1998
Characterization of the ryanodine receptor/channel of invertebrate muscle
Quinn K, Castellani L, Ondrias K, Ehrlich B. Characterization of the ryanodine receptor/channel of invertebrate muscle. American Journal Of Physiology 1998, 274: r494-r502. PMID: 9486309, DOI: 10.1152/ajpregu.1998.274.2.r494.Peer-Reviewed Original ResearchConceptsInvertebrate musclesRyanodine receptor/channelVertebrate skeletal muscleDiverse organismsCalcium release channel/ryanodine receptorRelease channel/ryanodine receptorChannel/ryanodine receptorSingle-channel conductanceReceptor/channelElectron microscopic analysisRyanodine receptorSkeletal muscleRelease channelCytoplasmic Ca2Single-channel currentsSpecific ryanodine bindingChannel conductanceSarcoplasmic reticulumRyRsRuthenium redInvertebratesCa2MammalianRyanodine bindingOrganisms
1994
The pharmacology of intracellular Ca2+-release channels
Ehrlich B, Kaftan E, Bezprozvannaya S, Bezprozvanny I. The pharmacology of intracellular Ca2+-release channels. Trends In Pharmacological Sciences 1994, 15: 145-149. PMID: 7754532, DOI: 10.1016/0165-6147(94)90074-4.Peer-Reviewed Original ResearchStabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein
Brillantes A, Ondrias K, Scott A, Kobrinsky E, Ondriašová E, Moschella M, Jayaraman T, Landers M, Ehrlich B, Marks A. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein. Cell 1994, 77: 513-523. PMID: 7514503, DOI: 10.1016/0092-8674(94)90214-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCaffeineCalciumCalcium ChannelsCarrier ProteinsCell LineCloning, MolecularGene ExpressionHeat-Shock ProteinsIon Channel GatingIsometric ContractionLipid BilayersMuscle ProteinsPolyenesRabbitsRatsRecombinant ProteinsRNA, MessengerRuthenium RedRyanodineRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumSirolimusTacrolimusTacrolimus Binding ProteinsConceptsCellular functionsFK506-binding proteinNatural cellular functionsRelease channel functionInsect cellsProline isomeraseIsomerase activityEndoplasmic reticulumChannel functionFKBP12Channel complexRyanodine receptorCytosolic receptorRelease channel complexRelease channelRapamycinProteinFunctional Ca2Open probabilityCaffeine activationIntracellular Ca2Mean open timeImmunosuppressant drugsCopurifiesReceptors
1991
Comparison of calcium release from sarcoplasmic reticulum of slow and fast twitch muscles
Lee Y, Ondrias K, Duhl A, Ehrlich B, Kim D. Comparison of calcium release from sarcoplasmic reticulum of slow and fast twitch muscles. The Journal Of Membrane Biology 1991, 122: 155-163. PMID: 1716686, DOI: 10.1007/bf01872638.Peer-Reviewed Original ResearchConceptsFast sarcoplasmic reticulumFast-twitch muscleSarcoplasmic reticulumRelease channelSlow sarcoplasmic reticulumTwitch muscleFast musclesSR vesiclesTypes of muscleCalcium releaseMechanism of Ca2MuscleScatchard analysisRyanodine receptorFunctional assaysRuthenium redSingle Ca2Single-channel conductanceOpen probabilityMolecular weight proteinsCa2Closed timeHigh molecular weight proteinsFunctional differences