2020
Association of OPRM1 Functional Coding Variant With Opioid Use Disorder
Zhou H, Rentsch CT, Cheng Z, Kember RL, Nunez YZ, Sherva RM, Tate JP, Dao C, Xu K, Polimanti R, Farrer LA, Justice AC, Kranzler HR, Gelernter J. Association of OPRM1 Functional Coding Variant With Opioid Use Disorder. JAMA Psychiatry 2020, 77: 1072-1080. PMID: 32492095, PMCID: PMC7270886, DOI: 10.1001/jamapsychiatry.2020.1206.Peer-Reviewed Original ResearchConceptsOpioid use disorderUse disordersMendelian randomization analysisAfrican American individualsMAIN OUTCOMEFunctional coding variantSignificant associationCausal associationRandomization analysisElectronic health record dataCurrent opioid crisisAmerican individualsHealth record dataCognitive performanceInternational Statistical ClassificationRelated Health ProblemsPotential causal associationAmerican controlsEuropean American controlsAfrican-American controlsCoding variantBuprenorphine treatmentOUD diagnosisTobacco smokingNinth Revision
2011
Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications
Wang EA, McGinnis KA, Fiellin DA, Goulet JL, Bryant K, Gibert CL, Leaf DA, Mattocks K, Sullivan LE, Vogenthaler N, Justice AC, for the VACS Project Team. Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications. Journal Of General Internal Medicine 2011, 26: 1012-1018. PMID: 21573882, PMCID: PMC3157515, DOI: 10.1007/s11606-011-1723-8.Peer-Reviewed Original ResearchConceptsHIV-1 RNAHIV disease outcomeLow CD4 countAntiretroviral medicationsBody mass indexCD4 countMass indexDisease outcomeVeterans Aging Cohort StudyPoor virologic responseUnsuppressed viral loadAging Cohort StudyMultivariable logistic regressionAntiretroviral medication adherenceCross-sectional studyFood insecure participantsFood-secure participantsPotential causal associationVirologic responseVirologic suppressionCohort studyHIV diseaseHIV outcomesAdjusted analysisFood insecurity