baseline ageHIV outpatient clinicChronic kidney diseaseRobust error varianceConfidence intervalsComplex healthcare needsDemographic subgroupsCohort CollaborationComorbidity preventionCohort studyDiabetes mellitusLiver diseaseOutpatient clinicKidney diseasePrevalence ratiosBaseline ageCare complexity
2012
Heterogeneity in outcomes of treated HIV-positive patients in Europe and North America: relation with patient and cohort characteristics
May MT, Hogg RS, Justice AC, Shepherd BE, Costagliola D, Ledergerber B, Thiébaut R, Gill MJ, Kirk O, van Sighem A, Saag MS, Navarro G, Sobrino-Vegas P, Lampe F, Ingle S, Guest JL, Crane HM, Monforte A, Vehreschild JJ, Sterne J, Collaboration T. Heterogeneity in outcomes of treated HIV-positive patients in Europe and North America: relation with patient and cohort characteristics. International Journal Of Epidemiology 2012, 41: 1807-1820. PMID: 23148105, PMCID: PMC3535877, DOI: 10.1093/ije/dys164.Peer-Reviewed Original ResearchConceptsCompleteness of ascertainmentHIV-positive patientsAntiretroviral therapyMortality rateAdult HIV-positive patientsPrevious AIDS diagnosisRates of AIDSAdjusted mortality rateMortality rate ratiosHigher mortality riskHigh mortality rateDiverse patient cohortCohort heterogeneityCohort CollaborationPatient characteristicsHIV treatmentAIDS diagnosisPatient cohortAdjusted ratesClinical careMortality riskCohort characteristicsPatientsDeath ascertainmentCohort
2011
Missing Data on the Estimation of the Prevalence of Accumulated Human Immunodeficiency Virus Drug Resistance in Patients Treated With Antiretroviral Drugs in North America
Abraham AG, Lau B, Deeks S, Moore RD, Zhang J, Eron J, Harrigan R, Gill MJ, Kitahata M, Klein M, Napravnik S, Rachlis A, Rodriguez B, Rourke S, Benson C, Bosch R, Collier A, Gebo K, Goedert J, Hogg R, Horberg M, Jacobson L, Justice A, Kirk G, Martin J, McKaig R, Silverberg M, Sterling T, Thorne J, Willig J, Gange SJ, AIDS F. Missing Data on the Estimation of the Prevalence of Accumulated Human Immunodeficiency Virus Drug Resistance in Patients Treated With Antiretroviral Drugs in North America. American Journal Of Epidemiology 2011, 174: 727-735. PMID: 21813792, PMCID: PMC3202147, DOI: 10.1093/aje/kwr141.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusDrug resistanceGenotype testNorth American AIDS Cohort CollaborationHuman immunodeficiency virus drug resistanceGenotypic Resistance Interpretation AlgorithmClinic-based cohortAntiretroviral drug classesAntiretroviral drug resistanceResistance interpretation algorithmsVirus drug resistanceCopies/mLHIV drug resistanceClinical knowledgeDrug resistance mutationsPrevalence of resistanceCohort CollaborationViral loadImmunodeficiency virusAntiretroviral drugsDrug classesClinical carePatientsPrevalenceMultiple imputation methodAssociation of Age and Comorbidity with Physical Function in HIV-Infected and Uninfected Patients: Results from the Veterans Aging Cohort Study
Oursler KK, Goulet JL, Crystal S, Justice AC, Crothers K, Butt AA, Rodriguez-Barradas MC, Favors K, Leaf D, Katzel LI, Sorkin JD. Association of Age and Comorbidity with Physical Function in HIV-Infected and Uninfected Patients: Results from the Veterans Aging Cohort Study. AIDS Patient Care And STDs 2011, 25: 13-20. PMID: 21214375, PMCID: PMC3030913, DOI: 10.1089/apc.2010.0242.Peer-Reviewed Original ResearchConceptsChronic pulmonary diseaseAge-associated comorbiditiesPhysical functionUninfected patientsPulmonary diseaseUninfected subjectsSelf-reported physical functionVeterans Aging Cohort StudyAging of HIVHIV care guidelinesVeterans Aging CohortHIV clinical careAging Cohort StudyAssociation of ageCross-sectional analysisOlder HIVCohort studyHIV infectionHIV statusCare guidelinesPoor functionCardiovascular diseaseClinical carePhysical subscaleHIV
2010
Refill Adherence to Oral Hypoglycemic Agents and Glycemic Control in Veterans
Kim N, Agostini JV, Justice AC. Refill Adherence to Oral Hypoglycemic Agents and Glycemic Control in Veterans. Annals Of Pharmacotherapy 2010, 44: 800-808. PMID: 20388863, PMCID: PMC3117591, DOI: 10.1345/aph.1m570.Peer-Reviewed Original ResearchConceptsOral hypoglycemic agentsGlycemic controlGoal A1CHypoglycemic agentsBaseline dateInadequate diabetes controlPercent of patientsPoor glycemic controlMain outcome measuresBaseline A1CContinuous refillNonpersistent patientsComorbid hypertensionDiabetes medicationsMedian ageBetter persistenceMedication nonadherenceDiabetes controlDays' supplyOutcome measuresClinical careEligible veteransPatientsA1CMedications