Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review
Safi AF, Kauke M, Nelms L, Palmer WJ, Tchiloemba B, Kollar B, Haug V, Pomahač B. Local immunosuppression in vascularized composite allotransplantation (VCA): A systematic review. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 74: 327-335. PMID: 33229219, DOI: 10.1016/j.bjps.2020.10.003.Peer-Reviewed Original ResearchConceptsLocal immunosuppressionSystematic reviewAllograft survivalComposite allotransplantationAllograft survival dataCell-based therapy strategiesImproved allograft survivalMain immunosuppressive agentMeta-Analyses (PRISMA) guidelinesPreclinical animal studiesPreferred Reporting ItemsMalignant side effectsImmunosuppressive agentsPreclinical dataSignificant prolongationRat modelHuman trialsExclusion criteriaImmunosuppressionSide effectsAnimal studiesReporting ItemsPubMed databaseSystemic toxicityTherapy strategiesUse of venous couplers in microsurgical lower extremity reconstruction: A systematic review and meta‐analysis
Haug V, Panayi A, Kadakia N, Abdulrazzak O, Endo Y, Udeh K, Kollar B, Hundeshagen G, Pomahac B, Kneser U, Hirche C. Use of venous couplers in microsurgical lower extremity reconstruction: A systematic review and meta‐analysis. Microsurgery 2020, 41: 50-60. PMID: 32227603, DOI: 10.1002/micr.30581.Peer-Reviewed Original ResearchConceptsLower limb reconstructionHand-sewn anastomosisSystematic reviewLimb reconstructionVenous couplerMicrosurgical lower extremity reconstructionMore surgical complicationsAdditional prospective studiesMeta-Analyses (PRISMA) guidelinesLower extremity reconstructionFree tissue transferFull-text reviewQuality of reportingWeb of ScienceMicrovascular complicationsSurgical complicationsArterial compromiseCochrane CollaborationProspective studyCase reportVenous anastomosisClinical trialsLower extremitiesSurgical techniqueInclusion criteriaAll hands on deck: Hand replantation versus transplantation
Heineman J, Bueno E, Kiwanuka H, Carty M, Sampson C, Pribaz J, Pomahac B, Talbot S. All hands on deck: Hand replantation versus transplantation. SAGE Open Medicine 2020, 8: 2050312120926351. PMID: 32537157, PMCID: PMC7268554, DOI: 10.1177/2050312120926351.Peer-Reviewed Original ResearchHand replantationAdverse events/side effectsSystematic reviewPatient satisfaction/qualityPost-operative considerationsDeterminants of outcomePre-operative considerationsMeta-Analyses (PRISMA) guidelinesSatisfaction/qualityPreferred Reporting ItemsBest possible outcomeUpper limb lossAcute amputationsSurgical repairHand transplantationSurgical techniqueOperative techniquePatient commitmentComplete amputationDaily livingForearm levelLimb lossPatient expectationsSide effectsBetter outcomes