Addressing Recruitment Challenges in the Engage-HU Trial in Young Children with Sickle Cell Disease
Hood A, Strong H, Nwankwo C, Johnson Y, Mara C, Shook L, Brinkman W, Real F, Klein M, King A, Calhoun C, Smith-Whitley K, Creary S, Britto M, Saving K, Piccone C, Raphael J, Volanakis E, Hildenbrand A, Reader S, Rana S, Neumayr L, Yates A, Badawy S, Thompson A, Sobota A, Meier E, Quinn C, Crosby L. Addressing Recruitment Challenges in the Engage-HU Trial in Young Children with Sickle Cell Disease. Blood 2020, 136: 26-27. DOI: 10.1182/blood-2020-141471.Peer-Reviewed Original ResearchSickle cell diseaseSite principal investigatorsNational HeartCell diseaseCaregivers' perceptionsBluebird BioAdvisory CommitteeYoung childrenPrincipal investigatorBlood Institute guidelinesPatient-centered outcomesChild health outcomesRandomized control trialStepped-wedge designMonths of ageCurrent equity holderMistrust of researchStudy's principal investigatorNeurologic morbidityPrimary endpointTreat principleBlood InstituteFuture trialsIntervention trialsSCD population