2015
A Detailed Evaluation of Transplant-Related Toxicities and Outcome for Patients with CNS Lymphoma (CNSL) Consolidated with High-Dose Therapy and Autologous Stem Cell Transplantation (HDT-ASCT) Using Thiotepa, Busulfan (Bu), Cyclophosphamide (TBC) Conditioning
Scordo M, Bhatt V, Hsu M, Omuro A, Matasar M, DeAngelis L, Dahi P, Moskowitz C, Giralt S, Sauter C. A Detailed Evaluation of Transplant-Related Toxicities and Outcome for Patients with CNS Lymphoma (CNSL) Consolidated with High-Dose Therapy and Autologous Stem Cell Transplantation (HDT-ASCT) Using Thiotepa, Busulfan (Bu), Cyclophosphamide (TBC) Conditioning. Blood 2015, 126: 4354. DOI: 10.1182/blood.v126.23.4354.4354.Peer-Reviewed Original ResearchNon-hematologic toxicitiesProgression-free survivalKaplan-Meier curvesSignificant grade 3HDT-ASCTMore grade 3Whole brain radiotherapyKarnofsky performance statusOverall survivalCNS lymphomaGrade 3Prior regimensHematopoietic cell transplant comorbidity indexAutologous stem cell transplantationHigh-dose therapyTransplant-related mortalityKaplan-Meier methodProspective clinical trialsRetrospective chart reviewStem cell transplantationGroups of ptsInitiation of conditioningYears of ageBU pharmacokineticsCTCAE 4.0
2014
AI-09PATTERNS OF SALVAGE TREATMENT FOR HIGH GRADE GLIOMA IN THE TEMOZOLOMIDE ERA
Escorcia F, Folkert M, Spratt D, Zumsteg Z, Chan T, Omuro A, Beal K, Gutin P, Yamada J. AI-09PATTERNS OF SALVAGE TREATMENT FOR HIGH GRADE GLIOMA IN THE TEMOZOLOMIDE ERA. Neuro-Oncology 2014, 16: v3-v3. PMCID: PMC4217875, DOI: 10.1093/neuonc/nou238.9.Peer-Reviewed Original ResearchHigh-grade gliomasSalvage radiation therapyTreatment-related factorsTrimodality therapyRadiation therapySalvage chemotherapyHazard ratioOverall survivalGrade gliomasOnly treatment-related factorOptimal salvage therapyKaplan-Meier methodCox regression modelingGrade IV patientsLarge retrospective seriesConfidence intervalsSalvage therapyTrimodality treatmentBilateral diseaseInitial surgeryRecurrent diseaseSalvage surgerySalvage treatmentIV patientsConsecutive patients