2020
Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review
Safi AF, Kauke M, Nelms L, Palmer WJ, Tchiloemba B, Kollar B, Haug V, Pomahač B. Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 74: 327-335. PMID: 33229219, DOI: 10.1016/j.bjps.2020.10.003.Peer-Reviewed Original ResearchConceptsLocal immunosuppressionSystematic reviewAllograft survivalComposite allotransplantationAllograft survival dataCell-based therapy strategiesImproved allograft survivalMain immunosuppressive agentMeta-Analyses (PRISMA) guidelinesPreclinical animal studiesPreferred Reporting ItemsMalignant side effectsImmunosuppressive agentsPreclinical dataSignificant prolongationRat modelHuman trialsExclusion criteriaImmunosuppressionSide effectsAnimal studiesReporting ItemsPubMed databaseSystemic toxicityTherapy strategies
2018
Kidney Dysfunction After Vascularized Composite Allotransplantation
Krezdorn N, Tasigiorgos S, Wo L, Lopdrup R, Turk M, Kiwanuka H, Ahmed S, Petruzzo P, Bueno E, Pomahac B, Riella L. Kidney Dysfunction After Vascularized Composite Allotransplantation. Transplantation Direct 2018, 4: e362. PMID: 30046652, PMCID: PMC6056276, DOI: 10.1097/txd.0000000000000795.Peer-Reviewed Original ResearchGlomerular filtration rateKidney dysfunctionCreatinine levelsTrough levelsRisk factorsCalcineurin inhibitor trough levelsNonrenal solid organ transplantsLong-term patient outcomesFirst year posttransplantSuccessful midterm outcomesRenal risk factorsSolid organ transplantsAlternative immunosuppressive agentsComposite tissue transplantationAcute rejectionVCA patientsYear posttransplantMidterm outcomesRenal dysfunctionIR patientsKidney complicationsRenal functionMajor complicationsImmunosuppressive agentsKidney parameters