2022
Prediction of Adverse Pathology at Radical Prostatectomy in Grade Group 2 and 3 Prostate Biopsies Using Machine Learning.
Paulson N, Zeevi T, Papademetris M, Leapman MS, Onofrey JA, Sprenkle PC, Humphrey PA, Staib LH, Levi AW. Prediction of Adverse Pathology at Radical Prostatectomy in Grade Group 2 and 3 Prostate Biopsies Using Machine Learning. JCO Clinical Cancer Informatics 2022, 6: e2200016. PMID: 36179281, DOI: 10.1200/cci.22.00016.Peer-Reviewed Original ResearchConceptsGrade group 2Prostate biopsyRadical prostatectomyAdverse outcomesGroup 2GG-2Core prostate biopsyProstate cancer outcomesPatient's clinical riskClinical risk assessmentCore needle biopsyOngoing clinical needAdverse outcome predictionRetrospective reviewAdverse pathologyCAPRA scoreEntire cohortCancer outcomesPathologic diagnosisNeedle biopsyClinical riskDisease outcomeProstate cancerBiopsyDisease one
2021
Extent of High-Grade Prostatic Adenocarcinoma in Multiparametric Magnetic Resonance Imaging-Targeted Biopsy Enhances Prediction of Pathologic Stage.
Paulson N, Vollmer RT, Humphrey PA, Sprenkle PC, Onofrey J, Huber S, Amirkhiz K, Levi AW. Extent of High-Grade Prostatic Adenocarcinoma in Multiparametric Magnetic Resonance Imaging-Targeted Biopsy Enhances Prediction of Pathologic Stage. Archives Of Pathology & Laboratory Medicine 2021, 146: 201-204. PMID: 34015819, DOI: 10.5858/arpa.2020-0568-oa.Peer-Reviewed Original ResearchConceptsMpMRI-targeted biopsiesHigh-grade prostatic adenocarcinomaMultiparametric magnetic resonance imagingHG PCaRadical prostatectomyHigh-grade groupMagnetic resonance imagingPathologic stageRP outcomesProstatic adenocarcinomaGrade Group 2 diseaseResonance imagingGrade groupProstate-confined diseaseSeminal vesicle involvementLymph node metastasisHigher pathologic stageAdditional predictive valueLogistic regression modelsLinear millimeterNode metastasisRetrospective reviewAdverse outcomesTargeted biopsiesProstate biopsy
2004
Urinary bladder biopsy with denuded mucosa: Denuding cystitis—Cytopathologic correlates
Parwani AV, Levi AW, Epstein JI, Ali SZ. Urinary bladder biopsy with denuded mucosa: Denuding cystitis—Cytopathologic correlates. Diagnostic Cytopathology 2004, 30: 297-300. PMID: 15108225, DOI: 10.1002/dc.10406.Peer-Reviewed Original ResearchConceptsHigh-grade urothelial carcinomaUrothelial carcinomaUrinary cytologyFollowing histologic subtypesUrinary bladder biopsiesPositive urinary cytologySurgical pathology filesInvasive urothelial carcinomaOptimal patient managementRecurrent urothelial carcinomaJohns Hopkins HospitalPatient agePathology filesHistologic subtypeBladder biopsiesHistologic diagnosisBladder mucosaFlat carcinomaSensitive modalityPatient managementCytologic diagnosisCystitisCytologic studyTissue biopsiesPatients
2001
CLINICAL SIGNIFICANCE OF DENUDED UROTHELIUM IN BLADDER BIOPSY
LEVI A, POTTER S, SCHOENBERG M, EPSTEIN J. CLINICAL SIGNIFICANCE OF DENUDED UROTHELIUM IN BLADDER BIOPSY. Journal Of Urology 2001, 166: 457-460. PMID: 11458047, DOI: 10.1016/s0022-5347(05)65963-0.Peer-Reviewed Original ResearchConceptsCold cup biopsyHistory of carcinomaCup biopsyBladder biopsiesSubsequent carcinomaPertinent clinical featuresTissue fragmentsLow-grade papillary tumorsSpecific pathological featuresDiagnosis of carcinomaBenign urothelial cellsCystoscopic impressionPatients 22Intravesical chemotherapyClinical featuresBladder lesionsBladder neoplasmsPredictive factorsLoop biopsyPapillary tumorsPathological featuresTissue inflammationBladder carcinomaEpithelial denudationMiscellaneous conditions