2017
Should Cancer Centers start their own specialty pharmacy? Quality and economic data from the oral chemotherapy program at Smilow Cancer Hospital and Yale New Haven Health System.
Adelson K, Stutsky M, Fradkin M, Harrison M, Abdelghany O, Morrow B, Smith M, Havriliak R, Kregling S, Lyons C, Chiang A, Cohen H. Should Cancer Centers start their own specialty pharmacy? Quality and economic data from the oral chemotherapy program at Smilow Cancer Hospital and Yale New Haven Health System. Journal Of Clinical Oncology 2017, 35: 108-108. DOI: 10.1200/jco.2017.35.8_suppl.108.Peer-Reviewed Original ResearchMedication assistance programsOral chemotherapy programChemotherapy programSpecialty pharmacyYale New Haven Health SystemHealth systemClinical oncology pharmacistSmilow Cancer HospitalPatient assistance programsMultidisciplinary task forceSpecialty pharmacistsCollaborative Improvement ModelHealth-system pharmacyOral chemotherapyCancer HospitalCancer CenterOncologic therapyPrescription errorsOncology pharmacistsTreatment protocolHigh riskPatient callsSpecialty servicesOncologic processesDay 1
2014
1473P Phase 1B Trial of Anti-Notch 2/3 Antibody Omp-59R5 in Combination with Etoposide and Cisplatin (Ep) in Patients (Pts) with Untreated Extensive-Stage Small-Cell Lung Cancer (Ed-Sclc): the Pinnacle Study
Pietanza M, Spira A, Jotte R, Gadgeel S, Mita A, Liu S, Gluck W, Kalemkerian G, Chiang A, Hart L, Kapoun A, Xu L, Hill D, Zhou L, Dupont J, Spigel D. 1473P Phase 1B Trial of Anti-Notch 2/3 Antibody Omp-59R5 in Combination with Etoposide and Cisplatin (Ep) in Patients (Pts) with Untreated Extensive-Stage Small-Cell Lung Cancer (Ed-Sclc): the Pinnacle Study. Annals Of Oncology 2014, 25: iv514. DOI: 10.1093/annonc/mdu355.11.Peer-Reviewed Original ResearchDose-limiting toxicityAnti-tumor activityDay 1Untreated extensive stage small cell lung cancerExtensive-stage small-cell lung cancerMain dose-limiting toxicitySmall cell lung cancerGrade 3 diarrheaGrade 3 nauseaPhase 2 partPhase 1b trialPK/pharmacodynamicsED-SCLCSCLC xenograftsDose cohortsRECIST 1.1Peripheral edemaUnacceptable toxicityAdverse eventsSupportive carePreliminary efficacyLung cancerDisease progressionEfficacy dataIgG2 antibodies