1998
Characterization of the ryanodine receptor/channel of invertebrate muscle
Quinn K, Castellani L, Ondrias K, Ehrlich B. Characterization of the ryanodine receptor/channel of invertebrate muscle. American Journal Of Physiology 1998, 274: r494-r502. PMID: 9486309, DOI: 10.1152/ajpregu.1998.274.2.r494.Peer-Reviewed Original ResearchConceptsInvertebrate musclesRyanodine receptor/channelVertebrate skeletal muscleDiverse organismsCalcium release channel/ryanodine receptorRelease channel/ryanodine receptorChannel/ryanodine receptorSingle-channel conductanceReceptor/channelElectron microscopic analysisRyanodine receptorSkeletal muscleRelease channelCytoplasmic Ca2Single-channel currentsSpecific ryanodine bindingChannel conductanceSarcoplasmic reticulumRyRsRuthenium redInvertebratesCa2MammalianRyanodine bindingOrganisms
1993
ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites
Bezprozvanny I, Ehrlich B. ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites. Neuron 1993, 10: 1175-1184. PMID: 7686381, DOI: 10.1016/0896-6273(93)90065-y.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsCalciumCalcium ChannelsCerebellumDogsEndoplasmic ReticulumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsIon Channel GatingIon ChannelsKineticsLipid BilayersMathematicsMicrosomesModels, NeurologicalReceptors, Cell SurfaceReceptors, Cytoplasmic and NuclearSignal TransductionConceptsPresence of IP3Effect of ATPTrisphosphate-gated channelsIntracellular Ca2Average durationAllosteric modulationSingle-channel levelFunction of inositolIP3 receptorChannel activityCell viabilityReceptorsTrisphosphate receptorIP3Channel openingPermeable channelsCa2ATPInositolAddition of ATPNonhydrolyzable ATP analogChannel conductanceChannel incorporation