Factors associated with life expectancy (LE) < 3 months (mo) among older adults receiving palliative chemotherapy (chemo).
Hurria A, Hardt M, Tew W, Mohile S, Owusu C, Gross C, Gajra A, Lichtman S, Katheria V, Ramani R, Zavala L, Klepin H. Factors associated with life expectancy (LE) < 3 months (mo) among older adults receiving palliative chemotherapy (chemo). Journal Of Clinical Oncology 2012, 30: 9034-9034. DOI: 10.1200/jco.2012.30.15_suppl.9034.Peer-Reviewed Original ResearchUnintentional weight lossPoor physical functionMultivariate logistic regressionAdvanced cancerLife expectancyPhysical functionWeight lossBivariate analysisLogistic regressionOlder adultsGeriatric assessment variablesMulti-site cohort studyLimited life expectancyPhysical function measuresFunctional status measuresOlder ptsPalliative chemoPalliative chemotherapyPalliative intentCohort studyPatient ageLow albuminFunctional statusOptimal treatmentRisk factorsPredictors of early discontinuation of chemotherapy (EDC) in patients (pts) age 65 or older with stage IV non-small cell lung cancer (NSCLC).
Gajra A, Tew W, Hardt M, Mohile S, Owusu C, Klepin H, Gross C, Lichtman S, Katheria V, Hurria A. Predictors of early discontinuation of chemotherapy (EDC) in patients (pts) age 65 or older with stage IV non-small cell lung cancer (NSCLC). Journal Of Clinical Oncology 2012, 30: e18133-e18133. DOI: 10.1200/jco.2012.30.15_suppl.e18133.Peer-Reviewed Original ResearchStage IV non-small cell lung cancerNon-small cell lung cancerPoor physical functionOlder ptsPhysical functionAge 65Multi-site prospective studyBivariate analysisGeriatric assessment variablesPatients age 65Cell lung cancerMultivariate logistic regressionLower mean HbPt ageChemotherapy toxicityEarly discontinuationAlbumin levelsMean HbProspective studyPoor outcomeHigher cancerLung cancerPhysical scoresSubset analysisDisease progression