2022
T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation
Borges T, Abarzua P, Gassen R, Kollar B, Lima-Filho M, Aoyama B, Gluhova D, Clark R, Islam S, Pomahac B, Murphy G, Lian C, Talbot S, Riella L. T cell-attracting CCL18 chemokine is a dominant rejection signal during limb transplantation. Cell Reports Medicine 2022, 3: 100559. PMID: 35492875, PMCID: PMC9040185, DOI: 10.1016/j.xcrm.2022.100559.Peer-Reviewed Original ResearchConceptsLimb transplantationTransplant recipientsSkin antigen-presenting cellsSolid organ transplant recipientsAccelerated graft rejectionOrgan transplant recipientsSkin transplantation modelAntigen-presenting cellsLife-changing procedureImmunosuppressive approachesTh17 cellsGraft rejectionGreater immunogenicityCell infiltrationSkin biopsiesTransplantation modelSkin xenograftsChemokine CCL18Immune moleculesTransplantationCCL18RecipientsMolecular characterizationChemokinesCCR8 receptor
2008
Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery
Pomahac B, Aflaki P, Chandraker A, Pribaz J. Facial Transplantation and Immunosuppressed Patients: A New Frontier in Reconstructive Surgery. Transplantation 2008, 85: 1693-1697. PMID: 18580458, DOI: 10.1097/tp.0b013e318176b29e.Peer-Reviewed Original ResearchConceptsPartial face transplantationOrgan transplant recipientsFace transplantationTransplant recipientsLife-long immunosuppressionPatient selection criteriaRisk of malignancyComposite tissue transplantationFacial transplantationAlternative reconstructive methodImmunosuppressive regimenImmunosuppressive therapyAdditional immunosuppressionSurgical resectionImmunosuppressed patientsOrgan recipientsPatient populationWomen's HospitalReconstructive surgeryTransplantationIRB approvalSkin cancerReconstructive methodsControversial procedureTissue transplantation