2024
Impact of Decarceration Plus Alcohol, Substance Use, and Mental Health Screening on Life Expectancies of Black Sexual Minority Men and Black Transgender Women Living With HIV in the United States: A Simulation Study Based on HPTN 061
Feelemyer J, Bershteyn A, Scheidell J, Brewer R, Dyer T, Cleland C, Hucks-Ortiz C, Justice A, Mayer K, Grawert A, Kaufman J, Braithwaite S, Khan M. Impact of Decarceration Plus Alcohol, Substance Use, and Mental Health Screening on Life Expectancies of Black Sexual Minority Men and Black Transgender Women Living With HIV in the United States: A Simulation Study Based on HPTN 061. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024, 95: 283-290. PMID: 38032748, PMCID: PMC10922416, DOI: 10.1097/qai.0000000000003354.Peer-Reviewed Original ResearchConceptsLower life expectancyBlack sexual minority menBlack transgender womenReduce incarcerationSubstance useTransgender WomenIncreased LEVeterans Aging Cohort StudyPsychiatric conditionsMental health screeningLinkage to treatmentDisproportionate rates of incarcerationLife expectancyAging Cohort StudyRates of incarcerationHistory of incarcerationSexual minority menImplementing screeningHealth screeningSubstance use disordersTreatment of psychiatric conditionsPositive screenImprove screeningCohort studyDisproportionate rates
2022
Polypharmacy and medical intensive care unit (MICU) admission and 10-year all-cause mortality risk among hospitalized patients with and without HIV
Gordon KS, Crothers K, Butt AA, Edelman EJ, Gibert C, Pisani MM, Rodriguez-Barradas M, Wyatt C, Justice AC, Akgün KM. Polypharmacy and medical intensive care unit (MICU) admission and 10-year all-cause mortality risk among hospitalized patients with and without HIV. PLOS ONE 2022, 17: e0276769. PMID: 36302039, PMCID: PMC9612570, DOI: 10.1371/journal.pone.0276769.Peer-Reviewed Original ResearchConceptsMedical intensive care unit admissionIntensive care unit admissionCare unit admissionMICU admissionSeverity of illnessHazard ratioHIV statusUnit admissionCause mortalityHospitalized patientsElectronic health record cohortLevel of polypharmacyRetrospective cohort studyCause mortality riskCohort studyHIV infectionCox regressionPolypharmacyMortality riskFiscal year 2009AdmissionPatientsMortalitySubstance useStrong associationPredictive Risk Model for Serious Falls Among Older Persons Living With HIV
Womack JA, Murphy TE, Leo-Summers L, Bates J, Jarad S, Smith AC, Gill TM, Hsieh E, Rodriguez-Barradas MC, Tien PC, Yin MT, Brandt CA, Justice AC. Predictive Risk Model for Serious Falls Among Older Persons Living With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2022, 91: 168-174. PMID: 36094483, PMCID: PMC9470988, DOI: 10.1097/qai.0000000000003030.Peer-Reviewed Original ResearchConceptsMiddle-aged veteransOlder PWHAntiretroviral therapySerious fallsOlder personsVeterans Aging Cohort StudyMeasures of multimorbidityAging Cohort StudyBody mass indexMultivariable logistic regressionPredictive risk modelCohort studyMass indexInjury codesElevated riskGeneral populationSix monthsPWHLogistic regressionPotential predictorsSubstance useRadiology reportsHIVExternal causesVeteransChronic pain and substance use disorders among older sexual minority men living with HIV: Implications for HIV disease management across the HIV care continuum
Taylor SW, McKetchnie SM, Batchelder AW, Justice A, Safren SA, O’Cleirigh C. Chronic pain and substance use disorders among older sexual minority men living with HIV: Implications for HIV disease management across the HIV care continuum. AIDS Care 2022, 35: 614-623. PMID: 35653300, PMCID: PMC9715850, DOI: 10.1080/09540121.2022.2076801.Peer-Reviewed Original ResearchConceptsOlder sexual minority menChronic painOpioid use disorderHigher pain ratingsAlcohol use disorderSexual minority menUse disordersPain ratingsMissed appointmentsHIV disease managementHIV care continuumHIV care appointmentsCross-sectional studyMinority menHIV carePain managementMedication adherenceHigher painCare continuumCritical health issuePainHIVSubstance use behaviorsHealth issuesSubstance use
2021
Brief original report: Does smoking status provide information relevant to screening for other substance use among US adults?
Khan MR, Ban K, Caniglia EC, Edelman JE, Gaither J, Crystal S, Chichetto NE, Young KE, Tate J, Justice AC, Braithwaite RS. Brief original report: Does smoking status provide information relevant to screening for other substance use among US adults? Preventive Medicine Reports 2021, 23: 101483. PMID: 34345578, PMCID: PMC8319511, DOI: 10.1016/j.pmedr.2021.101483.Peer-Reviewed Original ResearchInjection drug useUnhealthy alcohol useTobacco screeningDrug useSubstance useOpioid useStimulant useAlcohol useCrack/cocaine useIllicit opioid useCrack/cocaineTest performance characteristicsFormer smokersCurrent smokingSmoking statusUS adultsLifetime smokingCocaine useSmokingScreening resultsFour-fold decreaseNegative resultsMarijuana usePositive resultsTwo-fold decrease
2020
Does Reducing Drinking in Patients with Unhealthy Alcohol Use Improve Pain Interference, Use of Other Substances, and Psychiatric Symptoms?
Caniglia EC, Stevens ER, Khan M, Young KE, Ban K, Marshall BDL, Chichetto NE, Gaither JR, Crystal S, Edelman EJ, Fiellin DA, Gordon AJ, Bryant KJ, Tate J, Justice AC, Braithwaite RS. Does Reducing Drinking in Patients with Unhealthy Alcohol Use Improve Pain Interference, Use of Other Substances, and Psychiatric Symptoms? Alcohol Clinical And Experimental Research 2020, 44: 2257-2265. PMID: 33030753, PMCID: PMC8077101, DOI: 10.1111/acer.14455.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useAlcohol usePain interferenceTobacco smokingUS veteransOdds ratioPsychiatric symptomsDepressive symptomsCocaine useVeterans Aging Cohort StudyAlcohol Use Disorders Identification Test (AUDIT) questionnaireCannabis useSubstance useAging Cohort StudyAnxiety symptomsSeparate logistic regression modelsChronic pain interferenceMultisite observational studyLogistic regression modelsCohort studyInverse probability weightingNext followObservational studyPotential selection biasYears postbaselineThe OATH Syndemic: opioids and other substances, aging, alcohol, tobacco, and HIV.
Womack JA, Justice AC. The OATH Syndemic: opioids and other substances, aging, alcohol, tobacco, and HIV. Current Opinion In HIV And AIDS 2020, 15: 218-225. PMID: 32487817, PMCID: PMC7422477, DOI: 10.1097/coh.0000000000000635.Peer-Reviewed Original ResearchConceptsSubstance useTreatment of frailtyManagement of HIVAdverse drug interactionsAge-related outcomesPrescribed medicationsHIVHealth statusHealthcare teamFrailtyAdverse effectsSyndemicStigma contributesTreatmentSerious consequencesSubstance interactionsIndividual manifestationsPLWHPolypharmacyOpioidsMedicationsMultimorbidityImportant pathwaySex biasSubstancesPolypharmacy in HIV: recent insights and future directions.
Edelman EJ, Rentsch CT, Justice AC. Polypharmacy in HIV: recent insights and future directions. Current Opinion In HIV And AIDS 2020, 15: 126-133. PMID: 31833963, PMCID: PMC7543953, DOI: 10.1097/coh.0000000000000608.Commentaries, Editorials and LettersConceptsSeverity of illnessInappropriate medicationsDrug interactionsActual adverse eventsSubstance useTotal drug burdenMechanism of injuryElectronic health recordsNonantiretroviral medicationsUpdate findingsMore medicationsAdverse eventsDrug burdenClinical managementPolypharmacyDirect biomarkerMedicationsModifiable mechanismsPWHSicker individualsHealth recordsStrong associationHIVInjuryIllnessInsights Provided by Depression Screening Regarding Pain, Anxiety, and Substance use in a Veteran Population
Stevens ER, Mazumdar M, Caniglia EC, Khan MR, Young KE, Edelman EJ, Gordon AJ, Fiellin DA, Maisto SA, Chichetto NE, Crystal S, Gaither JR, Justice AC, Braithwaite RS. Insights Provided by Depression Screening Regarding Pain, Anxiety, and Substance use in a Veteran Population. Journal Of Primary Care & Community Health 2020, 11: 2150132720949123. PMID: 32772883, PMCID: PMC7418233, DOI: 10.1177/2150132720949123.Peer-Reviewed Original ResearchConceptsPositive predictive valueSubstance useOdds ratioVeterans Aging Cohort Study (VACS) dataPHQ-9 scoresPrimary care settingCohort study dataTest performance characteristicsSymptoms of anxietyMedian ageDepression screeningLikelihood ratio valuesDepression screenPHQ-9Care settingsVeteran populationPredictive valueSignificant associationSymptomsDiagnostic assessmentAnxietyStudy dataAdditional informationAssociationPain
2019
Polypharmacy, Hazardous Alcohol and Illicit Substance Use, and Serious Falls Among PLWH and Uninfected Comparators.
Womack JA, Murphy TE, Rentsch CT, Tate JP, Bathulapalli H, Smith AC, Bates J, Jarad S, Gibert CL, Rodriguez-Barradas MC, Tien PC, Yin MT, Gill TM, Friedlaender G, Brandt CA, Justice AC. Polypharmacy, Hazardous Alcohol and Illicit Substance Use, and Serious Falls Among PLWH and Uninfected Comparators. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82: 305-313. PMID: 31339866, PMCID: PMC7176040, DOI: 10.1097/qai.0000000000002130.Peer-Reviewed Original ResearchConceptsIllicit substance useHazardous alcoholSerious fallsUninfected comparatorsMedication classesOpioid prescriptionsSubstance useHIV statusMuscle relaxantsRisk factorsVeterans Aging Cohort StudyAging Cohort StudyIllicit substance abuseUnconditional logistic regressionNon-ART medicationsHazardous alcohol useSubstance use/abuseCase-control designKey risk factorsUse/abuseCohort studyMedication countInjury codesDuration of observationBaseline dateLife-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- and Alcohol-Related Deaths Using the Lives Saved Simulation Model
Althoff KN, Chandran A, Zhang J, Arevalo WM, Gange SJ, Sterling TR, Gill MJ, Justice AC, Palella FJ, Rebeiro PF, Silverberg MJ, Mayor AM, Horberg MA, Thorne JE, Rabkin CS, Mathews WC, Klein MB, Humes E, Lee J, Hogg R, Moore RD, Research and Design of IeDEA N. Life-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- and Alcohol-Related Deaths Using the Lives Saved Simulation Model. American Journal Of Epidemiology 2019, 188: 2097-2109. PMID: 31602475, PMCID: PMC7036649, DOI: 10.1093/aje/kwz232.Peer-Reviewed Original ResearchConceptsAlcohol-related deathsInjection drug useKey populationsLife expectancyDrug useHuman immunodeficiency virusLife expectancy benefitAge 20 yearsCause of deathCurrent opioid epidemicAlcohol-related mortalityAntiretroviral treatmentImmunodeficiency virusOpioid epidemicExpected life expectancyWhite womenSubstance useWhite menComparison groupDrugsDeathPLWHLife expectancy disparityMenBlack men
2018
Past year and prior incarceration and HIV transmission risk among HIV-positive men who have sex with men in the US*
Khan MR, McGinnis KA, Grov C, Scheidell JD, Hawks L, Edelman EJ, Fiellin DA, McInnes DK, Braithwaite RS, Justice AC, Wang EA. Past year and prior incarceration and HIV transmission risk among HIV-positive men who have sex with men in the US*. AIDS Care 2018, 31: 349-356. PMID: 30064277, PMCID: PMC6699634, DOI: 10.1080/09540121.2018.1499861.Peer-Reviewed Original ResearchConceptsHIV-positive MSMSex risk behaviorsViral loadSubstance useDrug useRisk behaviorsNon-injection drug useTransmission riskMultiple sex partnershipsDetectable viral loadHIV viral loadHIV transmission riskInjection drug useNew HIV infectionsHIV-positive menPrior incarcerationHealth care programsHIV infectionClinical outcomesPast yearCare programSociodemographic factorsSocial determinantsRisk determinantsMSM
2017
Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men
Adams JW, Bryant KJ, Edelman J, Fiellin DA, Gaither JR, Gordon AJ, Gordon KS, Kraemer KL, Mimiaga MJ, Operario D, Tate JP, van den Berg JJ, Justice AC, Marshall BDL. Association of Cannabis, Stimulant, and Alcohol use with Mortality Prognosis Among HIV-Infected Men. AIDS And Behavior 2017, 22: 1341-1351. PMID: 28887669, PMCID: PMC5881942, DOI: 10.1007/s10461-017-1905-4.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyLow-risk alcohol useRisk alcohol useMortality riskAlcohol useStimulant useAdjusted longitudinal analysesAging Cohort StudyUnhealthy alcohol useAssociation of cannabisVACS IndexCause mortalityCohort studyPatient populationPrognostic indicatorMortality prognosisHIVStudy periodSubstance useCannabisRiskLongitudinal analysisMenMortalityStimulants
2016
What are the Patterns Between Depression, Smoking, Unhealthy Alcohol Use, and Other Substance Use Among Individuals Receiving Medical Care? A Longitudinal Study of 5479 Participants
Ruggles KV, Fang Y, Tate J, Mentor SM, Bryant KJ, Fiellin DA, Justice AC, Braithwaite RS. What are the Patterns Between Depression, Smoking, Unhealthy Alcohol Use, and Other Substance Use Among Individuals Receiving Medical Care? A Longitudinal Study of 5479 Participants. AIDS And Behavior 2016, 21: 2014-2022. PMID: 27475945, PMCID: PMC5542002, DOI: 10.1007/s10461-016-1492-9.Peer-Reviewed Original ResearchConceptsUnhealthy alcohol useVeterans Aging Cohort StudyAlcohol useSubstance useTreatment strategiesIntegrated screeningCurrent depressionMedical careHIV-negative subgroupsAging Cohort StudyPatterns of depressionCohort studyCurrent smokingOpioid useNegative subgroupSmokingDepressionLongitudinal studyHIVMarijuana useSubgroupsCareCurrent useScreeningStatus
2015
Momentary assessment of PTSD symptoms and sexual risk behavior in male OEF/OIF/OND Veterans
Black AC, Cooney NL, Justice AC, Fiellin LE, Pietrzak RH, Lazar CM, Rosen MI. Momentary assessment of PTSD symptoms and sexual risk behavior in male OEF/OIF/OND Veterans. Journal Of Affective Disorders 2015, 190: 424-428. PMID: 26551400, PMCID: PMC4684959, DOI: 10.1016/j.jad.2015.10.039.Peer-Reviewed Original ResearchConceptsSexual risk behaviorsPost-traumatic stress disorderRisk behaviorsPTSD symptomsSubstance useEcological momentary assessmentSymptom variabilitySymptom severityFocused clinical interventionsHigh-risk sexual behaviorDaily PTSD symptomsMultiple sexual partnersOEF/OIF/OND veteransSurvey completion ratePTSD measurementMomentary assessmentHIV status and the risk of ischemic stroke among men
Sico J, Chang C, So-Armah K, Justice A, Hylek E, Skanderson M, McGinnis K, Kuller L, Kraemer K, Rimland D, Bidwell Goetz M, Butt A, Rodriguez-Barradas M, Gibert C, Leaf D, Brown S, Samet J, Kazis L, Bryant K, Freiberg M, Chang C, So-Armah K, Justice A, Hylek E, Skanderson M, McGinnis K, Kuller L, Kraemer K, Rimland D, Goetz M, Butt A, Rodriguez Barradas M, Gibert C, Leaf D, Brown S, Samet J, Kazis L, Bryant K, Freiberg M. HIV status and the risk of ischemic stroke among men. Neurology 2015, 84: 1933-1940. PMID: 25862803, PMCID: PMC4433456, DOI: 10.1212/wnl.0000000000001560.Peer-Reviewed Original ResearchConceptsIschemic stroke riskVeterans Aging Cohort Study Virtual CohortIschemic stroke risk factorsStroke risk factorsHIV infectionUninfected veteransIschemic strokeStroke riskMale veteransComorbid diseasesRisk factorsSubstance useBaseline cardiovascular diseaseIschemic stroke rateRace/ethnicityHIV biomarkersMedian followStroke eventsHIV statusCardiovascular diseaseStroke rateClinical sitesHIVInfectionStrokeHIV Infection, Cardiovascular Disease Risk Factor Profile, and Risk for Acute Myocardial Infarction
Paisible AL, Chang CC, So-Armah KA, Butt AA, Leaf DA, Budoff M, Rimland D, Bedimo R, Goetz MB, Rodriguez-Barradas MC, Crane HM, Gibert CL, Brown ST, Tindle HA, Warner AL, Alcorn C, Skanderson M, Justice AC, Freiberg MS. HIV Infection, Cardiovascular Disease Risk Factor Profile, and Risk for Acute Myocardial Infarction. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2015, 68: 209-216. PMID: 25588033, PMCID: PMC4441201, DOI: 10.1097/qai.0000000000000419.Peer-Reviewed Original ResearchConceptsCardiovascular disease risk factorsMajor cardiovascular disease risk factorsAcute myocardial infarctionAMI ratesAMI riskMyocardial infarctionVeterans Aging Cohort Study Virtual CohortCardiovascular disease risk factor profileElevated cardiovascular disease risk factorsTraditional cardiovascular disease risk factorsCardiac healthIncident acute myocardial infarctionRisk of AMIRisk factor profileDisease risk factorsFirst clinical encounterLast followPrevalent CVDHIV infectionRisk factorsFactor profileExclusive profilesVirtual cohortClinical encountersSubstance useTHE ASSOCIATION BETWEEN HIV STATUS AND HOMELESSNESS AMONG VETERANS IN CARE
Ghose T, Gordon A, Metraux S, Mattocks K, Goulet J, Rodriguez‐Barradas M, Day N, Blackstock O, Justice A. THE ASSOCIATION BETWEEN HIV STATUS AND HOMELESSNESS AMONG VETERANS IN CARE. Journal Of Community Psychology 2015, 43: 189-198. DOI: 10.1002/jcop.21673.Peer-Reviewed Original ResearchVeterans Affairs Health Care SystemVeterans Aging Cohort StudyHIV-negative veteransSubstance useAging Cohort StudyAfrican American substance usersGeneral veteran populationHIV-positive statusHazardous alcohol useHealth care systemCohort studyHIV infectionHIV-positiveHIV statusHigh riskVeteran populationWomen veteransHIVAlcohol useCare systemSubstance usersHomelessness riskLast monthVeteransHomelessness prevalenceDrinking trajectories among HIV-infected men who have sex with men: A cohort study of United States veterans
Marshall BD, Operario D, Bryant KJ, Cook RL, Edelman EJ, Gaither JR, Gordon AJ, Kahler CW, Maisto SA, McGinnis KA, van den Berg JJ, Zaller ND, Justice AC, Fiellin DA. Drinking trajectories among HIV-infected men who have sex with men: A cohort study of United States veterans. Drug And Alcohol Dependence 2015, 148: 69-76. PMID: 25596785, PMCID: PMC4330114, DOI: 10.1016/j.drugalcdep.2014.12.023.Peer-Reviewed Original ResearchConceptsHazardous alcohol useGeneralized estimates equationsAlcohol useCohort studyVeterans Aging Cohort StudyMean AUDIT-C scoreInfectious disease clinicAging Cohort StudyAlcohol-related diagnosesAUDIT-C scoresAlcohol use trajectoriesConcurrent substance useGroup-based trajectory modelsDisease clinicMean ageEight-year study periodUS veteransMultivariable modelModifiable targetsSelf-report assessmentsHIVAlcohol consumptionUse trajectoriesStudy periodSubstance use
2013
HIV Infection and the Risk of Acute Myocardial Infarction
Freiberg MS, Chang CC, Kuller LH, Skanderson M, Lowy E, Kraemer KL, Butt AA, Goetz M, Leaf D, Oursler KA, Rimland D, Barradas M, Brown S, Gibert C, McGinnis K, Crothers K, Sico J, Crane H, Warner A, Gottlieb S, Gottdiener J, Tracy RP, Budoff M, Watson C, Armah KA, Doebler D, Bryant K, Justice AC. HIV Infection and the Risk of Acute Myocardial Infarction. JAMA Internal Medicine 2013, 173: 614-622. PMID: 23459863, PMCID: PMC4766798, DOI: 10.1001/jamainternmed.2013.3728.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusAcute myocardial infarctionRisk of AMIFramingham risk factorsUninfected veteransRisk factorsMyocardial infarctionAMI eventsHIV statusVeterans Aging Cohort Study Virtual CohortHIV-1 RNA levelsStandard Framingham risk factorsIncident acute myocardial infarctionIncidence of AMISubstance useBaseline cardiovascular diseaseCD4 cell countHepatitis C infectionBody mass indexHIV-1 RNACopies/mLHIV-positive veteransTime-updated analysisDecade of ageRace/ethnicity