2023
Vascularized Composite Allograft Versus Prosthetic for Reconstruction After Facial and Hand Trauma
Noel O, Dumbrava M, Daoud D, Kammien A, Kauke-Navarro M, Pomahac B, Colen D. Vascularized Composite Allograft Versus Prosthetic for Reconstruction After Facial and Hand Trauma. Annals Of Plastic Surgery 2023, 92: 100-105. PMID: 37962243, DOI: 10.1097/sap.0000000000003731.Peer-Reviewed Original ResearchConceptsHand traumaHand/upper extremityLong-term outcomesUpper extremity traumaDifferent reconstructive optionsUse of prosthesesExtremity traumaBenefit profileUpper extremityReconstructive optionsComposite allotransplantationFace traumaHand reconstructionTraumaClinical realityPrimary optionProsthesisPatientsVCA
2018
Software‐based video analysis of functional outcomes of face transplantation
Fischer S, Diehm Y, Dorante M, Kotsougiani D, Kueckelhaus M, Alhefzi M, Bueno E, Pomahac B. Software‐based video analysis of functional outcomes of face transplantation. Microsurgery 2018, 39: 53-61. PMID: 30159931, DOI: 10.1002/micr.30360.Peer-Reviewed Original ResearchConceptsFace transplantationNormal populationAssessment of outcomesDifferent time pointsFunctional outcomeFacial movementsPatient's abilitySame patientTransplantationMouth openingOutcome assessmentPatientsValuable assessment toolOpen mouthEye closureTime pointsRetrospective assessmentMonthsLip purseFacial transplantationAssessment toolSound evidenceOutcomesNoseEyebrowsFacial restoration by transplantation
Kollar B, Pomahac B. Facial restoration by transplantation. The Surgeon 2018, 16: 245-249. PMID: 29490887, DOI: 10.1016/j.surge.2018.01.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultFacial InjuriesFacial TransplantationFemaleHumansMaleMiddle AgedPlastic Surgery ProceduresConceptsWorld War I.World War IIModern plastic surgerySir Harold GilliesPeter Bent Brigham HospitalWar IIFace transplantationFirst successful kidney transplantationJoseph MurraySuccessful kidney transplantationNobel PrizeWorldFacial restorationKidney transplantationTransplant cohortUnique patientsWomen's HospitalSkin graftsOrgan transplantationTransplantationHospitalPlastic surgeonsPlastic surgerySoldiersBattlefield
2017
Role of Facial Vascularized Composite Allotransplantation in Burn Patients
Bharadia D, Sinha I, Pomahac B. Role of Facial Vascularized Composite Allotransplantation in Burn Patients. Clinics In Plastic Surgery 2017, 44: 857-864. PMID: 28888310, DOI: 10.1016/j.cps.2017.05.017.Peer-Reviewed Original ResearchMeSH KeywordsBurnsComposite Tissue AllograftsEstheticsFacial InjuriesFacial TransplantationHumansImmunosuppressive AgentsPatient SelectionConceptsComposite allotransplantationFacial Vascularized Composite AllotransplantationExtensive burn injuriesRisk of rejectionVascularized Composite AllotransplantationQuality of lifeLifelong regimenVCA patientsImmunosuppression medicationsPowerful reconstructive toolsBurn patientsTreatment optionsSurgical techniqueBurn injuryReconstructive surgeryPatientsReconstructive toolFace transplantationAllotransplantationImproved qualityFacial formImmunosuppressionMedicationsRegimenSurgeryFirst Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery
Fischer S, Lee T, Krezdorn N, Alhefzi M, Kueckelhaus M, Bueno E, Pomahac B. First Lower Two-Thirds Osteomyocutaneous Facial Allograft Perfused by a Unilateral Facial Artery. Plastic & Reconstructive Surgery 2017, 139: 1175e-1183e. PMID: 28445377, DOI: 10.1097/prs.0000000000003288.Peer-Reviewed Original ResearchConceptsFacial arteryFacial allograftImmunosuppressive therapyRejection episodesAirway volumeVenous outflowCLINICAL QUESTION/LEVELDual immunosuppressive therapyFacial allotransplantationTwo-thirdsMaintenance therapyMycophenolate mofetilSteroid pulseArtery anastomosisSurgical durationFacial functionTracheostomy tubeContralateral sideVascular anastomosisSubmental arteryTransplantationArteryAllograftsVascularization patternFacial formReflections on a Decade of Face Transplantation
Giatsidis G, Sinha I, Pomahac B. Reflections on a Decade of Face Transplantation. Annals Of Surgery 2017, 265: 841-846. PMID: 28032849, DOI: 10.1097/sla.0000000000001760.Peer-Reviewed Original ResearchConceptsFace transplantationSci-fi novelsEthical discussionPersonal strugglesSocial beliefsFace transplantSocietal implicationsMedical discoveriesMedical innovationScienceFace restorationPublic opinionHigh-risk trajectoriesTodayLong wayMedical communityRegulatory frameworkBeliefsStruggleSocietyReflectionAnswersQuestionsDiscussionAnniversary
2016
A Retrospective Analysis of Secondary Revisions after Face Transplantation
Aycart M, Alhefzi M, Kueckelhaus M, Krezdorn N, Bueno E, Caterson E, Pribaz J, Pomahac B. A Retrospective Analysis of Secondary Revisions after Face Transplantation. Plastic & Reconstructive Surgery 2016, 138: 690e-701e. PMID: 27673540, DOI: 10.1097/prs.0000000000002605.Peer-Reviewed Original ResearchConceptsFree tissue transferSecondary revisionFace transplantationMedical recordsRetrospective analysisTissue transferCLINICAL QUESTION/LEVELA Retrospective AnalysisDevastating facial injuriesSkin flap lossMedian time intervalAutologous free tissue transferPatients' medical recordsLocal tissue rearrangementAcute rejectionMaintenance immunosuppressionPulse steroidsPostoperative complicationsMajor infectionSuperficial musculoaponeurotic system plicationCertain patientsOperative reportsRevision surgeryFlap lossRevision proceduresThe role of face transplantation in the self-inflicted gunshot wound
Kiwanuka H, Aycart M, Gitlin D, Devine E, Perry B, Win T, Bueno E, Alhefzi M, Krezdorn N, Pomahac B. The role of face transplantation in the self-inflicted gunshot wound. Journal Of Plastic Reconstructive & Aesthetic Surgery 2016, 69: 1636-1647. PMID: 27720683, DOI: 10.1016/j.bjps.2016.08.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultBone TransplantationDecision Making, Computer-AssistedFacial InjuriesFacial TransplantationFemaleHumansMaleMass ScreeningMiddle AgedPatient SatisfactionPlastic Surgery ProceduresPsychological TechniquesRetrospective StudiesSelf-Injurious BehaviorSurgical FlapsTreatment OutcomeUnited StatesWounds, GunshotConceptsSelf-inflicted gunshot woundsFace transplantationGunshot woundsFT recipientsPsychosocial outcomesSubset of patientsPartial face transplantationFree tissue transferLoco-regional flapsSerial debridementConventional reconstructionWomen's HospitalMultidisciplinary evaluationRetrospective analysisAesthetic deficitsNormal restorationSoft tissue repairMental illnessTissue transferReconstructive surgeonPsychosocial componentsSuicidal behaviorScreening processMidfacial defectsRecipientsPatient Recruitment and Referral Patterns in Face Transplantation
Kiwanuka H, Aycart M, Bueno E, Alhefzi M, Krezdorn N, Pomahac B. Patient Recruitment and Referral Patterns in Face Transplantation. Plastic & Reconstructive Surgery 2016, 138: 224-231. PMID: 27348655, DOI: 10.1097/prs.0000000000002268.Peer-Reviewed Original ResearchConceptsReferral patternsPhysician referralPatient recruitmentFace transplantationDemographic characteristicsShort-term resultsClinical trial statusPatient characteristicsTransplantation centersRetrospective reviewAuthors' centerClinical trialsImmediate exclusionAesthetic deficitsPhysician educationAverage ageBurn communityTrial statusProtocol approvalRelationship of characteristicsTransplantationReferralUnited StatesAreas of improvementInjury
2015
Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation
Kueckelhaus M, Turk M, Kumamaru K, Wo L, Bueno E, Lian C, Alhefzi M, Aycart M, Fischer S, De Girolami U, Murphy G, Rybicki F, Pomahac B. Transformation of Face Transplants: Volumetric and Morphologic Graft Changes Resemble Aging After Facial Allotransplantation. American Journal Of Transplantation 2015, 16: 968-978. PMID: 26639618, DOI: 10.1111/ajt.13544.Peer-Reviewed Original ResearchConceptsLong-term outcomesFacial allograftFacial allotransplantationSuperior long-term outcomesShort-term resultsRisk-benefit assessmentSoft tissue volumeSignificant volume lossTransplant recipientsVolume lossDiagnostic evaluationDonor selectionMuscle biopsyHistological evaluationComputed tomographyBone atrophyAllograftsFuture clinical routineNormal anatomyRecipient tissuesAllotransplantationClinical routineMorphometric changesSoft tissueMuscle fibersFacial transplantation
Wo L, Bueno E, Pomahac B. Facial transplantation. Current Opinion In Organ Transplantation 2015, Publish Ahead of Print: &na;. PMID: 26536422, DOI: 10.1097/mot.0000000000000253.Peer-Reviewed Original ResearchMeSH KeywordsAllograftsFacial InjuriesFacial TransplantationHumansRisk FactorsUpper ExtremityVascularized Composite AllotransplantationConceptsPositive HIV statusHIV statusFace transplantComposite allotransplantationUpper extremity transplantsDonor-specific antigensHistory of malignancyLatent viral infectionFacial transplantationChronic rejectionSimultaneous transplantationAbsolute contraindicationCase reportCurrent guidelinesFacial injuriesViral infectionTransplantTransplantationMedical teamAllotransplantationFirst face transplantFace transplantationFacial allotransplantationPatientsPsychological healthReconstructive Management of Devastating Electrical Injuries to the Face
Janis J, Khansa I, Lehrman C, Orgill D, Pomahac B. Reconstructive Management of Devastating Electrical Injuries to the Face. Plastic & Reconstructive Surgery 2015, 136: 839-847. PMID: 26090762, DOI: 10.1097/prs.0000000000001619.Peer-Reviewed Original ResearchConceptsElectrical injuryFace transplantationCase seriesTrauma centerReconstructive challengeLevel 1 trauma centerCLINICAL QUESTION/LEVELRetrospective case seriesLarge case seriesCare of patientsLife-threatening injuriesComposite tissue allotransplantationSignificant reconstructive challengePotential recipient vesselsReconstructive managementRenal impairmentAntigen sensitizationInitial managementElectrical burnsReconstructive proceduresMicrosurgical reconstructionPatient injuryRecipient vesselsCardiac arrhythmiasTissue allotransplantationFacial Restoration by Transplantation
Westvik T, Dermietzel A, Pomahac B. Facial Restoration by Transplantation. Annals Of Plastic Surgery 2015, 74: s2-s8. PMID: 25875907, DOI: 10.1097/sap.0000000000000525.Peer-Reviewed Original ResearchManagement of Steroid-resistant Late Acute Cellular Rejection Following Face Transplantation: A Case Report
Janis J, MacKenzie K, Wright S, Pomahac B, Lu C, Susa J, Wada S, Vazquez M, Chong T, Tullius S. Management of Steroid-resistant Late Acute Cellular Rejection Following Face Transplantation: A Case Report. Transplantation Proceedings 2015, 47: 223-225. PMID: 25645808, DOI: 10.1016/j.transproceed.2014.09.152.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntilymphocyte SerumBurnsFacial InjuriesFacial TransplantationGraft RejectionHumansImmunosuppressive AgentsMale
2014
Airway Recovery after Face Transplantation
Fischer S, Wallins J, Bueno E, Kueckelhaus M, Chandawarkar A, Diaz-Siso J, Larson A, Murphy G, Annino D, Caterson E, Pomahac B. Airway Recovery after Face Transplantation. Plastic & Reconstructive Surgery 2014, 134: 946e-954e. PMID: 25415117, DOI: 10.1097/prs.0000000000000752.Peer-Reviewed Original ResearchMeSH KeywordsAirway ObstructionFacial InjuriesFacial TransplantationHumansMaleNasal MucosaTomography, X-Ray ComputedTreatment OutcomeConceptsAirway volumeUpper airwayFace transplantationRespiratory mucosaNasal passagesIncidence of sinusitisUpper airway infectionsUpper airway impairmentSevere facial injuriesQuality of lifeLife-altering consequencesAirway recoveryTracheostomy decannulationChronic coughAirway infectionFunctional airwayAirway impairmentNasal breathingTracheostomy tubeNasal mucosaSurgical correctionTomographic scanWomen's HospitalMucin productionFacial injuriesFunctional Outcomes of Face Transplantation
Fischer S, Kueckelhaus M, Pauzenberger R, Bueno E, Pomahac B. Functional Outcomes of Face Transplantation. American Journal Of Transplantation 2014, 15: 220-233. PMID: 25359281, DOI: 10.1111/ajt.12956.Peer-Reviewed Original ResearchEarly Postoperative Imaging and Image-Guided Procedures on Patients with Face Transplants
Lee T, Chansakul T, Huang R, Wrubel G, Mukundan S, Annino D, Pribaz J, Pomahac B. Early Postoperative Imaging and Image-Guided Procedures on Patients with Face Transplants. American Journal Of Neuroradiology 2014, 36: 568-574. PMID: 25339651, PMCID: PMC8013040, DOI: 10.3174/ajnr.a4141.Peer-Reviewed Original ResearchConceptsPostoperative imagingImage-guided proceduresFace transplantationFluid collectionCommon postoperative findingEarly postoperative imagingLymph node biopsyManagement of complicationsPostoperative fluid collectionsNode biopsyPostoperative findingsFacial edemaConsecutive casesWomen's HospitalInvasive proceduresRetrospective evaluationTransplantationFace transplantComplicationsHospitalImagingLymphadenopathyEdemaPatientsBiopsy
2013
Lessons Learned from Simultaneous Face and Bilateral Hand Allotransplantation
Carty M, Hivelin M, Dumontier C, Talbot S, Benjoar M, Pribaz J, Lantieri L, Pomahac B. Lessons Learned from Simultaneous Face and Bilateral Hand Allotransplantation. Plastic & Reconstructive Surgery 2013, 132: 423-432. PMID: 23584623, DOI: 10.1097/prs.0b013e318295883d.Peer-Reviewed Original ResearchFacial allotransplantation: A 3-year follow-up report
Diaz-Siso J, Parker M, Bueno E, Sisk G, Pribaz J, Eriksson E, Annino D, Tullius S, Pomahac B. Facial allotransplantation: A 3-year follow-up report. Journal Of Plastic Reconstructive & Aesthetic Surgery 2013, 66: 1458-1463. PMID: 23911716, DOI: 10.1016/j.bjps.2013.06.046.Peer-Reviewed Original ResearchConceptsQuality of lifeFunctional recoveryFace transplantationFirst postoperative yearPatients' functional recoveryPost-operative monthHigh-voltage burnsSatisfactory aesthetic resultsFace transplant patientsSevere facial defectsImmunosuppression dosesSteroid therapyPostoperative yearTransplant patientsMale patientsNormal sensationImmunologic complicationsWomen's HospitalMotor functionSurgical techniquePatient reportsReconstructive surgeryClose monitoringMultidisciplinary teamOccupational therapy
2012
A Position Paper in Support of Face Transplantation in the Blind
Carty M, Bueno E, Lehmann L, Pomahac B. A Position Paper in Support of Face Transplantation in the Blind. Plastic & Reconstructive Surgery 2012, 130: 319-324. PMID: 22495209, DOI: 10.1097/prs.0b013e3182589b27.Peer-Reviewed Original Research