2023
Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease
Harris K, Preiss L, Varughese T, Bauer A, Calhoun C, Treadwell M, Masese R, Hankins J, Hussain F, Glassberg J, Melvin C, Gibson R, King A. Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease. JAMA Network Open 2023, 6: e2314070. PMID: 37200033, PMCID: PMC10196879, DOI: 10.1001/jamanetworkopen.2023.14070.Peer-Reviewed Original ResearchConceptsSickle cell diseasePain frequencyMedical record abstractionPain severityMental healthHydroxyurea usePain medicationRecord abstractionCell diseaseMAIN OUTCOMEAdult Sickle Cell QualityElectronic medical record abstractionSickle Cell Disease Implementation ConsortiumDaily pain medicationHigher pain frequencySeverity of painRegular blood transfusionsMental health diagnosesPatient registry dataCross-sectional analysisAssociation of educationEmployment statusPain episodesPain reductionPain scores
2020
Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Protocol for an Efficacy and Implementation Study
Hankins JS, Shah N, DiMartino L, Brambilla D, Fernandez ME, Gibson RW, Gordeuk VR, Lottenberg R, Kutlar A, Melvin C, Simon J, Wun T, Treadwell M, Calhoun C, Baumann A, Potter MB, Klesges L, Bosworth H, . Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Protocol for an Efficacy and Implementation Study. JMIR Research Protocols 2020, 9: e16319. PMID: 32442144, PMCID: PMC7388044, DOI: 10.2196/16319.Peer-Reviewed Original ResearchSickle Cell Disease Implementation ConsortiumSickle cell diseaseINTERNATIONAL REGISTERED REPORT IDENTIFIERMHealth interventionsDisease complicationsSickle cell disease careAcute disease complicationsImplementation-effectiveness studyNational Health LungHealth-related qualityEvidence-based guidelinesProportion of daysHealth appsHealth LungHydroxyurea useHydroxyurea therapyAppropriate prescribingMedication adherenceDisease careChronic diseasesMobile health appsCell diseasePrescribing behaviorHealth literacyPatients
2016
Higher Prevalence of Hydroxyurea Use Is Associated with Lower Hospitalization Rate in a Population of Children with Sickle Cell Disease
Calhoun C, Colvin R, Verlekar A, Lassa-Claxton S, Cole F, Hulbert M. Higher Prevalence of Hydroxyurea Use Is Associated with Lower Hospitalization Rate in a Population of Children with Sickle Cell Disease. Blood 2016, 128: 315. DOI: 10.1182/blood.v128.22.315.315.Peer-Reviewed Original ResearchSt. Louis Children's HospitalSickle cell diseaseLower hospitalization ratesHematopoietic stem cell transplantPopulation of childrenStem cell transplantHospitalization ratesSevere genotypeCell diseaseGenotype groupsHydroxyurea useTotal hospitalizationsCell transplantOutpatient encountersVaso-occlusive pain episodesHU treatmentStudy periodImpact of hydroxyureaMore outpatient encountersReduced hospitalization ratesHigher hospitalization ratesRate of hospitalizationICD-9 codesUnrelated medical conditionsGenotypes of SCD