2022
Current Therapy for Metastatic Head and Neck Cancer: Evidence, Opportunities, and Challenges.
Wise-Draper TM, Bahig H, Tonneau M, Karivedu V, Burtness B. Current Therapy for Metastatic Head and Neck Cancer: Evidence, Opportunities, and Challenges. American Society Of Clinical Oncology Educational Book 2022, 42: 1-14. PMID: 35486888, DOI: 10.1200/edbk_350442.Peer-Reviewed Original ResearchConceptsNeck squamous cell carcinomaSquamous cell carcinomaMetastatic headCell carcinomaSystemic therapyFirst-line systemic therapyFirst-line immunotherapyInclusion of chemotherapyImmune checkpoint blockadeNew systemic therapiesNumber of patientsAggressive local managementCombination immunotherapyLocoregional therapyOligometastatic diseaseCheckpoint blockadeNovel immunotherapiesPD-L1Lung metastasesRetrospective studyBiomarker subgroupsCurrent therapiesNeck cancerAblative approachesAntiangiogenic agents
2010
Nonsurgical management of oropharyngeal, laryngeal, and hypopharyngeal cancer: The Fox Chase Cancer Center experience
Andrews G, Lango M, Cohen R, Feigenberg S, Burtness B, Mehra R, Ahmed S, Nicolaou N, Gaughan J, Ridge JA. Nonsurgical management of oropharyngeal, laryngeal, and hypopharyngeal cancer: The Fox Chase Cancer Center experience. Head & Neck 2010, 33: 1433-1440. PMID: 21928415, DOI: 10.1002/hed.21615.Peer-Reviewed Original ResearchMeSH KeywordsCancer Care FacilitiesCarcinoma, Squamous CellChemoradiotherapy, AdjuvantCohort StudiesDisease-Free SurvivalFemaleHumansHypopharyngeal NeoplasmsLaryngeal NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalOropharyngeal NeoplasmsProportional Hazards ModelsRadiotherapy, ConformalRadiotherapy, Intensity-ModulatedRetrospective StudiesSalvage TherapySmokingConceptsSurvival of patientsNumber of patientsOropharyngeal cancerHypopharyngeal cancerT classificationLaryngeal cancerFox Chase Cancer Center experienceRetrospective single-institution cohort studyMultivariate analysisSingle-institution cohort studyRecurrent oropharyngeal cancerCancer Center experienceRecurrence-free survivalSubset of patientsLaryngeal cancer patientsDisease-related deathEarly T classificationHypopharyngeal cancer treatmentChemotherapy useCurative intentLocoregional controlCohort studyCurrent smokersOverall survivalSalvage surgery