1994
Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial.
Ment L, Ehrenkranz R, Duncan C, Scott D, Taylor K, Katz K, Schneider K, Makuch R, Oh W, Vohr B, Philip A, Allan W. Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics 1994, 93: 543-50. PMID: 8134206, DOI: 10.1542/peds.93.4.543.Peer-Reviewed Original ResearchConceptsLow birth weight neonatesSeverity of IVHBirth weight neonatesIntraventricular hemorrhageWeight neonatesDose indomethacinBirth weightGrade 4 intraventricular hemorrhageSerial cranial ultrasound examinationsSignificant adverse drug eventsPercent of neonatesPlacebo-controlled trialPatent ductus arteriosusCranial ultrasound examinationMajor risk factorAdverse drug eventsHours of ageFirst postnatal dayDuctal closureProphylactic indomethacinApgar scoreNeurodevelopmental handicapParenchymal involvementPlacebo groupAdverse events
1984
Delayed Hemorrhagic Infarction: A Cause of Late Neonatal Germinal Matrix and Intraventricular Hemorrhage
Ment L, Ehrenkranz R, Duncan C, Lange R. Delayed Hemorrhagic Infarction: A Cause of Late Neonatal Germinal Matrix and Intraventricular Hemorrhage. JAMA Neurology 1984, 41: 1036-1039. PMID: 6477210, DOI: 10.1001/archneur.1984.04050210034010.Peer-Reviewed Original ResearchConceptsCerebral blood flowLow cerebral blood flowLate intraventricular hemorrhageIntraventricular hemorrhageFirst postnatal dayMonths of ageSeries of insultsProfound hypotensionPorencephalic cystPostnatal eventsGerminal matrixPostnatal dayBlood flowHemorrhageNeonatesTomographic evidenceInfarcted tissueHypotensionTissueAsphyxiaEncephalomalaciaInfarctionInfantsCystsInsult