1994
Platelet alpha-granule release in cocaine users.
Rinder HM, Ault KA, Jatlow PI, Kosten TR, Smith BR. Platelet alpha-granule release in cocaine users. Circulation 1994, 90: 1162-1167. PMID: 7522132, DOI: 10.1161/01.cir.90.3.1162.Peer-Reviewed Original ResearchConceptsAlpha-granule releasePlatelet alpha-granule releaseCocaine useCocaine usersBaseline levelsHigher mean baseline levelsLong-term cocaine usePeak plasma cocaine levelsPlatelet P-selectin expressionMean baseline levelPlasma cocaine levelsP-selectin expressionPlatelet-rich thrombiPlacebo infusionFlow cytometric methodArterial occlusionBlinded infusionHigh basal levelsAcute increaseAtherosclerotic lesionsPlatelet activationCocaine levelsMean percentPlatelet agonistsBasal levels
1986
FUNCTIONAL ASSESSMENT OF T CELL DEPLETION FROM BONE MARROW PRIOR TO THERAPEUTIC TRANSPLANTATION USING LIMITING DILUTION CULTURE METHODS
Rozans M, Smith B, Emerson S, Crimmins M, Laurent G, Reichert T, Burakoff S, Miller R. FUNCTIONAL ASSESSMENT OF T CELL DEPLETION FROM BONE MARROW PRIOR TO THERAPEUTIC TRANSPLANTATION USING LIMITING DILUTION CULTURE METHODS. Transplantation 1986, 42: 380-386. PMID: 3094209, DOI: 10.1097/00007890-198610000-00010.Peer-Reviewed Original ResearchConceptsT-cell depletionT cellsComplement-mediated depletionCell depletionFACS analysisIL-2Functional impairmentT-lymphocyte depletionT-cell contaminationBone marrow inoculumT cell setsComplement-mediated lysisDilution methodFlow cytometric methodLymphocyte depletionComplement treatmentMarrow inoculumCytotoxic effectorsInterleukin-2Functional assessmentT101 immunotoxinCulture methodCytometric methodCell contaminationEventual death
1984
Circulating Monoclonal B Lymphocytes in Non-Hodgkin's Lymphoma
Smith B, Weinberg D, Robert N, Towle M, Luther E, Pinkus G, Ault K. Circulating Monoclonal B Lymphocytes in Non-Hodgkin's Lymphoma. New England Journal Of Medicine 1984, 311: 1476-1481. PMID: 6438505, DOI: 10.1056/nejm198412063112304.Peer-Reviewed Original ResearchConceptsMonoclonal B lymphocytesMonoclonal lymphocytesLight chain typeB lymphocytesHodgkin's lymphomaSensitive flow cytometric methodBone marrow involvementDiffuse histiocytic lymphomaProlonged clinical remissionNon-Hodgkin lymphomaForms of lymphomaCategory of lymphomaClinical remissionComplete remissionFlow cytometric methodClinical stagingProlonged remissionsHistologic subclassificationPrognostic importanceHistiocytic lymphomaRemissionPatient's diseasePatientsLymphomaClonal excess