2023
Prognostic value of absolute lymphocyte count in oral cavity squamous cell carcinoma
Shah R, Liu C, Shah H, Judson B. Prognostic value of absolute lymphocyte count in oral cavity squamous cell carcinoma. Laryngoscope Investigative Otolaryngology 2023, 8: 870-875. PMID: 37621277, PMCID: PMC10446262, DOI: 10.1002/lio2.1094.Peer-Reviewed Original ResearchOral cavity squamous cell carcinomaAbsolute lymphocyte countOral cavity cancerSquamous cell carcinomaRate of deathLikelihood of recurrenceLymphocyte countPrognostic valueCell carcinomaCancer patientsPreoperative absolute lymphocyte countPretreatment absolute lymphocyte countLate-stage cancer patientsRetrospective chart reviewAmerican Joint CommitteeDay of surgeryEarly-stage cancer patientsTumor registry dataAdjuvant therapyOutcome patientsChart reviewPrimary outcomeALC valuesPositive marginsPrognostic indicator
2021
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma
Lechner M, Takahashi Y, Turri-Zanoni M, Liu J, Counsell N, Hermsen M, Kaur RP, Zhao T, Ramanathan M, Schartinger VH, Emanuel O, Helman S, Varghese J, Dudas J, Riechelmann H, Sprung S, Haybaeck J, Howard D, Engel NW, Stewart S, Brooks L, Pickles JC, Jacques TS, Fenton TR, Williams L, Vaz FM, O'Flynn P, Stimpson P, Wang S, Hannan SA, Unadkat S, Hughes J, Dwivedi R, Forde CT, Randhawa P, Gane S, Joseph J, Andrews PJ, Royle G, Franchi A, Maragliano R, Battocchio S, Bewicke-Copley H, Pipinikas C, Webster A, Thirlwell C, Ho D, Teschendorff A, Zhu T, Steele CD, Pillay N, Vanhaesebroeck B, Mohyeldin A, Fernandez-Miranda J, Park KW, Le QT, West RB, Saade R, Manes RP, Omay SB, Vining EM, Judson BL, Yarbrough WG, Sansovini M, Silvia N, Grassi I, Bongiovanni A, Capper D, Schüller U, Thavaraj S, Sandison A, Surda P, Hopkins C, Ferrari M, Mattavelli D, Rampinelli V, Facchetti F, Nicolai P, Bossi P, Henriquez OA, Magliocca K, Solares CA, Wise SK, Llorente JL, Patel ZM, Nayak JV, Hwang PH, Lacy PD, Woods R, O'Neill JP, Jay A, Carnell D, Forster MD, Ishii M, London NR, Bell DM, Gallia GL, Castelnuovo P, Severi S, Lund VJ, Hanna EY. Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma. European Journal Of Cancer 2021, 162: 221-236. PMID: 34980502, PMCID: PMC9554673, DOI: 10.1016/j.ejca.2021.09.046.Peer-Reviewed Original ResearchConceptsPeptide radionuclide receptor therapyProphylactic neck irradiationDisease-free survivalOlfactory neuroblastomaSomatostatin receptor 2Stable diseaseAdjuvant radiotherapyNeck irradiationOverall survivalReceptor 2Potential efficacyPeptide receptor radionuclide therapyReceptor radionuclide therapyMultivariable survival analysisPertinent clinical dataClinical trial dataKey prognostic markersNodal recurrenceClinical outcomesClinicopathological characteristicsT stagePrognostic valueReceptor therapyDisease stageNeuroblastoma patients
2018
Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands
Cheraghlou S, Yu PK, Otremba MD, Mehra S, Yarbrough WG, Judson BL. Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands. Cancers Of The Head & Neck 2018, 3: 5. PMID: 31093358, PMCID: PMC6460801, DOI: 10.1186/s41199-018-0032-x.Peer-Reviewed Original ResearchSignificant prognostic indicatorPrognostic indicatorMajor salivary glandsAdverse featuresSalivary cancerPrognostic valueECE statusUnivariate Kaplan-Meier analysisAdditional adverse featuresCox survival regressionNode-positive cancersNon-squamous cancersPost-operative radiotherapyHigh-risk featuresSalivary glandsPositive surgical marginsKaplan-Meier analysisSquamous cell cancerSalivary gland cancerSCC patientsMucosal headWorse survivalImproved survivalSurgical marginsCell cancerPrognostic Value of Lymph Node Yield and Density in Head and Neck Malignancies
Cheraghlou S, Otremba M, Yu P, Agogo GO, Hersey D, Judson BL. Prognostic Value of Lymph Node Yield and Density in Head and Neck Malignancies. Otolaryngology 2018, 158: 1016-1023. PMID: 29460685, DOI: 10.1177/0194599818756830.Peer-Reviewed Original ResearchConceptsLymph node densityLymph node yieldNeck dissectionNode yieldNeck malignanciesLaird random-effects modelElective neck dissectionEnglish language original researchOvid/EmbaseOvid/MedlineHeterogeneity of studiesRandom-effects modelAdjuvant therapyNodal yieldNonduplicate articlesPrognostic significancePrognostic valuePatient counselingNeck cancerPooled resultsPatient outcomesPoor survivalPubMed databaseSurvival analysisDissection
2012
Role of excision repair cross‐complementation 1 expression as a prognostic marker for response to radiotherapy in early‐stage laryngeal cancer
Johung K, Rewari A, Wu H, Judson B, Contessa JN, Haffty BG, Decker RH. Role of excision repair cross‐complementation 1 expression as a prognostic marker for response to radiotherapy in early‐stage laryngeal cancer. Head & Neck 2012, 35: 852-857. PMID: 22740347, PMCID: PMC5723082, DOI: 10.1002/hed.23041.Peer-Reviewed Original ResearchConceptsERCC1 expressionOverall survivalExcision repair crossLocal controlT classificationLaryngeal cancerEarly-stage laryngeal cancerLaryngeal squamous cell carcinomaClinicopathologic risk factorsHigh ERCC1 expressionPlatinum-based chemotherapySquamous cell carcinomaWorse survivalCell carcinomaPrognostic valueStandard radiotherapyPrognostic markerRisk factorsEffective treatmentImmunohistochemical analysisTissue microarrayStage IRadiotherapy resistanceMultivariate analysisRadiotherapy