2020
Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2
Salinas YD, Wang Z, DeWan AT. Discovery and Mediation Analysis of Cross-Phenotype Associations Between Asthma and Body Mass Index in 12q13.2. American Journal Of Epidemiology 2020, 190: 85-94. PMID: 32700739, PMCID: PMC7784522, DOI: 10.1093/aje/kwaa144.Peer-Reviewed Original ResearchConceptsBody mass indexMass indexComorbidity of asthmaWhite British subjectsCross-phenotype associationsAdult asthmaAsthma diagnosisAsthmaConfounder adjustmentAsthma associationsBMI associationsMediation analysisLimited evidenceCandidate gene studiesBMIObesityUK BiobankAssociationDiagnosisTwin studiesAgeFurther characterizationComorbiditiesConfounders
2012
Whole-exome sequencing of a pedigree segregating asthma
DeWan AT, Egan KB, Hellenbrand K, Sorrentino K, Pizzoferrato N, Walsh KM, Bracken MB. Whole-exome sequencing of a pedigree segregating asthma. BMC Medical Genomics 2012, 13: 95. PMID: 23046476, PMCID: PMC3563469, DOI: 10.1186/1471-2350-13-95.Peer-Reviewed Original ResearchConceptsNon-asthmatic childrenWhole-exome sequencingAsthma candidate genesAsthmatic childrenAsthmaAsthma associationsAffected motherExome sequencingUnaffected fatherAsthma-susceptibility variantsPrediction scoreUnaffected offspringCommon risk variantsRisk variantsCandidate genesChildrenNonsynonymous variantsAffected offspring