2017
CNS Neurons Deposit Laminin α5 to Stabilize Synapses
Omar MH, Campbell M, Xiao X, Zhong Q, Brunken WJ, Miner JH, Greer CA, Koleske AJ. CNS Neurons Deposit Laminin α5 to Stabilize Synapses. Cell Reports 2017, 21: 1281-1292. PMID: 29091766, PMCID: PMC5776391, DOI: 10.1016/j.celrep.2017.10.028.Peer-Reviewed Original ResearchConceptsDendritic spine head sizeLaminin α5Larger postsynaptic densitiesDendritic spine densitySpine head sizeAge-dependent lossDendritic spine sizeEnhanced neurotransmissionSpine densityHippocampal neuronsDendritic spinesConditional deletionLaminin β2Postsynaptic densitySynapsesSpine sizeEarly adulthoodBehavioral defectsNeuronsBrainHead sizeMolecular mechanismsΑ5LamininNeurotransmission
2007
Defective T Cell Development and Function in the Absence of Abelson Kinases
Gu JJ, Zhang N, He YW, Koleske AJ, Pendergast AM. Defective T Cell Development and Function in the Absence of Abelson Kinases. The Journal Of Immunology 2007, 179: 7334-7343. PMID: 18025176, DOI: 10.4049/jimmunol.179.11.7334.Peer-Reviewed Original ResearchConceptsT cell developmentT cellsMutant miceCell-autonomous roleT cell-dependent AgCD8 T cellsListeria monocytogenes infectionT cell expansionCell developmentNumber of thymocytesT cell functionDouble-positive stageDouble-negative populationDefective T cell developmentConditional knockout miceT cells resultsNull T cellsTCR-induced signalingCytokine productionMonocytogenes infectionAb productionKnockout miceThymocyte proliferationConditional deletionMice