2020
Prognostic Significance of Extranodal Extension in HPV‐Mediated Oropharyngeal Carcinoma: A Systematic Review and Meta‐analysis
Benchetrit L, Torabi SJ, Givi B, Haughey B, Judson BL. Prognostic Significance of Extranodal Extension in HPV‐Mediated Oropharyngeal Carcinoma: A Systematic Review and Meta‐analysis. Otolaryngology 2020, 164: 720-732. PMID: 32838649, DOI: 10.1177/0194599820951176.Peer-Reviewed Original ResearchConceptsOropharyngeal squamous cell carcinomaExtranodal extensionHazard ratioSystematic reviewHuman papilloma virus-positive oropharyngeal squamous cell carcinomaPathologic extranodal extensionDisease-specific survivalCohort of patientsRefined risk stratificationSquamous cell carcinomaRadiologic extranodal extensionRandom-effects modelDeintensification trialsCause mortalityDistant recurrenceLocoregional recurrenceOverall survivalOropharyngeal carcinomaPrognostic roleDistant metastasisRisk stratificationPrognostic significanceCell carcinomaPrognostic outcomesObservational study
2018
Survival Outcomes for Induction vs Adjuvant Chemotherapy in Squamous Cell Carcinoma of the Maxillary Sinus
Kuo P, Torabi SJ, Kraus D, Judson BL. Survival Outcomes for Induction vs Adjuvant Chemotherapy in Squamous Cell Carcinoma of the Maxillary Sinus. Otolaryngology 2018, 160: 658-663. PMID: 30296902, DOI: 10.1177/0194599818804777.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseAdjuvant chemotherapyMultivariate Cox regressionInduction chemotherapyLog-rank testMaxillary sinus cancerOverall survivalCox regressionSinus cancerMaxillary sinusUnivariate Kaplan-Meier analysisPoor local control ratesAdvanced maxillary sinus cancerAdjuvant chemotherapy cohortImproved overall survivalLocal control rateMortality hazard ratioKaplan-Meier analysisSquamous cell carcinomaSignificant mortality hazard ratiosSecondary database analysisWarrants further investigationPropensity-score matchingChemotherapy cohortHazard ratio
2016
Proposing prognostic thresholds for lymph node yield in clinically lymph node‐negative and lymph node‐positive cancers of the oral cavity
Kuo P, Mehra S, Sosa JA, Roman SA, Husain ZA, Burtness BA, Tate JP, Yarbrough WG, Judson BL. Proposing prognostic thresholds for lymph node yield in clinically lymph node‐negative and lymph node‐positive cancers of the oral cavity. Cancer 2016, 122: 3624-3631. PMID: 27479645, DOI: 10.1002/cncr.30227.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseOral cavity cancerMortality hazard ratioLymph nodesHazard ratioNeck dissectionLymph node-negative cancersLymph node-positive cancersNode-positive cancersNode-positive cohortPositive lymph nodesTherapeutic neck dissectionEnd Results (SEER) databaseLymph node yieldHigh-volume centersExtensive neck dissectionMultiple cancer sitesNode-negative cancersOverall survivalHigher lymphPrognostic factorsTreatment guidelinesNode yieldResults databaseSurgical management