2004
The Abl-related gene (Arg) requires its F-actin–microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion
Miller AL, Wang Y, Mooseker MS, Koleske AJ. The Abl-related gene (Arg) requires its F-actin–microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion. Journal Of Cell Biology 2004, 165: 407-420. PMID: 15138293, PMCID: PMC2172189, DOI: 10.1083/jcb.200308055.Peer-Reviewed Original ResearchConceptsLamellipodial dynamicsCross-linking activityF-actin-binding domainFluorescent protein fusionsMT-binding domainNonreceptor tyrosine kinaseFilamentous actin bundlesWild-type fibroblastsCell polarityProtein fusionsMembrane protrusionsCell peripheryLamellipodial protrusionCell protrusionsActin bundlesMolecular mechanismsTyrosine kinaseF-actinMicrotubulesArgFibroblast adhesionABLHigh affinityFibroblastsProtrusion
1995
Caveolae and human disease: functional roles in transcytosis, potocytosis, signalling and cell polarity
Lisanti M, Scherer P, Tang Z, Kübler E, Koleske A, Sargiacomo M. Caveolae and human disease: functional roles in transcytosis, potocytosis, signalling and cell polarity. Seminars In Cell And Developmental Biology 1995, 6: 47-58. DOI: 10.1016/s1044-5781(06)80084-8.Peer-Reviewed Original ResearchHeterotrimeric G proteinsSrc-like kinasesTranscytosis of macromoleculesCertain transmembraneCell polarityRap GTPasesAnion transport proteinMembrane porinsBiochemical isolationPlasma membraneDiverse functionsTransport proteinsG proteinsCell transformationHuman diseasesMolecular componentsFunctional roleMembranous structuresCaveolaeEpithelial cellsMolecular pathogenesisScavenger receptorsSmall moleculesCapillary endothelial cellsGPI