2021
Polypharmacy-associated risk of hospitalisation among people ageing with and without HIV: an observational study
Justice AC, Gordon KS, Romero J, Edelman EJ, Garcia BJ, Jones P, Khoo S, Re V, Rentsch CT, Tate JP, Tseng A, Womack J, Jacobson D. Polypharmacy-associated risk of hospitalisation among people ageing with and without HIV: an observational study. The Lancet Healthy Longevity 2021, 2: e639-e650. PMID: 34870254, PMCID: PMC8639138, DOI: 10.1016/s2666-7568(21)00206-3.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyMedication countDrug-drug interactionsAntiretroviral therapyObservational studyPhysiological frailtyVeterans Affairs Health Services ResearchMore drug-drug interactionsRisk of hospitalisationRisk of admissionAging Cohort StudyHIV-1 RNANon-ART medicationsAdverse health outcomesNational InstituteHealth services researchAdditional medicationObserved medicationActive medicationCause mortalityMore medicationsCohort studyPrescription fillsHIV statusPrescription medications
2018
Association of Viral Suppression With Lower AIDS-Defining and Non-AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study.
Park LS, Tate JP, Sigel K, Brown ST, Crothers K, Gibert C, Goetz MB, Rimland D, Rodriguez-Barradas MC, Bedimo RJ, Justice AC, Dubrow R. Association of Viral Suppression With Lower AIDS-Defining and Non-AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study. Annals Of Internal Medicine 2018, 169: 87-96. PMID: 29893768, PMCID: PMC6825799, DOI: 10.7326/m16-2094.Peer-Reviewed Original ResearchConceptsLong-term viral suppressionViral suppressionLong-term suppressionCancer incidenceCancer riskHIV treatment successLow viral suppressionViral suppression statusProspective cohort studyT-cell countsEffect of CD4HIV-positive veteransCancer incidence ratesNational InstituteNational Cancer InstituteAIDS definingNon-AIDSUninfected veteransAntiretroviral therapyExcess cancer riskProspective cohortCohort studyUninfected personsIncidence rateTreatment success
2012
HIV and Aging
High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, Deren S, Effros RB, Gebo K, Goronzy JJ, Justice AC, Landay A, Levin J, Miotti PG, Munk RJ, Nass H, Rinaldo CR, Shlipak MG, Tracy R, Valcour V, Vance DE, Walston JD, Volberding P. HIV and Aging. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2012, 60: s1-s18. PMID: 22688010, PMCID: PMC3413877, DOI: 10.1097/qai.0b013e31825a3668.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsCurrent effective treatmentProgression of diseaseMedian life expectancyYears of ageMaintenance of functionAntiretroviral therapyHIV acquisitionHIV infectionImmune senescenceConcurrent diseasesEffective treatmentHIVHuman studiesRisk behaviorsFunctional measuresAIDS researchKey overarching themesLife expectancyNational InstituteTreatment effectsMultimorbidityAgeInfectionDisease
2008
Workshop on HIV Infection and Aging: What Is Known and Future Research Directions
High K, Effros R, Fletcher C, Gebo K, Halter J, Hazzard W, Horne F, Huebner R, Janoff E, Justice A, Kuritzkes D, Nayfield S, Plaeger S, Schmader K, Ashworth J, Campanelli C, Clayton C, Rada B, Woolard N, High K. Workshop on HIV Infection and Aging: What Is Known and Future Research Directions. Clinical Infectious Diseases 2008, 47: 542-553. PMID: 18627268, PMCID: PMC3130308, DOI: 10.1086/590150.Peer-Reviewed Original ResearchConceptsHIV infectionHuman immunodeficiency virus (HIV) infectionInfectious diseasesImmunodeficiency virus infectionInfectious Diseases SocietyActive antiretroviral treatmentNational InstituteDiseases SocietyAntiretroviral treatmentImmunodeficiency syndromeAdvanced ageChronic diseasesVirus infectionDrug toxicityInfectionSpecialty ProfessorsLife expectancyDiseaseComorbiditiesMedical AssociationHigh-priority topicsTreatmentAssociationAging processPriority topics