1996
The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation.
Leitenberg D, Novak TJ, Farber D, Smith BR, Bottomly K. The extracellular domain of CD45 controls association with the CD4-T cell receptor complex and the response to antigen-specific stimulation. Journal Of Experimental Medicine 1996, 183: 249-259. PMID: 8551228, PMCID: PMC2192406, DOI: 10.1084/jem.183.1.249.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAntigen PresentationBase SequenceCD4 AntigensCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineFlow CytometryImmunologic CappingLeukocyte Common AntigensLymphocyte ActivationMolecular Sequence DataPhenotypePhosphatidylinositol Diacylglycerol-LyasePhosphoric Diester HydrolasesProtein BindingReceptors, Antigen, T-CellRecombinant ProteinsStructure-Activity RelationshipTransfectionConceptsT cell receptorMolecular weight isoformsCD45 isoformsHigh molecular weight isoformsWeight isoformsAntigen-presenting cellsAntigen-specific stimulationT lymphocyte activationPanel of transfectantsLow molecular weight isoformsHigh molecular weight CD45 isoformsT helper 2 clonesCell receptor complexSpecific antigenT cell transfectants
1987
CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction.
Mentzer SJ, Smith BR, Barbosa JA, Crimmins MA, Herrmann SH, Burakoff SJ. CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction. The Journal Of Immunology 1987, 138: 1325-30. PMID: 3543126, DOI: 10.4049/jimmunol.138.5.1325.Peer-Reviewed Original ResearchConceptsHLA-A2CTL clonesHLA-B7Target cellsAntigen recognitionHuman CTL clonesTarget cell lysisCalcium-sensitive dye indo-1Cytolytic T lymphocytesCTL-target interactionDye indo-1CTL-target cell interactionAntigen-specific receptorsT cell receptorCell surface moleculesCTL activationT lymphocytesHuman CTLIndo-1LFA-1Free calciumCell receptorFlow cytometrySurface moleculesCell interactions