2014
End-Stage Renal Disease Among HIV-Infected Adults in North America
Abraham A, Althoff K, Jing Y, Estrella M, Kitahata M, Wester C, Bosch R, Crane H, Eron J, Gill M, Horberg M, Justice A, Klein M, Mayor A, Moore R, Palella F, Parikh C, Silverberg M, Golub E, Jacobson L, Napravnik S, Lucas G, AIDS F, Kirk G, Benson C, Bosch R, Collier A, Boswell S, Grasso C, Mayer K, Hogg R, Harrigan R, Montaner J, Cescon A, Brooks J, Buchacz K, Gebo K, Moore R, Moore R, Carey J, Rodriguez B, Horberg M, Silverberg M, Thorne J, Goedert J, Jacobson L, Klein M, Rourke S, Burchell A, Rachlis A, Hunter-Mellado R, Mayor A, Gill M, Deeks S, Martin J, Saag M, Mugavero M, Willig J, Eron J, Napravnik S, Kitahata M, Crane H, Justice A, Dubrow R, Fiellin D, Sterling T, Haas D, Bebawy S, Turner M, Gange S, Anastos K, Moore R, Saag M, Gange S, Althoff K, Kitahata M, McKaig R, Justice A, Freeman A, Moore R, Freeman A, Lent C, Kitahata M, Van Rompaey S, Crane H, Webster E, Morton L, Simon B, Gange S, Althoff K, Abraham A, Lau B, Zhang J, Jing J, Golub E, Modur S, Hanna D, Rebeiro P, Wong C, Mendes A. End-Stage Renal Disease Among HIV-Infected Adults in North America. Clinical Infectious Diseases 2014, 60: 941-949. PMID: 25409471, PMCID: PMC4357817, DOI: 10.1093/cid/ciu919.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseSex-standardized incidence ratiosRisk of ESRDDiabetes mellitusESRD casesBlack racePredictors of ESRDNorth American AIDS Cohort CollaborationHepatitis C virus coinfectionC virus coinfectionESRD risk factorsIncident ESRD casesHuman immunodeficiency virusHigh viral loadMajority of casesCohort CollaborationVirologic suppressionESRD incidencePrior AIDSRenal transplantViral suppressionInject drugsRenal diseaseVirus coinfectionBlack patients
2011
Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications
Wang EA, McGinnis KA, Fiellin DA, Goulet JL, Bryant K, Gibert CL, Leaf DA, Mattocks K, Sullivan LE, Vogenthaler N, Justice AC, for the VACS Project Team. Food Insecurity is Associated with Poor Virologic Response among HIV-Infected Patients Receiving Antiretroviral Medications. Journal Of General Internal Medicine 2011, 26: 1012-1018. PMID: 21573882, PMCID: PMC3157515, DOI: 10.1007/s11606-011-1723-8.Peer-Reviewed Original ResearchConceptsHIV-1 RNAHIV disease outcomeLow CD4 countAntiretroviral medicationsBody mass indexCD4 countMass indexDisease outcomeVeterans Aging Cohort StudyPoor virologic responseUnsuppressed viral loadAging Cohort StudyMultivariable logistic regressionAntiretroviral medication adherenceCross-sectional studyFood insecure participantsFood-secure participantsPotential causal associationVirologic responseVirologic suppressionCohort studyHIV diseaseHIV outcomesAdjusted analysisFood insecurity
2009
Effect of Baseline CD4 Cell Counts on the Clinical Significance of Short-Term Immunologic Response to Antiretroviral Therapy in Individuals With Virologic Suppression
Moore DM, Harris R, Lima V, Hogg B, May M, Yip B, Justice A, Mocroft A, Reiss P, Lampe F, Chêne G, Costagliola D, Elzi L, Mugavero MJ, Monforte AD, Sabin C, Podzamczer D, Fätkenheuer G, Staszewski S, Gill J, Sterne JA. Effect of Baseline CD4 Cell Counts on the Clinical Significance of Short-Term Immunologic Response to Antiretroviral Therapy in Individuals With Virologic Suppression. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2009, 52: 357-363. PMID: 19668084, PMCID: PMC3032437, DOI: 10.1097/qai.0b013e3181b62933.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyCD4 cell countBaseline CD4 cell countBaseline CD4 countCD4 countImmunologic responseVirologic suppressionCell countAntiretroviral therapyAbsolute CD4Absolute CD4 cell countCD4 cell count strataAdequate immunologic responseART Cohort CollaborationClear therapeutic goalsTreatment-naive individualsCell count strataCART initiationCohort CollaborationCD4 changeHazard ratioViral loadEligible participantsSubsequent prognosisClinical significanceHIV infection in the elderly
Gebo KA, Justice A. HIV infection in the elderly. Current Infectious Disease Reports 2009, 11: 246-254. PMID: 19366568, PMCID: PMC3129647, DOI: 10.1007/s11908-009-0036-0.Peer-Reviewed Original ResearchOlder patientsYounger patientsBetter virologic suppressionOlder HIV patientsActive antiretroviral therapyManagement of HIVPrevalence of HIVDrug-drug interactionsAntiretroviral regimenHAART initiationHAART regimenVirologic suppressionAntiretroviral therapyHIV patientsImmunologic benefitsHIV infectionPatientsSide effectsHIVPopulation agesRegimenAgeHAARTComorbiditiesTherapy