2001
Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators
Thrower E, Hagar R, Ehrlich B. Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators. Trends In Pharmacological Sciences 2001, 22: 580-586. PMID: 11698102, DOI: 10.1016/s0165-6147(00)01809-5.Peer-Reviewed Original Research
1996
Ligand-gated calcium channels inside and out
Striggow F, Ehrlich B. Ligand-gated calcium channels inside and out. Current Opinion In Cell Biology 1996, 8: 490-495. PMID: 8791458, DOI: 10.1016/s0955-0674(96)80025-1.Peer-Reviewed Original ResearchConceptsLigand-gated calcium channelsStore-operated channelsCalcium-permeable channelsIntracellular membranesFunctional characterizationPlasma membraneAllosteric mechanismAssociated proteinsTrisphosphate receptorCalcium releaseRyanodine receptorIntracellular storesIntracellular calciumCalcium channelsMembraneReceptorsProteinTypes of channelsInositolRelease
1995
Functional properties of intracellular calcium-release channels
Ehrlich B. Functional properties of intracellular calcium-release channels. Current Opinion In Neurobiology 1995, 5: 304-309. PMID: 7580152, DOI: 10.1016/0959-4388(95)80042-5.Peer-Reviewed Original ResearchConceptsIntracellular calcium release channelsCalcium release channelLarge ion channelsCellular rolesCytoplasmic proteinsMolecular mechanismsRegulatory sitesTrisphosphate receptorFunctional interactionIon channelsRegulatory processesMajor classesRyanodine receptorProteinRecent studiesFunctional propertiesReceptorsCytoplasmInositol
1993
ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites
Bezprozvanny I, Ehrlich B. ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites. Neuron 1993, 10: 1175-1184. PMID: 7686381, DOI: 10.1016/0896-6273(93)90065-y.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsCalciumCalcium ChannelsCerebellumDogsEndoplasmic ReticulumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsIon Channel GatingIon ChannelsKineticsLipid BilayersMathematicsMicrosomesModels, NeurologicalReceptors, Cell SurfaceReceptors, Cytoplasmic and NuclearSignal TransductionConceptsPresence of IP3Effect of ATPTrisphosphate-gated channelsIntracellular Ca2Average durationAllosteric modulationSingle-channel levelFunction of inositolIP3 receptorChannel activityCell viabilityReceptorsTrisphosphate receptorIP3Channel openingPermeable channelsCa2ATPInositolAddition of ATPNonhydrolyzable ATP analogChannel conductanceChannel incorporation