1988
Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates
Ment L, Duncan C, Ehrenkranz R, Kleinman C, Taylor K, Scott D, Gettner P, Sherwonit E, Williams J. Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates. The Journal Of Pediatrics 1988, 112: 948-955. PMID: 3373405, DOI: 10.1016/s0022-3476(88)80225-7.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageGerminal matrixPostnatal hoursUrinary outputDay 5Placebo-controlled prospective trialLow birth weight neonatesDuctus arteriosus shuntIndomethacin-treated infantsSerum indomethacin levelsBirth weight neonatesCardiac ultrasound studiesAdequate urinary outputGroups of infantsIndomethacin trialStudy medicationApgar scorePreterm neonatesProspective trialWeight neonatesDuctus arteriosusGestational ageSerum electrolytesBirth weightPatent ductus
1986
Beagle puppy model of perinatal cerebral insults. Cerebral blood flow changes and intraventricular hemorrhage evoked by hypoxemia.
Ment L, Stewart W, Duncan C, Pitt B. Beagle puppy model of perinatal cerebral insults. Cerebral blood flow changes and intraventricular hemorrhage evoked by hypoxemia. Journal Of Neurosurgery 1986, 65: 847-50. PMID: 3772483, DOI: 10.3171/jns.1986.65.6.0847.Peer-Reviewed Original ResearchConceptsCerebral blood flowWhite matterIntraventricular hemorrhageRegional cerebral blood flowCerebral blood flow changesNeonatal cerebral infarctionPerinatal cerebral insultsParieto-occipital white matterEffects of hypoxemiaBeagle puppy modelNewborn beagle pupsBlood flow changesTemporal white matterParietal white matterCentral gray regionNeuropathological injuryCerebral infarctionPerinatal asphyxiaCerebral insultNeuropathological changesPuppy modelCommon causeGerminal matrixBeagle pupsBlood flow
1985
Early Childhood Developmental Follow-Up of Infants with GMH/IVH: Effect of Methylxanthine Therapy
Ment L, Scott D, Ehrenkranz R, Duncan C. Early Childhood Developmental Follow-Up of Infants with GMH/IVH: Effect of Methylxanthine Therapy. American Journal Of Perinatology 1985, 2: 223-227. PMID: 4015773, DOI: 10.1055/s-2007-999955.Peer-Reviewed Original ResearchConceptsGMH/IVHMethylxanthine therapyCerebral blood flowBlood flowSmall preterm neonatesBayley mental scoresIdiopathic apneaBirthweight neonatesPreterm neonatesIntraventricular hemorrhageNeurodevelopmental outcomesNeonatal periodMental scoresGerminal matrixTherapyIVHUnderlying disturbanceInfantsAdverse effectsFurther studiesNeonatesCognitive functioningHarmful effectsMetabolismApneaNeurodevelopmental assessment of very low birth weight neonates: Effect of germinal matrix and intraventricular hemorrhage
Ment L, Scott D, Ehrenkranz R, Duncan C. Neurodevelopmental assessment of very low birth weight neonates: Effect of germinal matrix and intraventricular hemorrhage. Pediatric Neurology 1985, 1: 164-168. PMID: 3880401, DOI: 10.1016/0887-8994(85)90058-x.Peer-Reviewed Original ResearchConceptsGMH/IVHIntraventricular hemorrhageNeurodevelopmental assessmentGerminal matrixSurviving infantsNeonatal germinal matrix hemorrhageNewborn Special Care UnitLow birth weight neonatesBirth weight neonatesGerminal matrix hemorrhageMajor neurologic abnormalitiesSpecial care unitsNon-hemorrhage groupWeight neonatesCare unitGroup infantsPostnatal hoursNeurologic abnormalitiesBirth weightSevere gradesHemorrhageDevelopmental scoresBayley ScalesInfantsInfant development
1984
Delayed Hemorrhagic Infarction: A Cause of Late Neonatal Germinal Matrix and Intraventricular Hemorrhage
Ment L, Ehrenkranz R, Duncan C, Lange R. Delayed Hemorrhagic Infarction: A Cause of Late Neonatal Germinal Matrix and Intraventricular Hemorrhage. JAMA Neurology 1984, 41: 1036-1039. PMID: 6477210, DOI: 10.1001/archneur.1984.04050210034010.Peer-Reviewed Original ResearchConceptsCerebral blood flowLow cerebral blood flowLate intraventricular hemorrhageIntraventricular hemorrhageFirst postnatal dayMonths of ageSeries of insultsProfound hypotensionPorencephalic cystPostnatal eventsGerminal matrixPostnatal dayBlood flowHemorrhageNeonatesTomographic evidenceInfarcted tissueHypotensionTissueAsphyxiaEncephalomalaciaInfarctionInfantsCystsInsultBeagle puppy model of intraventricular hemorrhage. Effect of indomethacin on local cerebral glucose utilization.
Ment L, Stewart W, Duncan C, Scott D, Lambrecht R. Beagle puppy model of intraventricular hemorrhage. Effect of indomethacin on local cerebral glucose utilization. Journal Of Neurosurgery 1984, 60: 737-42. PMID: 6707743, DOI: 10.3171/jns.1984.60.4.0737.Peer-Reviewed Original ResearchConceptsLocal cerebral glucose utilizationCerebral glucose utilizationIntraventricular hemorrhageSaline-pretreated animalsNewborn beagle puppiesBeagle puppiesGlucose utilizationIncidence of IVHBlood pressure responseNeonatal intraventricular hemorrhageEffect of indomethacinBeagle puppy modelCerebral metabolismPuppy modelGerminal matrixWhite matterIndomethacinMarked alterationsInsultSignificant alterationsPressure responseHemorrhagePupsPuppiesAlterationsPosthemorrhagic hydrocephalus. Low incidence in very low birth weight neonates with intraventricular hemorrhage.
Ment L, Duncan C, Scott D, Ehrenkranz R. Posthemorrhagic hydrocephalus. Low incidence in very low birth weight neonates with intraventricular hemorrhage. Journal Of Neurosurgery 1984, 60: 343-7. PMID: 6693962, DOI: 10.3171/jns.1984.60.2.0343.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhagePosthemorrhagic hydrocephalusLong-term neurodevelopmental handicapsNewborn Special Care UnitLow birth weight neonatesCranial ultrasound scanningCranial ultrasound studiesBirth weight neonatesBirth weight rangeCongenital aqueductal stenosisElevated intracranial pressureSpecial care unitsOccipitofrontal head circumferenceNon-hemorrhage groupNeurodevelopmental handicapPreterm infantsWeight neonatesCare unitPostnatal hoursAqueductal stenosisBirth weightEqual incidenceIntracranial pressureHead circumferenceGerminal matrix