2020
Polypharmacy in HIV: recent insights and future directions.
Edelman EJ, Rentsch CT, Justice AC. Polypharmacy in HIV: recent insights and future directions. Current Opinion In HIV And AIDS 2020, 15: 126-133. PMID: 31833963, PMCID: PMC7543953, DOI: 10.1097/coh.0000000000000608.Commentaries, Editorials and LettersConceptsSeverity of illnessInappropriate medicationsDrug interactionsActual adverse eventsSubstance useTotal drug burdenMechanism of injuryElectronic health recordsNonantiretroviral medicationsUpdate findingsMore medicationsAdverse eventsDrug burdenClinical managementPolypharmacyDirect biomarkerMedicationsModifiable mechanismsPWHSicker individualsHealth recordsStrong associationHIVInjuryIllness
2014
Guideline-Concordant Management of Opioid Therapy Among Human Immunodeficiency Virus (HIV)-Infected and Uninfected Veterans
Gaither JR, Goulet JL, Becker WC, Crystal S, Edelman EJ, Gordon K, Kerns RD, Rimland D, Skanderson M, Weisberg DF, Justice AC, Fiellin DA. Guideline-Concordant Management of Opioid Therapy Among Human Immunodeficiency Virus (HIV)-Infected and Uninfected Veterans. Journal Of Pain 2014, 15: 1130-1140. PMID: 25152300, PMCID: PMC4253900, DOI: 10.1016/j.jpain.2014.08.004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidChronic PainFemaleGuideline AdherenceHIV InfectionsHumansMalePractice Patterns, Physicians'Primary Health CareUnited StatesVeteransConceptsCurrent substance use disorderGuideline-concordant careOpioid therapyUrine drug testsHuman immunodeficiency virusSubstance use disordersUninfected patientsImmunodeficiency virusUse disordersPatient/provider characteristicsPrimary care provider visitsVeterans Affairs/DepartmentGuideline-concordant managementDrug testsCare concordantGuideline concordanceUninfected veteransProvider visitsPatient characteristicsPatient groupPrimary careClinical guidelinesPain medicineProvider characteristicsPatients
2010
Patient and Provider-Reported Symptoms in the Post-cART Era
Edelman EJ, Gordon K, Justice AC. Patient and Provider-Reported Symptoms in the Post-cART Era. AIDS And Behavior 2010, 15: 853-861. PMID: 20490910, PMCID: PMC3118476, DOI: 10.1007/s10461-010-9706-z.Peer-Reviewed Original ResearchConceptsPatient-reported symptomsPost-cART eraClinical outcomesVeterans Aging Cohort StudyAging Cohort StudyHealth-related qualityBaseline survey dataCohort studySymptoms patientsHigh burdenSecondary analysisSymptomsPatientsPrimary providersGold standardKappa scoresHospitalizationRegression analysisMortalityOutcomesProvidersPoor agreementHRQoLHIVPrevalence
2009
Development of an Electronic Medical Record-Based Clinical Decision Support Tool to Improve HIV Symptom Management
Nader CM, Tsevat J, Justice AC, Mrus JM, Levin F, Kozal MJ, Mattocks K, Farber S, Rogers M, Erdos J, Brandt C, Kudel I, Braithwaite R. Development of an Electronic Medical Record-Based Clinical Decision Support Tool to Improve HIV Symptom Management. AIDS Patient Care And STDs 2009, 23: 521-529. PMID: 19538046, PMCID: PMC3048777, DOI: 10.1089/apc.2008.0209.Peer-Reviewed Original ResearchMeSH KeywordsAdultDecision Making, Computer-AssistedDecision Support Systems, ClinicalFemaleHIV InfectionsHumansMaleMedical Records Systems, ComputerizedMiddle AgedPatient SatisfactionPilot ProjectsPractice Guidelines as TopicPractice Patterns, Physicians'Severity of Illness IndexSurveys and QuestionnairesUnited StatesUnited States Department of Veterans AffairsConceptsClinical decision support toolVeterans Health Administration electronic medical recordsElectronic medical recordsSymptom managementMedical recordsProvider awarenessProgress notesClinical HIV careHIV symptom managementEMR notesHIV careHIV clinicClinical responseControl patientsHIV diseaseCommon symptomsPoint of careHIV symptomsProvider notesPatients' perceptionsIntervention groupIntervention periodCare plansPatientsSymptomsThe Association Between the Receipt of Lipid Lowering Therapy and HIV Status Among Veterans Who Met NCEP/ATP III Criteria for the Receipt of Lipid Lowering Medication
Freiberg MS, Leaf DA, Goulet JL, Goetz MB, Oursler KK, Gibert CL, Rodriguez-Barradas MC, Butt AA, Justice AC. The Association Between the Receipt of Lipid Lowering Therapy and HIV Status Among Veterans Who Met NCEP/ATP III Criteria for the Receipt of Lipid Lowering Medication. Journal Of General Internal Medicine 2009, 24: 334-340. PMID: 19127386, PMCID: PMC2642578, DOI: 10.1007/s11606-008-0891-7.Peer-Reviewed Original ResearchConceptsNCEP/ATP III criteriaATP III criteriaHIV viral loadViral loadAdult Treatment Panel guidelinesHigher HIV viral loadFive-site studyLipid lowering medicationsVeterans Aging CohortHIV infection statusLipid-Lowering TherapyProspective observational cohortCross-sectional analysisHIV-HCVLowering therapiesModifiable mediatorsObservational cohortResultsThe prevalenceHIV infectionHIV statusPharmacy dataCardiovascular diseasePanel guidelinesMAIN OUTCOMELow prevalence
2005
Differences between Infectious Diseases—Certified Physicians and General Medicine—Certified Physicians in the Level of Comfort with Providing Primary Care to Patients
Fultz SL, Goulet JL, Weissman S, Rimland D, Leaf D, Gibert C, Rodriguez-Barradas MC, Justice AC. Differences between Infectious Diseases—Certified Physicians and General Medicine—Certified Physicians in the Level of Comfort with Providing Primary Care to Patients. Clinical Infectious Diseases 2005, 41: 738-743. PMID: 16080098, DOI: 10.1086/432621.Peer-Reviewed Original ResearchMeSH KeywordsData CollectionEducation, MedicalHIV InfectionsHumansMedicinePhysiciansPractice Patterns, Physicians'Professional CompetenceSpecializationSurveys and QuestionnairesConceptsID clinicComorbid conditionsActive antiretroviral therapyInfectious disease clinicCommon comorbid conditionsHuman immunodeficiency virusGeneral medical clinicLevel of comfortAntiretroviral therapyComorbid diseasesDisease clinicSuch patientsSelf-reported comfortImmunodeficiency virusPrimary careHIV medicinePrescribing medicationsSubstantial prevalencePatientsPhysician levelClinicMedical clinicsGeneralist physiciansHypertensionHyperlipidemia
2001
Patient- and provider-reported adherence toward a clinically useful approach to measuring antiretroviral adherence
Wagner JH, Justice AC, Chesney M, Sinclair G, Weissman S, Rodriguez-Barradas M, Team F. Patient- and provider-reported adherence toward a clinically useful approach to measuring antiretroviral adherence. Journal Of Clinical Epidemiology 2001, 54: s91-s98. PMID: 11750214, DOI: 10.1016/s0895-4356(01)00450-4.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestViral loadProvider assessmentCurrent drug useDepressive symptomsCurrent alcohol usePatient reportsDrug useAlcohol useIndependent associationVeterans Affairs Health Care SystemPatient-reported adherenceCurrent viral loadPharmacy refill dataAntiretroviral medication adherenceEpidemiological Studies DepressionIllicit drug useDisorders Identification TestElectronic laboratory dataHealth care systemRefill dataMedication adherencePatient adherenceAntiretroviral adherenceMultivariate regression modelClinical Importance of Provider-Reported HIV Symptoms Compared With Patient-Report
Justice AC, Chang CH, Rabeneck L, Zackin S. Clinical Importance of Provider-Reported HIV Symptoms Compared With Patient-Report. Medical Care 2001, 39: 397-408. PMID: 11329526, DOI: 10.1097/00005650-200104000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHIV InfectionsHIV-1HumansMalePractice Patterns, Physicians'Quality of LifeSelf-AssessmentConceptsPatient-reported symptomsHIV-1 RNA levelsCD4 cell countRecent hospitalizationCell countSymptom ChecklistAdverse drug event monitoringRNA levelsCombination antiviral therapyHealth-related qualityPhysical health scalesHIV diseaseHIV infectionAntiviral therapyHRQOL subscalesMulticenter studyHIV symptomsClinical managementPatient reportsHospitalizationPatientsClinical importanceHealth ScaleSecondary analysisSymptoms
1999
Sensitivity, specificity, reliability, and clinical validity of provider-reported symptoms: a comparison with self-reported symptoms. Outcomes Committee of the AIDS Clinical Trials Group.
Justice AC, Rabeneck L, Hays RD, Wu AW, Bozzette SA. Sensitivity, specificity, reliability, and clinical validity of provider-reported symptoms: a comparison with self-reported symptoms. Outcomes Committee of the AIDS Clinical Trials Group. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1999, 21: 126-33. PMID: 10360804.Peer-Reviewed Original ResearchConceptsFunctional statusSymptom SurveyTest-retest reliabilityGlobal qualitySeverity scoreClinical validitySymptom measurementAIDS Clinical Trials GroupAdvanced HIV infectionSelf-reported symptom severityClinical Trials GroupSeverity of symptomsSymptom survey dataSelf-reported symptomsHIV infectionTreatment armsSymptom assessmentOutcomes CommitteeTrial groupSecondary data analysisPoor test-retest reliabilityHIV researchSymptom dataSymptom severitySymptoms