Featured Publications
Decreased Overall Survival in HIV-associated Non–small-cell Lung Cancer
Hysell K, Yusuf R, Barakat L, Virata M, Gan G, Deng Y, Perez-Irizarry J, Vega T, Goldberg SB, Emu B. Decreased Overall Survival in HIV-associated Non–small-cell Lung Cancer. Clinical Lung Cancer 2020, 22: e498-e505. PMID: 33468393, PMCID: PMC8169710, DOI: 10.1016/j.cllc.2020.11.006.Peer-Reviewed Original ResearchConceptsCell lung cancerGeneral patientsNSCLC populationLung cancerCox proportional hazards modelYale-New Haven HospitalGeneral NSCLC populationOutcomes of patientsOverall median survivalRetrospective cohort studyPredictors of survivalKaplan-Meier curvesHIV-1 RNACopies/mLLog-rank testProportional hazards modelNew Haven HospitalCancer treatment regimensMedian CD4Antiretroviral therapyCohort studyMedian survivalOverall survivalHIV infectionMedian age
2023
Impact of Head and Neck Cancer Treatment on CD4 T Cell Decline and Recovery in People with HIV
Hicks D, Salahuddin S, Wu M, Perez-Irizarry J, Emu B, Park H. Impact of Head and Neck Cancer Treatment on CD4 T Cell Decline and Recovery in People with HIV. International Journal Of Radiation Oncology • Biology • Physics 2023, 117: e588. DOI: 10.1016/j.ijrobp.2023.06.1934.Peer-Reviewed Original ResearchCells/mm3CD4 countPercentage of baselineMann-Whitney testCD4 T-cell declineMedian baseline CD4 countMedian nadir CD4 countCancer treatmentBaseline CD4 countCancer treatment initiationMedian baseline CD4Treatment-related immunosuppressionNadir CD4 countMajority of patientsRetrospective chart reviewTime of diagnosisStart of treatmentT-cell declineNeck cancer treatmentMATERIAL/METHODSNonparametric Mann-Whitney testBaseline CD4Immunologic declineMedian CD4Antiretroviral therapy