2021
Circulating CD4+ TEMRA and CD4+ CD28− T cells and incident diabetes among persons with and without HIV
Bailin SS, Kundu S, Wellons M, Freiberg MS, Doyle MF, Tracy RP, Justice AC, Wanjalla CN, Landay AL, So-Armah K, Mallal S, Kropski JA, Koethe JR. Circulating CD4+ TEMRA and CD4+ CD28− T cells and incident diabetes among persons with and without HIV. AIDS 2021, 36: 501-511. PMID: 34860194, PMCID: PMC8881388, DOI: 10.1097/qad.0000000000003137.Peer-Reviewed Original ResearchConceptsT cell subsetsIncident diabetesT cellsVeterans Aging Cohort StudyPeripheral mononuclear blood cellsIncident diabetes diagnosisPrevalent diabetes mellitusT effector memoryHIV-negative personsHIV-negative individualsTraditional risk factorsAging Cohort StudyCD28- T cellsSenescent T cellsT cell populationsProportional hazards modelMononuclear blood cellsHigh baseline frequencyCytomegalovirus serostatusCirculating CD4Chart reviewCohort studyEffector memoryInflammatory biomarkersMemory CD4
2019
343. T-cell Subsets Associated with Diabetes in Veterans with and without HIV
Bailin S, McGinnis K, McDonnell W, So-Armah K, Wellons M, Doyle M, Mallal S, Justice A, Freiberg M, Koethe J. 343. T-cell Subsets Associated with Diabetes in Veterans with and without HIV. Open Forum Infectious Diseases 2019, 6: s182-s183. PMCID: PMC6810455, DOI: 10.1093/ofid/ofz360.416.Peer-Reviewed Original ResearchVeterans Aging Cohort StudyT cell subsetsPrevalent diabetesT cellsHIV statusMemory CD4Immune activationNaïve CD8VA electronic medical recordsMultivariate logistic regression modelAdaptive immune activationAdaptive immune profileT effector memoryChronic immune activationEffector memory cellsAging Cohort StudyCentral memory cellsMemory T cellsBody mass indexICD-9 codesPeripheral mononuclear cellsUnhealthy alcohol useElectronic medical recordsLogistic regression modelsRace/ethnicity